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Atomistry » Iron » PDB 5utc-5vcp » 5v18 » |
Iron in PDB 5v18: Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]PyridineEnzymatic activity of Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine
All present enzymatic activity of Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine:
1.14.11.29; Protein crystallography data
The structure of Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine, PDB code: 5v18
was solved by
R.J.Skene,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine
(pdb code 5v18). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine, PDB code: 5v18: Iron binding site 1 out of 1 in 5v18Go back to Iron Binding Sites List in 5v18
Iron binding site 1 out
of 1 in the Structure of PHD2 in Complex with 1,2,4-Triazolo-[1,5-A]Pyridine
Mono view Stereo pair view
Reference:
S.Ahmed,
A.Ayscough,
G.R.Barker,
H.E.Canning,
R.Davenport,
R.Downham,
D.Harrison,
K.Jenkins,
N.Kinsella,
D.G.Livermore,
S.Wright,
A.D.Ivetac,
R.Skene,
S.J.Wilkens,
N.A.Webster,
A.G.Hendrick.
1,2,4-Triazolo-[1,5-A]Pyridine Hif Prolylhydroxylase Domain-1 (Phd-1) Inhibitors with A Novel Monodentate Binding Interaction. J. Med. Chem. V. 60 5663 2017.
Page generated: Sun Dec 13 16:14:04 2020
ISSN: ISSN 1520-4804 PubMed: 28594552 DOI: 10.1021/ACS.JMEDCHEM.7B00352 |
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