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Atomistry » Iron » PDB 6cdk-6cxu » 6cid | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 6cdk-6cxu » 6cid » |
Iron in PDB 6cid: Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-CarboximidamideEnzymatic activity of Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide
All present enzymatic activity of Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide:
1.14.13.39; Protein crystallography data
The structure of Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide, PDB code: 6cid
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6cid:
The structure of Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide
(pdb code 6cid). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide, PDB code: 6cid: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 6cidGo back to Iron Binding Sites List in 6cid
Iron binding site 1 out
of 2 in the Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide
Mono view Stereo pair view
Iron binding site 2 out of 2 in 6cidGo back to Iron Binding Sites List in 6cid
Iron binding site 2 out
of 2 in the Structure of Human Neuronal Nitric Oxide Synthase R354A/G357D Mutant Heme Domain in Complex with N-(1-(Piperidin-4-Yl)Indolin-5-Yl) Thiophene-2-Carboximidamide
Mono view Stereo pair view
Reference:
H.Li,
R.J.Evenson,
G.Chreifi,
R.B.Silverman,
T.L.Poulos.
Structural Basis For Isoform Selective Nitric Oxide Synthase Inhibition By Thiophene-2-Carboximidamides. Biochemistry V. 57 6319 2018.
Page generated: Tue Aug 6 15:00:46 2024
ISSN: ISSN 1520-4995 PubMed: 30335983 DOI: 10.1021/ACS.BIOCHEM.8B00895 |
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