Iron in PDB 4kbz: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-Hydroxy-Pyridin-2-Yl)-Thiazol-4-Yl]- Acetylamino}-Phenyl-Acetic Acid

Enzymatic activity of Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-Hydroxy-Pyridin-2-Yl)-Thiazol-4-Yl]- Acetylamino}-Phenyl-Acetic Acid

Protein crystallography data

Iron Binding Sites:

Iron binding site 1 out of 1 in 4kbz

Iron Binding Sites List in 4kbz

Iron binding site 1 out of 1 in the Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-Hydroxy-Pyridin-2-Yl)-Thiazol-4-Yl]- Acetylamino}-Phenyl-Acetic Acid


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-Hydroxy-Pyridin-2-Yl)-Thiazol-4-Yl]- Acetylamino}-Phenyl-Acetic Acid within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe502 b:35.7 occ:1.00 NE2 A:HIS374 2.1 31.2 1.0 N8 A:1QA501 2.1 63.9 1.0 O A:HOH624 2.2 25.8 1.0 OD1 A:ASP315 2.2 30.5 1.0 NE2 A:HIS313 2.2 43.2 1.0 N4 A:1QA501 2.3 61.0 1.0 C7 A:1QA501 2.8 65.0 1.0 C5 A:1QA501 2.9 64.4 1.0 CE1 A:HIS374 2.9 30.7 1.0 CE1 A:HIS313 3.1 43.7 1.0 CD2 A:HIS374 3.2 33.7 1.0 CG A:ASP315 3.2 32.2 1.0 CD2 A:HIS313 3.2 43.9 1.0 C9 A:1QA501 3.4 64.2 1.0 C3 A:1QA501 3.4 61.1 1.0 OD2 A:ASP315 3.4 34.9 1.0 C12 A:1QA501 3.9 64.0 1.0 ND1 A:HIS374 4.1 31.4 1.0 CG A:HIS374 4.2 34.7 1.0 ND1 A:HIS313 4.3 43.3 1.0 CG A:HIS313 4.3 43.3 1.0 C6 A:1QA501 4.3 64.4 1.0 S11 A:1QA501 4.4 65.7 1.0 C10 A:1QA501 4.4 65.1 1.0 CB A:ASP315 4.6 32.8 1.0 C2 A:1QA501 4.7 61.2 1.0 CA A:ASP315 4.9 35.2 1.0 CZ A:PHE366 4.9 31.6 1.0 N A:ASP315 4.9 35.4 1.0

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