Iron in PDB 6g72: Mouse Mitochondrial Complex I in the Deactive State

All present enzymatic activity of Mouse Mitochondrial Complex I in the Deactive State:
1.6.5.3; 1.6.99.3;

The structure of Mouse Mitochondrial Complex I in the Deactive State also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Mouse Mitochondrial Complex I in the Deactive State (pdb code 6g72). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Mouse Mitochondrial Complex I in the Deactive State, PDB code: 6g72:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:49.4 occ:1.00 FE1 B:SF4201 0.0 49.4 1.0 SG B:CYS129 2.2 50.2 1.0 S3 B:SF4201 2.3 49.4 1.0 S4 B:SF4201 2.3 49.4 1.0 S2 B:SF4201 2.3 49.4 1.0 FE4 B:SF4201 2.7 49.4 1.0 FE2 B:SF4201 2.7 49.4 1.0 FE3 B:SF4201 2.7 49.4 1.0 CB B:CYS129 3.2 50.2 1.0 S1 B:SF4201 3.9 49.4 1.0 CQ2 D:2MR85 4.0 52.5 1.0 CG2 B:THR101 4.3 52.9 1.0 N B:CYS129 4.3 50.2 1.0 CA B:CYS129 4.3 50.2 1.0 NH2 D:2MR85 4.4 52.5 1.0 OG B:SER128 4.6 48.9 1.0 SG B:CYS159 4.7 49.0 1.0 O B:CYS159 4.7 49.0 1.0 SG B:CYS65 4.8 53.7 1.0 N B:THR101 4.8 52.9 1.0 SG B:CYS64 4.9 52.2 1.0

Iron binding site 2 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:49.4 occ:1.00 FE2 B:SF4201 0.0 49.4 1.0 S4 B:SF4201 2.3 49.4 1.0 S3 B:SF4201 2.3 49.4 1.0 S1 B:SF4201 2.3 49.4 1.0 SG B:CYS65 2.3 53.7 1.0 FE4 B:SF4201 2.7 49.4 1.0 FE1 B:SF4201 2.7 49.4 1.0 FE3 B:SF4201 2.7 49.4 1.0 O B:CYS159 2.8 49.0 1.0 CB B:CYS65 3.0 53.7 1.0 N B:CYS65 3.6 53.7 1.0 CA B:CYS65 3.7 53.7 1.0 C B:CYS159 3.8 49.0 1.0 S2 B:SF4201 3.9 49.4 1.0 CA B:CYS159 4.6 49.0 1.0 SG B:CYS129 4.6 50.2 1.0 CA B:GLY127 4.6 49.6 1.0 N B:PRO160 4.7 48.7 1.0 SG B:CYS64 4.7 52.2 1.0 SG B:CYS159 4.7 49.0 1.0 CB B:CYS64 4.7 52.2 1.0 C B:CYS64 4.8 52.2 1.0 CB B:CYS129 4.8 50.2 1.0 CA B:GLY100 4.8 51.3 1.0 CA B:PRO160 5.0 48.7 1.0

Iron binding site 3 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:49.4 occ:1.00 FE3 B:SF4201 0.0 49.4 1.0 S1 B:SF4201 2.3 49.4 1.0 S2 B:SF4201 2.3 49.4 1.0 S4 B:SF4201 2.3 49.4 1.0 SG B:CYS64 2.3 52.2 1.0 FE4 B:SF4201 2.7 49.4 1.0 FE1 B:SF4201 2.7 49.4 1.0 FE2 B:SF4201 2.7 49.4 1.0 CB B:CYS64 3.2 52.2 1.0 NE2 D:HIS190 3.5 51.0 1.0 S3 B:SF4201 3.9 49.4 1.0 N B:CYS64 4.0 52.2 1.0 N B:CYS65 4.0 53.7 1.0 CE1 D:HIS190 4.1 51.0 1.0 CA B:CYS64 4.1 52.2 1.0 CG D:ARG105 4.2 50.8 1.0 NE D:ARG105 4.5 50.8 1.0 CD2 D:HIS190 4.5 51.0 1.0 NH2 D:2MR85 4.5 52.5 1.0 C B:CYS64 4.6 52.2 1.0 SG B:CYS159 4.6 49.0 1.0 O B:CYS159 4.7 49.0 1.0 CB B:ALA63 4.7 53.1 1.0 SG B:CYS65 4.8 53.7 1.0 CB B:CYS65 4.9 53.7 1.0 SG B:CYS129 4.9 50.2 1.0 CQ2 D:2MR85 4.9 52.5 1.0 CD D:ARG105 4.9 50.8 1.0 CA B:CYS65 5.0 53.7 1.0

