Iron in PDB 5jwk: Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate

All present enzymatic activity of Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate:
1.14.11.30;

The structure of Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate, PDB code: 5jwk was solved by C.Y.Taabazuing, S.C.Garman, M.J.Knapp, S.Eron, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.84 / 2.30
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	86.131, 86.131, 149.213, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 22.7

The binding sites of Iron atom in the Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate (pdb code 5jwk). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate, PDB code: 5jwk:

Iron binding site 1 out of 1 in the Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Factor Inhibiting Hif D201E in Complex with Fe, and Alpha- Ketoglutarate within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe403 b:45.2 occ:1.00 O2 A:AKG401 1.9 51.8 1.0 OE1 A:GLU201 1.9 33.8 1.0 O5 A:AKG401 2.1 42.8 1.0 O A:HOH509 2.2 56.0 1.0 NE2 A:HIS199 2.2 42.5 1.0 NE2 A:HIS279 2.3 42.4 1.0 C1 A:AKG401 2.6 45.4 1.0 C2 A:AKG401 2.7 45.5 1.0 CD A:GLU201 2.9 43.0 1.0 CD2 A:HIS279 3.1 43.3 1.0 CE1 A:HIS199 3.1 43.7 1.0 OE2 A:GLU201 3.2 43.0 1.0 CD2 A:HIS199 3.3 38.5 1.0 CE1 A:HIS279 3.3 42.1 1.0 O1 A:AKG401 3.8 45.8 1.0 O A:HOH567 4.1 39.5 1.0 C3 A:AKG401 4.1 41.8 1.0 CG A:GLU201 4.3 45.0 1.0 CZ2 A:TRP296 4.3 63.2 1.0 ND1 A:HIS199 4.3 42.7 1.0 CG A:HIS279 4.3 43.1 1.0 CG A:HIS199 4.4 38.7 1.0 ND1 A:HIS279 4.4 44.5 1.0 O2 A:PEG402 4.5 86.9 1.0 C3 A:PEG402 4.6 87.0 1.0 C2 A:PEG402 4.7 74.2 1.0 C4 A:AKG401 4.8 44.4 1.0 CB A:GLU201 5.0 46.5 1.0

J.A.Hangasky, C.Y.Taabazuing, C.Martin, S.Eron, S.C.Garman, M.J.Knapp. Factor Inhibiting Hif D201E in Complex with Fe, and Alpha-Ketoglutarate To Be Published.