Atomistry » Iron » PDB 5j84-5jrx » 5jl7
Atomistry »
  Iron »
    PDB 5j84-5jrx »
      5jl7 »

Iron in PDB 5jl7: Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3

Enzymatic activity of Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3

All present enzymatic activity of Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3:
1.14.14.14;

Protein crystallography data

The structure of Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3, PDB code: 5jl7 was solved by D.Ghosh, J.Lo, C.Egbuta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.69 / 3.10
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 140.333, 140.333, 118.958, 90.00, 90.00, 120.00
R / Rfree (%) 18.5 / 20.7

Iron Binding Sites:

The binding sites of Iron atom in the Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3 (pdb code 5jl7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3, PDB code: 5jl7:

Iron binding site 1 out of 1 in 5jl7

Go back to Iron Binding Sites List in 5jl7
Iron binding site 1 out of 1 in the Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Placental Aromatase Cytochrome P450 (CYP19A1): Androstenedione Complex #3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe600

b:67.4
occ:1.00
FE A:HEM600 0.0 67.4 1.0
ND A:HEM600 1.9 67.2 1.0
NA A:HEM600 2.0 62.3 1.0
NB A:HEM600 2.1 63.8 1.0
NC A:HEM600 2.1 65.6 1.0
SG A:CYS437 2.4 69.3 1.0
C1D A:HEM600 2.9 65.9 1.0
C4D A:HEM600 2.9 65.3 1.0
C1A A:HEM600 3.0 63.1 1.0
C4A A:HEM600 3.0 62.0 1.0
C4B A:HEM600 3.0 67.9 1.0
C1B A:HEM600 3.0 66.3 1.0
C4C A:HEM600 3.1 66.1 1.0
C1C A:HEM600 3.1 67.8 1.0
CHA A:HEM600 3.4 63.1 1.0
CHD A:HEM600 3.4 66.1 1.0
CHB A:HEM600 3.4 63.3 1.0
CHC A:HEM600 3.4 67.6 1.0
CB A:CYS437 3.5 72.3 1.0
C19 A:ASD601 3.7 71.6 1.0
C2D A:HEM600 4.2 65.3 1.0
C3D A:HEM600 4.2 63.6 1.0
CA A:CYS437 4.2 71.7 1.0
C2A A:HEM600 4.2 65.8 1.0
C3A A:HEM600 4.2 64.8 1.0
C2B A:HEM600 4.3 68.0 1.0
C2C A:HEM600 4.3 70.6 1.0
C3B A:HEM600 4.3 70.0 1.0
C3C A:HEM600 4.3 69.8 1.0
C1 A:ASD601 4.6 73.0 1.0
N A:GLY439 4.7 73.9 1.0
C A:CYS437 4.8 71.2 1.0
C10 A:ASD601 4.8 72.5 1.0
N A:ALA438 4.9 72.1 1.0
C2 A:ASD601 4.9 72.5 1.0

Reference:

D.Ghosh, C.Egbuta, J.Lo. Testosterone Complex and Non-Steroidal Ligands of Human Aromatase. J. Steroid Biochem. Mol. 2018BIOL..
ISSN: ISSN 1879-1220
PubMed: 29476820
DOI: 10.1016/J.JSBMB.2018.02.009
Page generated: Sun Dec 13 16:04:24 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy