Iron in PDB 6fo2: Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound

All present enzymatic activity of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound:
1.10.2.2;

The binding sites of Iron atom in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound (pdb code 6fo2). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 6 binding sites of Iron where determined in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound, PDB code: 6fo2:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6;

Iron binding site 1 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe501 b:89.1 occ:1.00 FE P:HEM501 0.0 89.1 1.0 ND P:HEM501 1.9 89.1 1.0 NC P:HEM501 2.0 89.1 1.0 NA P:HEM501 2.0 89.1 1.0 HE2 P:HIS182 2.1 79.3 1.0 NB P:HEM501 2.2 89.1 1.0 HE1 P:HIS83 2.2 79.2 1.0 NE2 P:HIS182 2.8 79.3 1.0 CE1 P:HIS83 2.9 79.2 1.0 C4D P:HEM501 2.9 89.1 1.0 C1D P:HEM501 2.9 89.1 1.0 C1A P:HEM501 3.0 89.1 1.0 C4C P:HEM501 3.0 89.1 1.0 C4A P:HEM501 3.0 89.1 1.0 C1C P:HEM501 3.1 89.1 1.0 HD2 P:HIS182 3.1 79.3 1.0 C4B P:HEM501 3.2 89.1 1.0 C1B P:HEM501 3.2 89.1 1.0 CD2 P:HIS182 3.3 79.3 1.0 CHD P:HEM501 3.3 89.1 1.0 CHA P:HEM501 3.3 89.1 1.0 CHB P:HEM501 3.5 89.1 1.0 CHC P:HEM501 3.5 89.1 1.0 NE2 P:HIS83 3.5 79.2 1.0 HA3 P:GLY130 3.7 84.8 1.0 HA2 P:GLY130 3.9 84.8 1.0 ND1 P:HIS83 3.9 79.2 1.0 CE1 P:HIS182 4.0 79.3 1.0 C3D P:HEM501 4.1 89.1 1.0 C2D P:HEM501 4.1 89.1 1.0 HD12 P:LEU133 4.1 79.5 1.0 HD1 P:HIS83 4.2 79.2 1.0 C2A P:HEM501 4.2 89.1 1.0 C3A P:HEM501 4.2 89.1 1.0 C3C P:HEM501 4.2 89.1 1.0 CA P:GLY130 4.2 84.8 1.0 C2C P:HEM501 4.3 89.1 1.0 C3B P:HEM501 4.4 89.1 1.0 C2B P:HEM501 4.4 89.1 1.0 HE1 P:HIS182 4.4 79.3 1.0 CG P:HIS182 4.6 79.3 1.0 HD11 P:LEU133 4.6 79.5 1.0 O P:GLY130 4.7 84.8 1.0 HE21 P:GLN44 4.7 78.5 1.0 CD2 P:HIS83 4.8 79.2 1.0 CD1 P:LEU133 4.8 79.5 1.0 C P:GLY130 4.9 84.8 1.0 ND1 P:HIS182 4.9 79.3 1.0 CG P:HIS83 5.0 79.2 1.0

