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Atomistry » Iron » PDB 5vux-5whs » 5w0c | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 5vux-5whs » 5w0c » |
Iron in PDB 5w0c: Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor ComplexEnzymatic activity of Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex
All present enzymatic activity of Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex:
1.14.13.48; 1.14.13.49; 1.14.13.80; 1.14.99.38; Protein crystallography data
The structure of Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex, PDB code: 5w0c
was solved by
E.F.Johnson,
M.-H.Hsu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex
(pdb code 5w0c). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex, PDB code: 5w0c: Iron binding site 1 out of 1 in 5w0cGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Cytochrome P450 (Cyp) 2C9 TCA007 Inhibitor Complex
![]() Mono view ![]() Stereo pair view
Reference:
R.Liu,
X.Lyu,
S.M.Batt,
M.H.Hsu,
M.B.Harbut,
C.Vilcheze,
B.Cheng,
K.Ajayi,
B.Yang,
Y.Yang,
H.Guo,
C.Lin,
F.Gan,
C.Wang,
S.G.Franzblau,
W.R.Jacobs,
G.S.Besra,
E.F.Johnson,
M.Petrassi,
A.K.Chatterjee,
K.Futterer,
F.Wang.
Determinants of the Inhibition of DPRE1 and CYP2C9 By Antitubercular Thiophenes. Angew. Chem. Int. Ed. Engl. V. 56 13011 2017.
Page generated: Tue Aug 6 11:04:26 2024
ISSN: ESSN 1521-3773 PubMed: 28815830 DOI: 10.1002/ANIE.201707324 |
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