Iron in PDB 5o0t: Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5)

The structure of Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5), PDB code: 5o0t was solved by F.Magnani, S.Nenci, A.Mattevi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.60 / 2.05
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.371, 74.570, 85.120, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.1

The binding sites of Iron atom in the Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5) (pdb code 5o0t). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5), PDB code: 5o0t:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe504 b:24.3 occ:1.00 FE A:HEM504 0.0 24.3 1.0 ND A:HEM504 1.9 26.0 1.0 NA A:HEM504 2.0 25.8 1.0 NE2 A:HIS299 2.0 25.1 1.0 NE2 A:HIS372 2.0 25.4 1.0 NB A:HEM504 2.1 27.2 1.0 NC A:HEM504 2.1 25.1 1.0 C1D A:HEM504 2.9 26.6 1.0 C4D A:HEM504 2.9 26.3 1.0 CE1 A:HIS372 2.9 24.4 1.0 CE1 A:HIS299 3.0 24.2 1.0 C4A A:HEM504 3.0 27.6 1.0 C1A A:HEM504 3.0 26.3 1.0 CD2 A:HIS299 3.0 24.3 1.0 C4B A:HEM504 3.0 26.4 1.0 C1B A:HEM504 3.0 27.6 1.0 C4C A:HEM504 3.1 26.2 1.0 CD2 A:HIS372 3.1 25.9 1.0 C1C A:HEM504 3.1 25.0 1.0 CHD A:HEM504 3.4 25.8 1.0 CHB A:HEM504 3.4 25.9 1.0 CHA A:HEM504 3.4 25.4 1.0 CHC A:HEM504 3.5 25.8 1.0 ND1 A:HIS372 4.1 26.1 1.0 ND1 A:HIS299 4.1 22.6 1.0 C2D A:HEM504 4.2 27.7 1.0 CG A:HIS299 4.2 24.1 1.0 C3D A:HEM504 4.2 29.8 1.0 CG A:HIS372 4.2 27.0 1.0 C3A A:HEM504 4.2 29.7 1.0 C2A A:HEM504 4.2 31.4 1.0 C2B A:HEM504 4.3 27.6 1.0 C3B A:HEM504 4.3 30.8 1.0 C3C A:HEM504 4.3 28.0 1.0 C2C A:HEM504 4.3 27.4 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Trans-Membrane Domain of Cylindrospermum Stagnale Nadph-Oxidase 5 (NOX5) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe505 b:23.5 occ:1.00 FE A:HEM505 0.0 23.5 1.0 NE2 A:HIS385 1.9 26.0 1.0 ND A:HEM505 1.9 24.8 1.0 NE2 A:HIS313 2.0 25.0 1.0 NA A:HEM505 2.0 24.7 1.0 NC A:HEM505 2.1 24.8 1.0 NB A:HEM505 2.1 24.0 1.0 CE1 A:HIS385 2.9 25.8 1.0 CE1 A:HIS313 3.0 23.7 1.0 C1D A:HEM505 3.0 24.9 1.0 C4D A:HEM505 3.0 24.2 1.0 CD2 A:HIS385 3.0 25.4 1.0 C1A A:HEM505 3.0 25.0 1.0 CD2 A:HIS313 3.0 23.7 1.0 C4B A:HEM505 3.0 25.2 1.0 C4C A:HEM505 3.1 24.3 1.0 C4A A:HEM505 3.1 26.6 1.0 C1B A:HEM505 3.1 25.4 1.0 C1C A:HEM505 3.1 24.8 1.0 CHA A:HEM505 3.4 23.5 1.0 CHD A:HEM505 3.4 22.3 1.0 CHC A:HEM505 3.4 22.8 1.0 CHB A:HEM505 3.5 25.0 1.0 ND1 A:HIS385 4.0 24.1 1.0 ND1 A:HIS313 4.1 23.2 1.0 CG A:HIS385 4.1 25.2 1.0 CG A:HIS313 4.1 23.2 1.0 C2A A:HEM505 4.2 26.6 1.0 C2D A:HEM505 4.2 24.6 1.0 C3D A:HEM505 4.3 27.4 1.0 C3A A:HEM505 4.3 26.1 1.0 C3C A:HEM505 4.3 25.3 1.0 C2C A:HEM505 4.3 24.3 1.0 C2B A:HEM505 4.3 25.4 1.0 C3B A:HEM505 4.3 25.5 1.0 CD2 A:HIS317 4.6 25.4 1.0 NE2 A:HIS317 4.7 25.3 1.0

F.Magnani, S.Nenci, E.Millana Fananas, M.Ceccon, E.Romero, M.W.Fraaije, A.Mattevi. Crystal Structures and Atomic Model of Nadph Oxidase. Proc. Natl. Acad. Sci. V. 114 6764 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 28607049
DOI: 10.1073/PNAS.1702293114