Iron in PDB 5jk5: Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex

All present enzymatic activity of Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex:
1.14.16.1; 1.14.16.4;

The structure of Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex, PDB code: 5jk5 was solved by N.Zhuang, K.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.45 / 2.07
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	70.968, 85.326, 74.894, 90.00, 110.23, 90.00
R / Rfree (%)	16.5 / 22.8

The binding sites of Iron atom in the Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex (pdb code 5jk5). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex, PDB code: 5jk5:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:28.1 occ:1.00 O A:HOH723 2.0 38.0 1.0 NE2 A:HIS278 2.0 22.3 1.0 OE2 A:GLU318 2.1 29.1 1.0 NE2 A:HIS273 2.1 31.8 1.0 O A:HOH607 2.3 52.8 1.0 O A:HOH703 2.4 30.6 1.0 CD A:GLU318 2.9 32.8 1.0 CD2 A:HIS278 3.0 25.3 1.0 OE1 A:GLU318 3.0 41.2 1.0 CD2 A:HIS273 3.0 27.6 1.0 CE1 A:HIS278 3.1 23.8 1.0 CE1 A:HIS273 3.1 25.8 1.0 O4 A:HBI503 3.8 33.6 1.0 CG A:HIS278 4.1 24.0 1.0 ND1 A:HIS278 4.1 24.3 1.0 O A:HOH764 4.2 49.5 1.0 ND1 A:HIS273 4.2 30.2 1.0 CG A:HIS273 4.2 34.0 1.0 CG A:GLU318 4.3 35.0 1.0 OE2 A:GLU274 4.5 29.4 1.0 CB A:ALA333 4.6 26.0 1.0 OH A:TYR313 4.8 30.8 1.0 CB A:PRO269 5.0 26.9 1.0 C4 A:HBI503 5.0 37.6 1.0

Iron binding site 2 out of 2 in the Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe501 b:28.2 occ:1.00 NE2 B:HIS278 2.0 18.7 1.0 O B:HOH720 2.0 33.6 1.0 NE2 B:HIS273 2.0 31.4 1.0 OE2 B:GLU318 2.3 26.0 1.0 O B:HOH700 2.3 28.2 1.0 O B:HOH618 2.4 46.5 1.0 CE1 B:HIS278 2.9 22.3 1.0 CD B:GLU318 3.0 33.5 1.0 CD2 B:HIS273 3.0 26.9 1.0 CD2 B:HIS278 3.0 20.5 1.0 CE1 B:HIS273 3.0 27.1 1.0 OE1 B:GLU318 3.0 37.8 1.0 O4 B:HBI503 3.8 33.9 1.0 ND1 B:HIS278 4.0 21.5 1.0 ND1 B:HIS273 4.1 33.1 1.0 CG B:HIS278 4.1 19.2 1.0 CG B:HIS273 4.2 33.0 1.0 CG B:GLU318 4.4 33.7 1.0 OE2 B:GLU274 4.5 26.4 1.0 CB B:ALA333 4.5 22.0 1.0 O B:HOH708 4.5 46.6 1.0 O B:HOH758 4.5 49.6 1.0 OH B:TYR313 4.7 31.5 1.0 CB B:PRO269 4.8 40.4 1.0 C4 B:HBI503 5.0 39.2 1.0

N.Zhuang, K.H.Lee. Phenylalanine Hydroxylase From Dictyostelium - BH2 Complex To Be Published.