Iron binding site 4 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:49.4 occ:1.00 FE4 B:SF4201 0.0 49.4 1.0 SG B:CYS159 2.2 49.0 1.0 S1 B:SF4201 2.3 49.4 1.0 S2 B:SF4201 2.3 49.4 1.0 S3 B:SF4201 2.3 49.4 1.0 FE1 B:SF4201 2.7 49.4 1.0 FE2 B:SF4201 2.7 49.4 1.0 FE3 B:SF4201 2.7 49.4 1.0 O B:CYS159 3.0 49.0 1.0 C B:CYS159 3.2 49.0 1.0 CB B:CYS159 3.3 49.0 1.0 CA B:CYS159 3.4 49.0 1.0 NH2 D:ARG105 3.8 50.8 1.0 S4 B:SF4201 3.9 49.4 1.0 NE2 D:HIS190 3.9 51.0 1.0 N B:PRO160 4.0 48.7 1.0 CD2 D:HIS190 4.1 51.0 1.0 NE D:ARG105 4.3 50.8 1.0 OG B:SER128 4.3 48.9 1.0 CZ D:ARG105 4.4 50.8 1.0 CD B:PRO160 4.5 48.7 1.0 SG B:CYS129 4.5 50.2 1.0 SG B:CYS65 4.7 53.7 1.0 CE1 D:HIS190 4.7 51.0 1.0 SG B:CYS64 4.8 52.2 1.0 CD1 I:ILE119 4.9 47.6 1.0 N B:CYS159 4.9 49.0 1.0 CA B:PRO160 4.9 48.7 1.0

Iron binding site 5 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe301 b:90.4 occ:1.00 FE1 E:FES301 0.0 90.4 1.0 SG E:CYS103 2.2 82.8 1.0 S2 E:FES301 2.2 90.4 1.0 S1 E:FES301 2.2 90.4 1.0 SG E:CYS108 2.3 83.5 1.0 FE2 E:FES301 2.7 90.4 1.0 CB E:CYS103 3.2 82.8 1.0 CB E:CYS108 3.3 83.5 1.0 OG1 E:THR105 3.4 80.9 1.0 CA E:CYS148 4.1 85.0 1.0 CB E:CYS148 4.3 85.0 1.0 SG E:CYS148 4.3 85.0 1.0 CA E:CYS144 4.3 80.9 1.0 O E:GLU143 4.3 78.5 1.0 N E:CYS108 4.5 83.5 1.0 N E:LEU145 4.5 84.2 1.0 CA E:CYS108 4.5 83.5 1.0 CG E:PRO107 4.5 83.2 1.0 CA E:CYS103 4.6 82.8 1.0 SG E:CYS144 4.6 80.9 1.0 O E:ALA151 4.7 86.5 1.0 CB E:THR105 4.8 80.9 1.0 CB E:CYS144 4.8 80.9 1.0 N E:CYS148 4.9 85.0 1.0 CD E:PRO107 4.9 83.2 1.0 C E:CYS144 4.9 80.9 1.0 N E:THR105 4.9 80.9 1.0