Iron binding site 2 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe502 b:0.3 occ:1.00 FE P:HEM502 0.0 0.3 1.0 NB P:HEM502 1.9 0.3 1.0 NA P:HEM502 2.0 0.3 1.0 NC P:HEM502 2.0 0.3 1.0 HE2 P:HIS196 2.2 87.0 1.0 ND P:HEM502 2.2 0.3 1.0 HE2 P:HIS97 2.2 85.7 1.0 NE2 P:HIS97 2.7 85.7 1.0 NE2 P:HIS196 2.7 87.0 1.0 C4B P:HEM502 2.9 0.3 1.0 C1B P:HEM502 2.9 0.3 1.0 C4A P:HEM502 2.9 0.3 1.0 C1C P:HEM502 3.0 0.3 1.0 C1A P:HEM502 3.0 0.3 1.0 HE1 P:HIS97 3.1 85.7 1.0 C4C P:HEM502 3.1 0.3 1.0 CE1 P:HIS97 3.1 85.7 1.0 C4D P:HEM502 3.1 0.3 1.0 HD2 P:HIS196 3.1 87.0 1.0 CD2 P:HIS196 3.2 87.0 1.0 C1D P:HEM502 3.2 0.3 1.0 CHC P:HEM502 3.3 0.3 1.0 CHB P:HEM502 3.3 0.3 1.0 CHA P:HEM502 3.4 0.3 1.0 CHD P:HEM502 3.6 0.3 1.0 CE1 P:HIS196 3.8 87.0 1.0 CD2 P:HIS97 3.8 85.7 1.0 HE1 P:HIS196 4.1 87.0 1.0 C3B P:HEM502 4.1 0.3 1.0 C2B P:HEM502 4.1 0.3 1.0 C3A P:HEM502 4.1 0.3 1.0 HD2 P:HIS97 4.1 85.7 1.0 C2A P:HEM502 4.1 0.3 1.0 C2C P:HEM502 4.2 0.3 1.0 ND1 P:HIS97 4.3 85.7 1.0 C3C P:HEM502 4.3 0.3 1.0 HD12 P:LEU37 4.3 84.2 1.0 CG P:HIS196 4.4 87.0 1.0 C3D P:HEM502 4.4 0.3 1.0 C2D P:HEM502 4.4 0.3 1.0 CG P:HIS97 4.6 85.7 1.0 ND1 P:HIS196 4.6 87.0 1.0 HH21 P:ARG100 4.7 88.5 1.0 HA2 P:GLY34 4.8 88.2 1.0 O P:GLY34 4.9 88.2 1.0 HH22 P:ARG100 5.0 88.5 1.0 HD11 P:LEU37 5.0 84.2 1.0

Iron binding site 3 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ Q:Fe501 b:0.1 occ:1.00 FE Q:HEC501 0.0 0.1 1.0 NA Q:HEC501 1.9 0.1 1.0 ND Q:HEC501 2.0 0.1 1.0 NC Q:HEC501 2.1 0.1 1.0 NB Q:HEC501 2.1 0.1 1.0 HE1 Q:MET160 2.3 0.3 1.0 HE1 Q:HIS41 2.5 95.3 1.0 NE2 Q:HIS41 2.6 95.3 1.0 CE1 Q:HIS41 2.9 95.3 1.0 CE Q:MET160 2.9 0.3 1.0 SD Q:MET160 2.9 0.3 1.0 C1A Q:HEC501 3.0 0.1 1.0 C4A Q:HEC501 3.0 0.1 1.0 C4D Q:HEC501 3.0 0.1 1.0 C1D Q:HEC501 3.0 0.1 1.0 C1B Q:HEC501 3.0 0.1 1.0 C4C Q:HEC501 3.0 0.1 1.0 C1C Q:HEC501 3.1 0.1 1.0 C4B Q:HEC501 3.2 0.1 1.0 CHA Q:HEC501 3.3 0.1 1.0 HE3 Q:MET160 3.4 0.3 1.0 CHB Q:HEC501 3.4 0.1 1.0 CHD Q:HEC501 3.4 0.1 1.0 CHC Q:HEC501 3.5 0.1 1.0 HE2 Q:MET160 3.7 0.3 1.0 CD2 Q:HIS41 4.0 95.3 1.0 C3A Q:HEC501 4.2 0.1 1.0 C2A Q:HEC501 4.2 0.1 1.0 ND1 Q:HIS41 4.2 95.3 1.0 C2B Q:HEC501 4.2 0.1 1.0 C2D Q:HEC501 4.2 0.1 1.0 C3D Q:HEC501 4.2 0.1 1.0 C3B Q:HEC501 4.3 0.1 1.0 C3C Q:HEC501 4.3 0.1 1.0 C2C Q:HEC501 4.3 0.1 1.0 HD2 Q:HIS41 4.5 95.3 1.0 HB3 Q:PRO110 4.6 98.5 1.0 CG Q:MET160 4.7 0.3 1.0 CG Q:HIS41 4.7 95.3 1.0 HD11 Q:LEU113 4.7 96.3 1.0 HD1 Q:HIS41 4.8 95.3 1.0 HG2 Q:MET160 4.9 0.3 1.0 HD21 Q:LEU113 5.0 96.3 1.0 HG3 Q:PRO163 5.0 0.5 1.0

Iron binding site 4 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe501 b:94.6 occ:1.00 FE C:HEM501 0.0 94.6 1.0 ND C:HEM501 1.9 94.6 1.0 NC C:HEM501 2.0 94.6 1.0 NA C:HEM501 2.0 94.6 1.0 HE2 C:HIS182 2.1 81.7 1.0 NB C:HEM501 2.2 94.6 1.0 HE1 C:HIS83 2.2 82.6 1.0 NE2 C:HIS182 2.8 81.7 1.0 CE1 C:HIS83 2.9 82.6 1.0 C4D C:HEM501 2.9 94.6 1.0 C1D C:HEM501 2.9 94.6 1.0 C1A C:HEM501 3.0 94.6 1.0 C4C C:HEM501 3.0 94.6 1.0 C4A C:HEM501 3.0 94.6 1.0 C1C C:HEM501 3.1 94.6 1.0 HD2 C:HIS182 3.1 81.7 1.0 C4B C:HEM501 3.2 94.6 1.0 C1B C:HEM501 3.2 94.6 1.0 CD2 C:HIS182 3.3 81.7 1.0 CHD C:HEM501 3.3 94.6 1.0 CHA C:HEM501 3.3 94.6 1.0 CHB C:HEM501 3.5 94.6 1.0 CHC C:HEM501 3.5 94.6 1.0 NE2 C:HIS83 3.5 82.6 1.0 HA3 C:GLY130 3.7 86.1 1.0 HA2 C:GLY130 3.9 86.1 1.0 ND1 C:HIS83 3.9 82.6 1.0 CE1 C:HIS182 4.0 81.7 1.0 C3D C:HEM501 4.1 94.6 1.0 C2D C:HEM501 4.1 94.6 1.0 HD12 C:LEU133 4.1 82.6 1.0 HD1 C:HIS83 4.2 82.6 1.0 C2A C:HEM501 4.2 94.6 1.0 C3A C:HEM501 4.2 94.6 1.0 C3C C:HEM501 4.2 94.6 1.0 CA C:GLY130 4.3 86.1 1.0 C2C C:HEM501 4.3 94.6 1.0 C3B C:HEM501 4.4 94.6 1.0 C2B C:HEM501 4.4 94.6 1.0 HE1 C:HIS182 4.4 81.7 1.0 CG C:HIS182 4.6 81.7 1.0 HD11 C:LEU133 4.6 82.6 1.0 O C:GLY130 4.7 86.1 1.0 HE21 C:GLN44 4.7 81.7 1.0 CD2 C:HIS83 4.8 82.6 1.0 CD1 C:LEU133 4.8 82.6 1.0 C C:GLY130 4.9 86.1 1.0 ND1 C:HIS182 4.9 81.7 1.0 CG C:HIS83 4.9 82.6 1.0

Iron binding site 5 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe502 b:0.2 occ:1.00 FE C:HEM502 0.0 0.2 1.0 NB C:HEM502 1.9 0.2 1.0 NA C:HEM502 2.0 0.2 1.0 NC C:HEM502 2.0 0.2 1.0 HE2 C:HIS196 2.2 88.0 1.0 ND C:HEM502 2.2 0.2 1.0 HE2 C:HIS97 2.2 88.7 1.0 NE2 C:HIS97 2.7 88.7 1.0 NE2 C:HIS196 2.7 88.0 1.0 C4B C:HEM502 2.9 0.2 1.0 C1B C:HEM502 2.9 0.2 1.0 C4A C:HEM502 2.9 0.2 1.0 C1C C:HEM502 3.0 0.2 1.0 C1A C:HEM502 3.0 0.2 1.0 HE1 C:HIS97 3.1 88.7 1.0 CE1 C:HIS97 3.1 88.7 1.0 C4D C:HEM502 3.1 0.2 1.0 C4C C:HEM502 3.1 0.2 1.0 HD2 C:HIS196 3.1 88.0 1.0 CD2 C:HIS196 3.2 88.0 1.0 C1D C:HEM502 3.2 0.2 1.0 CHC C:HEM502 3.3 0.2 1.0 CHB C:HEM502 3.3 0.2 1.0 CHA C:HEM502 3.4 0.2 1.0 CHD C:HEM502 3.6 0.2 1.0 CD2 C:HIS97 3.8 88.7 1.0 CE1 C:HIS196 3.8 88.0 1.0 HE1 C:HIS196 4.1 88.0 1.0 C3B C:HEM502 4.1 0.2 1.0 C3A C:HEM502 4.1 0.2 1.0 C2B C:HEM502 4.1 0.2 1.0 HD2 C:HIS97 4.1 88.7 1.0 C2A C:HEM502 4.1 0.2 1.0 C2C C:HEM502 4.2 0.2 1.0 ND1 C:HIS97 4.3 88.7 1.0 C3C C:HEM502 4.3 0.2 1.0 HD12 C:LEU37 4.3 87.7 1.0 C3D C:HEM502 4.4 0.2 1.0 CG C:HIS196 4.4 88.0 1.0 C2D C:HEM502 4.4 0.2 1.0 CG C:HIS97 4.6 88.7 1.0 ND1 C:HIS196 4.6 88.0 1.0 HH21 C:ARG100 4.7 90.8 1.0 HA2 C:GLY34 4.8 91.7 1.0 O C:GLY34 4.9 91.7 1.0 HH22 C:ARG100 5.0 90.8 1.0 HD11 C:LEU37 5.0 87.7 1.0

