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Iron in PDB 4nz2: Crystal Structure of CYP2C9 in Complex with An InhibitorEnzymatic activity of Crystal Structure of CYP2C9 in Complex with An Inhibitor
All present enzymatic activity of Crystal Structure of CYP2C9 in Complex with An Inhibitor:
1.14.13.48; 1.14.13.49; 1.14.13.80; Protein crystallography data
The structure of Crystal Structure of CYP2C9 in Complex with An Inhibitor, PDB code: 4nz2
was solved by
G.Branden,
T.Sjogren,
Y.Xue,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4nz2:
The structure of Crystal Structure of CYP2C9 in Complex with An Inhibitor also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of CYP2C9 in Complex with An Inhibitor
(pdb code 4nz2). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of CYP2C9 in Complex with An Inhibitor, PDB code: 4nz2: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 4nz2Go back to Iron Binding Sites List in 4nz2
Iron binding site 1 out
of 2 in the Crystal Structure of CYP2C9 in Complex with An Inhibitor
Mono view Stereo pair view
Iron binding site 2 out of 2 in 4nz2Go back to Iron Binding Sites List in 4nz2
Iron binding site 2 out
of 2 in the Crystal Structure of CYP2C9 in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
G.Branden,
T.Sjogren,
V.Schnecke,
Y.Xue.
Structure-Based Ligand Design to Overcome Cyp Inhibition in Drug Discovery Projects. Drug Discov Today V. 19 905 2014.
Page generated: Sun Dec 13 15:43:23 2020
ISSN: ISSN 1359-6446 PubMed: 24642031 DOI: 10.1016/J.DRUDIS.2014.03.012 |
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