Iron binding site 6 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe301 b:90.4 occ:1.00 FE2 E:FES301 0.0 90.4 1.0 SG E:CYS148 2.2 85.0 1.0 S2 E:FES301 2.2 90.4 1.0 S1 E:FES301 2.2 90.4 1.0 SG E:CYS144 2.3 80.9 1.0 FE1 E:FES301 2.7 90.4 1.0 CB E:CYS148 3.2 85.0 1.0 CB E:CYS144 3.3 80.9 1.0 N E:LEU145 3.4 84.2 1.0 CA E:CYS144 3.6 80.9 1.0 CA E:CYS148 3.7 85.0 1.0 N E:GLY146 3.8 83.8 1.0 N E:CYS148 4.0 85.0 1.0 CA F:PRO102 4.0 81.4 1.0 C E:CYS144 4.0 80.9 1.0 OG1 E:THR105 4.1 80.9 1.0 SG E:CYS103 4.3 82.8 1.0 CB F:PRO102 4.4 81.4 1.0 SG E:CYS108 4.5 83.5 1.0 CA E:LEU145 4.5 84.2 1.0 C E:LEU145 4.5 84.2 1.0 N F:GLY103 4.5 84.2 1.0 CA E:GLY146 4.5 83.8 1.0 C F:PRO102 4.6 81.4 1.0 C E:GLY146 4.6 83.8 1.0 O F:GLU101 4.7 79.0 1.0 C E:ALA147 4.8 85.4 1.0 N E:ALA147 4.9 85.4 1.0 N E:CYS144 4.9 80.9 1.0 O E:GLU143 4.9 78.5 1.0 O E:GLY146 5.0 83.8 1.0

Iron binding site 7 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe502 b:61.9 occ:1.00 FE1 F:SF4502 0.0 61.9 1.0 SG F:CYS362 2.1 60.1 1.0 S2 F:SF4502 2.3 61.9 1.0 S4 F:SF4502 2.3 61.9 1.0 S3 F:SF4502 2.3 61.9 1.0 FE3 F:SF4502 2.7 61.9 1.0 FE4 F:SF4502 2.7 61.9 1.0 FE2 F:SF4502 2.7 61.9 1.0 CB F:CYS362 3.0 60.1 1.0 N F:CYS362 3.6 60.1 1.0 S1 F:SF4502 3.9 61.9 1.0 CA F:CYS362 3.9 60.1 1.0 CB F:ILE404 4.2 59.2 1.0 CB F:CYS365 4.3 59.6 1.0 N F:ILE404 4.3 59.2 1.0 CD1 F:ILE404 4.4 59.2 1.0 SG F:CYS359 4.5 63.0 1.0 SG F:CYS365 4.5 59.6 1.0 N F:CYS405 4.5 63.4 1.0 CG1 F:ILE404 4.6 59.2 1.0 SG F:CYS405 4.7 63.4 1.0 C F:GLN361 4.8 59.0 1.0 CA F:ILE404 4.8 59.2 1.0 CB F:THR403 4.8 58.2 1.0 CB F:GLN361 4.9 59.0 1.0 N F:GLN361 5.0 59.0 1.0

Iron binding site 8 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe502 b:61.9 occ:1.00 FE2 F:SF4502 0.0 61.9 1.0 SG F:CYS365 2.2 59.6 1.0 S1 F:SF4502 2.3 61.9 1.0 S3 F:SF4502 2.3 61.9 1.0 S4 F:SF4502 2.3 61.9 1.0 FE4 F:SF4502 2.7 61.9 1.0 FE1 F:SF4502 2.7 61.9 1.0 FE3 F:SF4502 2.7 61.9 1.0 CB F:CYS365 3.1 59.6 1.0 CB F:SER358 3.7 64.8 1.0 S2 F:SF4502 3.9 61.9 1.0 CD2 F:LEU407 4.4 67.2 1.0 N F:CYS359 4.4 63.0 1.0 OG F:SER358 4.4 64.8 1.0 CA F:CYS365 4.5 59.6 1.0 SG F:CYS405 4.6 63.4 1.0 SG F:CYS362 4.6 60.1 1.0 SG F:CYS359 4.6 63.0 1.0 CA F:SER358 4.6 64.8 1.0 CB F:CYS362 4.6 60.1 1.0 C F:CYS365 4.8 59.6 1.0 N F:GLY360 4.8 61.1 1.0 CD1 F:LEU407 4.9 67.2 1.0 CB F:LEU407 4.9 67.2 1.0 C F:SER358 4.9 64.8 1.0 O F:CYS365 5.0 59.6 1.0 CG F:LEU407 5.0 67.2 1.0

Iron binding site 9 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe502 b:61.9 occ:1.00 FE3 F:SF4502 0.0 61.9 1.0 SG F:CYS405 2.2 63.4 1.0 S4 F:SF4502 2.3 61.9 1.0 S2 F:SF4502 2.3 61.9 1.0 S1 F:SF4502 2.3 61.9 1.0 FE1 F:SF4502 2.7 61.9 1.0 FE2 F:SF4502 2.7 61.9 1.0 FE4 F:SF4502 2.7 61.9 1.0 CB F:CYS405 3.3 63.4 1.0 CD1 F:ILE185 3.7 68.3 1.0 S3 F:SF4502 3.9 61.9 1.0 N F:CYS405 3.9 63.4 1.0 CA F:CYS405 4.1 63.4 1.0 CB F:LEU407 4.3 67.2 1.0 O F:CYS405 4.5 63.4 1.0 C F:CYS405 4.5 63.4 1.0 CG1 F:ILE185 4.6 68.3 1.0 SG F:CYS362 4.6 60.1 1.0 CG F:PRO203 4.7 64.4 1.0 SG F:CYS365 4.7 59.6 1.0 CD1 F:LEU407 4.9 67.2 1.0 SG F:CYS359 4.9 63.0 1.0

Iron binding site 10 out of 28 in the Mouse Mitochondrial Complex I in the Deactive State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Mouse Mitochondrial Complex I in the Deactive State within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe502 b:61.9 occ:1.00 FE4 F:SF4502 0.0 61.9 1.0 SG F:CYS359 2.2 63.0 1.0 S3 F:SF4502 2.3 61.9 1.0 S1 F:SF4502 2.3 61.9 1.0 S2 F:SF4502 2.3 61.9 1.0 FE1 F:SF4502 2.7 61.9 1.0 FE2 F:SF4502 2.7 61.9 1.0 FE3 F:SF4502 2.7 61.9 1.0 CB F:CYS359 3.3 63.0 1.0 N F:CYS359 3.6 63.0 1.0 S4 F:SF4502 3.9 61.9 1.0 CA F:CYS359 3.9 63.0 1.0 N F:GLY360 4.0 61.1 1.0 CD F:PRO203 4.2 64.4 1.0 N F:GLN361 4.3 59.0 1.0 CB F:GLN361 4.4 59.0 1.0 C F:CYS359 4.5 63.0 1.0 CD1 F:ILE185 4.6 68.3 1.0 N F:CYS362 4.7 60.1 1.0 CG1 F:ILE185 4.7 68.3 1.0 SG F:CYS362 4.7 60.1 1.0 C F:SER358 4.7 64.8 1.0 CG F:PRO203 4.7 64.4 1.0 OE1 F:GLN361 4.8 59.0 1.0 SG F:CYS365 4.8 59.6 1.0 SG F:CYS405 4.9 63.4 1.0 CB F:SER358 4.9 64.8 1.0 CA F:GLN361 4.9 59.0 1.0

A.A.Agip, J.N.Blaza, H.R.Bridges, C.Viscomi, S.Rawson, S.P.Muench, J.Hirst. Cryo-Em Structures of Complex I From Mouse Heart Mitochondria in Two Biochemically Defined States. Nat. Struct. Mol. Biol. V. 25 548 2018.
ISSN: ESSN 1545-9985
PubMed: 29915388
DOI: 10.1038/S41594-018-0073-1