Iron in PDB 4nm6: Crystal Structure of TET2-Dna Complex

The structure of Crystal Structure of TET2-Dna Complex, PDB code: 4nm6 was solved by L.Hu, Z.Li, J.Cheng, Q.Rao, W.Gong, M.Liu, P.Wang, Y.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.80 / 2.03
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	48.296, 88.186, 262.962, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 24.3

The structure of Crystal Structure of TET2-Dna Complex also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Iron atom in the Crystal Structure of TET2-Dna Complex (pdb code 4nm6). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of TET2-Dna Complex, PDB code: 4nm6:

Iron binding site 1 out of 1 in the Crystal Structure of TET2-Dna Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of TET2-Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe2004 b:43.9 occ:1.00 NE2 A:HIS1881 2.2 41.1 1.0 NE2 A:HIS1382 2.3 37.7 1.0 O1 A:OGA2005 2.4 65.9 1.0 O A:HOH2149 2.4 50.7 1.0 O2' A:OGA2005 2.4 51.5 1.0 OD1 A:ASP1384 2.5 49.7 1.0 CE1 A:HIS1382 3.0 36.8 1.0 C2 A:OGA2005 3.1 58.9 1.0 OD2 A:ASP1384 3.1 55.5 1.0 C1 A:OGA2005 3.1 63.8 1.0 CG A:ASP1384 3.1 50.9 1.0 CE1 A:HIS1881 3.1 38.7 1.0 CD2 A:HIS1881 3.2 44.9 1.0 CD2 A:HIS1382 3.4 44.2 1.0 ND1 A:HIS1382 4.1 47.0 1.0 ND1 A:HIS1881 4.3 39.7 1.0 CG A:HIS1881 4.3 43.5 1.0 O2 A:OGA2005 4.3 66.2 1.0 N1 A:OGA2005 4.3 57.8 1.0 CG A:HIS1382 4.4 42.4 1.0 NH2 A:ARG1261 4.5 53.5 1.0 CB A:ASP1384 4.6 40.1 1.0 CB A:ALA1876 4.6 34.7 1.0 N A:ASP1384 4.9 40.7 1.0 C5A B:5CM6 5.0 68.8 1.0

L.Hu, Z.Li, J.Cheng, Q.Rao, W.Gong, M.Liu, Y.G.Shi, J.Zhu, P.Wang, Y.Xu. Crystal Structure of TET2-Dna Complex: Insight Into Tet-Mediated 5MC Oxidation. Cell(Cambridge,Mass.) V. 155 1545 2013.
ISSN: ISSN 0092-8674
PubMed: 24315485
DOI: 10.1016/J.CELL.2013.11.020