Iron in PDB 5jk8: Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex

All present enzymatic activity of Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex:
1.14.16.1; 1.14.16.4;

The structure of Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex, PDB code: 5jk8 was solved by N.Zhuang, K.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.74 / 2.39
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	71.516, 85.668, 73.482, 90.00, 110.08, 90.00
R / Rfree (%)	16.5 / 24.2

The binding sites of Iron atom in the Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex (pdb code 5jk8). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex, PDB code: 5jk8:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe703 b:61.9 occ:1.00 NE2 A:HIS278 2.0 49.9 1.0 NE2 A:HIS273 2.0 71.4 1.0 O A:HOH802 2.2 60.4 1.0 OE2 A:GLU318 2.3 78.9 1.0 OE1 A:GLU318 2.4 63.3 1.0 CD A:GLU318 2.6 69.1 1.0 O A:HOH801 2.7 88.9 1.0 CE1 A:HIS278 2.8 57.1 1.0 CE1 A:HIS273 3.0 75.6 1.0 CD2 A:HIS273 3.0 69.1 1.0 CD2 A:HIS278 3.1 52.7 1.0 O4 A:HBI702 3.9 0.1 1.0 ND1 A:HIS278 4.0 46.4 1.0 CD A:NLE704 4.0 70.8 1.0 CG A:GLU318 4.1 72.9 1.0 ND1 A:HIS273 4.1 75.2 1.0 CG A:HIS278 4.1 44.6 1.0 CG A:HIS273 4.1 73.7 1.0 CB A:ALA333 4.5 66.6 1.0 CE A:NLE704 4.5 71.8 1.0 OH A:TYR313 4.5 73.6 1.0 OE2 A:GLU274 4.5 66.2 1.0

Iron binding site 2 out of 2 in the Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe503 b:56.4 occ:1.00 NE2 B:HIS278 2.0 59.4 1.0 O B:HOH622 2.0 83.9 1.0 NE2 B:HIS273 2.1 67.3 1.0 OE1 B:GLU318 2.3 73.7 1.0 OE2 B:GLU318 2.6 81.1 1.0 O B:HOH608 2.7 66.8 1.0 CD B:GLU318 2.8 74.0 1.0 CE1 B:HIS278 2.9 55.9 1.0 O B:HOH601 3.0 83.2 1.0 CD2 B:HIS278 3.0 62.0 1.0 CD2 B:HIS273 3.0 68.0 1.0 CE1 B:HIS273 3.1 67.2 1.0 O4 B:HBI502 3.7 0.1 1.0 ND1 B:HIS278 4.0 53.8 1.0 CG B:HIS278 4.1 52.0 1.0 CG B:HIS273 4.2 69.3 1.0 ND1 B:HIS273 4.2 67.0 1.0 CG B:GLU318 4.2 71.3 1.0 CE B:NLE504 4.4 72.1 1.0 CD B:NLE504 4.5 77.4 1.0 OE2 B:GLU274 4.5 60.9 1.0 CB B:ALA333 4.5 51.1 1.0 OH B:TYR313 4.8 63.4 1.0 CB B:PRO269 4.9 69.5 1.0 C4 B:HBI502 4.9 0.6 1.0 CZ B:PHE251 4.9 60.7 1.0

N.Zhuang, K.H.Lee. Phenylalanine Hydroxylase From Dictyostelium - BH2, Norleucine Complex To Be Published.