Atomistry » Iron » PDB 4ud6-4uh0 » 4ugc
Atomistry »
  Iron »
    PDB 4ud6-4uh0 »
      4ugc »

Iron in PDB 4ugc: Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine)

Enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine)

All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine):
1.14.13.165;

Protein crystallography data

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine), PDB code: 4ugc was solved by J.K.Holden, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.83 / 1.80
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.663, 94.783, 62.813, 90.00, 90.00, 90.00
R / Rfree (%) 16 / 18.7

Other elements in 4ugc:

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine) also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine) (pdb code 4ugc). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine), PDB code: 4ugc:

Iron binding site 1 out of 1 in 4ugc

Go back to Iron Binding Sites List in 4ugc
Iron binding site 1 out of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Bacillus Subtilis Nitric Oxide Synthase in Complex with 6,6'-(((2S)-3-Aminopropane-1,2-Diyl)Bis(Oxymethanediyl))Bis(4- Methylpyridin-2-Amine) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe901

b:12.2
occ:1.00
 FE A:HEM901 0.0 12.2 1.0
ND A:HEM901 1.9 13.2 1.0
NA A:HEM901 2.0 10.8 1.0
NC A:HEM901 2.1 8.2 1.0
NB A:HEM901 2.1 11.2 1.0
SG A:CYS66 2.5 11.7 1.0
C1D A:HEM901 2.9 13.4 1.0
C4D A:HEM901 3.0 15.2 1.0
C1A A:HEM901 3.0 15.0 1.0
C4C A:HEM901 3.1 10.8 1.0
C4B A:HEM901 3.1 9.3 1.0
C4A A:HEM901 3.1 9.9 1.0
C1B A:HEM901 3.1 9.9 1.0
C1C A:HEM901 3.1 10.6 1.0
CB A:CYS66 3.4 9.4 1.0
CHD A:HEM901 3.4 14.1 1.0
CHA A:HEM901 3.5 17.2 1.0
CHB A:HEM901 3.5 10.1 1.0
CHC A:HEM901 3.5 10.0 1.0
C04 A:1Q6904 3.9 18.1 1.0
C03 A:1Q6904 4.0 16.8 1.0
CA A:CYS66 4.2 10.6 1.0
C2D A:HEM901 4.2 15.7 1.0
C3D A:HEM901 4.2 12.1 1.0
C05 A:1Q6904 4.2 28.6 1.0
C3A A:HEM901 4.3 12.4 1.0
C07 A:1Q6904 4.3 17.8 1.0
C2A A:HEM901 4.3 14.0 1.0
C3C A:HEM901 4.3 11.5 1.0
C2C A:HEM901 4.3 11.3 1.0
C2B A:HEM901 4.3 9.2 1.0
C02 A:1Q6904 4.3 17.8 1.0
C3B A:HEM901 4.3 10.9 1.0
NE1 A:TRP60 4.5 11.0 1.0
C06 A:1Q6904 4.6 31.9 1.0
N01 A:1Q6904 4.6 24.7 1.0
N A:GLY68 4.9 10.9 1.0
C A:CYS66 4.9 13.1 1.0
N02 A:1Q6904 5.0 13.4 1.0

Reference:

J.K.Holden, D.Dejam, M.C.Lewis, H.Huang, S.Kang, Q.Jing, F.Xue, R.B.Silverman, T.L.Poulos. Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase. Biochemistry V. 54 4075 2015.
ISSN: ISSN 0006-2960
PubMed: 26062720
DOI: 10.1021/ACS.BIOCHEM.5B00431
Page generated: Mon Aug 5 12:40:20 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy