Atomistry » Iron » PDB 5g65-5gxg » 5g6c
Atomistry »
  Iron »
    PDB 5g65-5gxg »
      5g6c »

Iron in PDB 5g6c: Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine

Enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine

All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine:
1.14.13.165;

Protein crystallography data

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine, PDB code: 5g6c was solved by J.K.Holden, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.09 / 2.13
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.860, 94.670, 61.780, 90.00, 90.00, 90.00
R / Rfree (%) 20.4 / 25.2

Other elements in 5g6c:

The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine also contains other interesting chemical elements:

Fluorine (F) 1 atom
Chlorine (Cl) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine (pdb code 5g6c). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine, PDB code: 5g6c:

Iron binding site 1 out of 1 in 5g6c

Go back to Iron Binding Sites List in 5g6c
Iron binding site 1 out of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with 7-((3-Fluorophenethylamino)Ethyl)Quinolin-2-Amine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe901

b:31.9
occ:1.00
 FE A:HEM901 0.0 31.9 1.0
ND A:HEM901 1.9 29.0 1.0
NA A:HEM901 2.0 31.4 1.0
NC A:HEM901 2.1 30.5 1.0
NB A:HEM901 2.1 28.7 1.0
SG A:CYS66 2.6 33.8 1.0
C1D A:HEM901 2.9 29.8 1.0
C4D A:HEM901 2.9 29.3 1.0
C1A A:HEM901 3.0 31.2 1.0
C4C A:HEM901 3.0 30.8 1.0
C4A A:HEM901 3.1 31.2 1.0
C4B A:HEM901 3.1 29.5 1.0
C1B A:HEM901 3.1 30.1 1.0
C1C A:HEM901 3.1 29.6 1.0
C04 A:M48904 3.3 33.2 1.0
CHD A:HEM901 3.3 30.9 1.0
CHA A:HEM901 3.4 30.9 1.0
CB A:CYS66 3.4 31.2 1.0
CHC A:HEM901 3.5 29.3 1.0
CHB A:HEM901 3.5 30.4 1.0
C05 A:M48904 3.6 34.6 1.0
C03 A:M48904 3.7 32.5 1.0
C06 A:M48904 4.0 35.6 1.0
C2D A:HEM901 4.1 30.1 1.0
C3D A:HEM901 4.2 30.0 1.0
CA A:CYS66 4.2 30.3 1.0
C2A A:HEM901 4.2 31.9 1.0
C3A A:HEM901 4.2 32.2 1.0
C3C A:HEM901 4.3 31.0 1.0
C2C A:HEM901 4.3 30.1 1.0
C10 A:M48904 4.3 34.5 1.0
C2B A:HEM901 4.3 29.2 1.0
C3B A:HEM901 4.4 29.9 1.0
C02 A:M48904 4.4 32.0 1.0
NE1 A:TRP60 4.6 35.2 1.0
N01 A:M48904 4.6 32.8 1.0
C07 A:M48904 4.9 36.8 1.0
C A:CYS66 5.0 30.9 1.0
N A:GLY68 5.0 33.4 1.0

Reference:

J.K.Holden, M.C.Lewis, M.A.Cinelli, Z.Abdullatif, A.V.Pensa, R.B.Silverman, T.L.Poulos. Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry V. 55 5587 2016.
ISSN: ISSN 1520-4995
PubMed: 27607918
DOI: 10.1021/ACS.BIOCHEM.6B00786
Page generated: Sun Dec 13 16:02:09 2020

Last articles

Tb in 6TVY
Si in 6Y7O
Rh in 6WRM
Rh in 6WRL
Ni in 6Y8Z
Ni in 6Y8Y
Na in 6ZXZ
Na in 7ACG
Na in 6YLS
Na in 6Y8Z
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy