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Atomistry » Iron » PDB 5tia-5ufg » 5u6x | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 5tia-5ufg » 5u6x » |
Iron in PDB 5u6x: Cox-1:P6 Complex StructureEnzymatic activity of Cox-1:P6 Complex Structure
All present enzymatic activity of Cox-1:P6 Complex Structure:
1.14.99.1; Protein crystallography data
The structure of Cox-1:P6 Complex Structure, PDB code: 5u6x
was solved by
G.Cingolani,
A.Panella,
M.G.Perrone,
P.Vitale,
W.L.Smith,
A.Scilimati,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5u6x:
The structure of Cox-1:P6 Complex Structure also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Cox-1:P6 Complex Structure
(pdb code 5u6x). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Cox-1:P6 Complex Structure, PDB code: 5u6x: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 5u6xGo back to![]() ![]()
Iron binding site 1 out
of 2 in the Cox-1:P6 Complex Structure
![]() Mono view ![]() Stereo pair view
Iron binding site 2 out of 2 in 5u6xGo back to![]() ![]()
Iron binding site 2 out
of 2 in the Cox-1:P6 Complex Structure
![]() Mono view ![]() Stereo pair view
Reference:
G.Cingolani,
A.Panella,
M.G.Perrone,
P.Vitale,
G.Di Mauro,
C.G.Fortuna,
R.S.Armen,
S.Ferorelli,
W.L.Smith,
A.Scilimati.
Structural Basis For Selective Inhibition of Cyclooxygenase-1 (Cox-1) By Diarylisoxazoles Mofezolac and 3-(5-Chlorofuran-2-Yl)-5-Methyl-4-Phenylisoxazole (P6). Eur J Med Chem V. 138 661 2017.
Page generated: Tue Aug 6 09:47:28 2024
ISSN: ISSN 1768-3254 PubMed: 28710965 DOI: 10.1016/J.EJMECH.2017.06.045 |
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