Iron binding site 6 out of 6 in the Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryoem Structure of Bovine Cytochrome BC1 with No Ligand Bound within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe501 b:50.7 occ:1.00 FE D:HEC501 0.0 50.7 1.0 NA D:HEC501 1.9 50.7 1.0 ND D:HEC501 2.0 50.7 1.0 NC D:HEC501 2.1 50.7 1.0 NB D:HEC501 2.1 50.7 1.0 HE1 D:MET160 2.2 0.7 1.0 NE2 D:HIS41 2.3 95.5 1.0 HE1 D:HIS41 2.5 95.5 1.0 CE1 D:HIS41 2.7 95.5 1.0 C1A D:HEC501 2.9 50.7 1.0 C4D D:HEC501 3.0 50.7 1.0 C1D D:HEC501 3.0 50.7 1.0 CE D:MET160 3.0 0.7 1.0 C4A D:HEC501 3.0 50.7 1.0 C4C D:HEC501 3.0 50.7 1.0 C1B D:HEC501 3.1 50.7 1.0 C4B D:HEC501 3.1 50.7 1.0 C1C D:HEC501 3.1 50.7 1.0 SD D:MET160 3.2 0.7 1.0 CHA D:HEC501 3.2 50.7 1.0 CHD D:HEC501 3.4 50.7 1.0 CHB D:HEC501 3.4 50.7 1.0 HE2 D:MET160 3.5 0.7 1.0 CHC D:HEC501 3.5 50.7 1.0 CD2 D:HIS41 3.6 95.5 1.0 HE3 D:MET160 3.7 0.7 1.0 ND1 D:HIS41 4.0 95.5 1.0 HD2 D:HIS41 4.1 95.5 1.0 C2A D:HEC501 4.1 50.7 1.0 C3D D:HEC501 4.2 50.7 1.0 C3A D:HEC501 4.2 50.7 1.0 C2D D:HEC501 4.2 50.7 1.0 C3C D:HEC501 4.2 50.7 1.0 C2B D:HEC501 4.3 50.7 1.0 C2C D:HEC501 4.3 50.7 1.0 C3B D:HEC501 4.3 50.7 1.0 CG D:HIS41 4.4 95.5 1.0 HD11 D:LEU113 4.5 96.2 1.0 HB3 D:PRO110 4.6 98.8 1.0 HD1 D:HIS41 4.6 95.5 1.0 HG3 D:PRO163 4.9 0.4 1.0 HD21 D:LEU113 4.9 96.2 1.0 HB3 D:PRO163 5.0 0.4 1.0 CG D:MET160 5.0 0.7 1.0

K.Amporndanai, R.M.Johnson, P.M.O'neill, C.W.G.Fishwick, A.H.Jamson, S.Rawson, S.P.Muench, S.S.Hasnain, S.V.Antonyuk. X-Ray and Cryo-Em Structures of Inhibitor-Bound CYTOCHROMEBC1COMPLEXES For Structure-Based Drug Discovery. Iucrj V. 5 200 2018.
ISSN: ESSN 2052-2525
PubMed: 29765610
DOI: 10.1107/S2052252518001616