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Atomistry » Iron » PDB 5foi-5g6d » 5g5j | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 5foi-5g6d » 5g5j » |
Iron in PDB 5g5j: Crystal Structure of Human CYP3A4 Bound to MetforminEnzymatic activity of Crystal Structure of Human CYP3A4 Bound to Metformin
All present enzymatic activity of Crystal Structure of Human CYP3A4 Bound to Metformin:
1.14.13.157; 1.14.13.32; 1.14.13.67; 1.14.14.1; Protein crystallography data
The structure of Crystal Structure of Human CYP3A4 Bound to Metformin, PDB code: 5g5j
was solved by
I.Sevrioukova,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Human CYP3A4 Bound to Metformin
(pdb code 5g5j). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Human CYP3A4 Bound to Metformin, PDB code: 5g5j: Iron binding site 1 out of 1 in 5g5jGo back to Iron Binding Sites List in 5g5j
Iron binding site 1 out
of 1 in the Crystal Structure of Human CYP3A4 Bound to Metformin
Mono view Stereo pair view
Reference:
Z.Guo,
I.F.Sevrioukova,
I.G.Denisov,
X.Zhang,
T.L.Chiu,
D.G.Thomas,
E.A.Hanse,
R.A.D.Cuellar,
Y.V.Grinkova,
V.W.Langenfeld,
D.S.Swedien,
J.D.Stamschror,
J.Alvarez,
F.Luna,
A.Galvan,
Y.K.Bae,
J.D.Wulfkuhle,
R.I.Gallagher,
E.F.Petricoin,
B.Norris,
C.M.Flory,
R.J.Schumacher,
M.G.O'sullivan,
Q.Cao,
H.Chu,
J.D.Lipscomb,
W.M.Atkins,
K.Gupta,
A.Kelekar,
I.A.Blair,
J.H.Capdevila,
J.R.Falck,
S.G.Sligar,
T.L.Poulos,
G.I.Georg,
E.Ambrose,
D.A.Potter.
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chem Biol V. 24 1259 2017.
Page generated: Sun Dec 13 16:02:00 2020
ISSN: ESSN 2451-9456 PubMed: 28919040 DOI: 10.1016/J.CHEMBIOL.2017.08.009 |
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