Iron in PDB 6hd1: Human STEAP4 Bound to Nadph, Fad and Heme.

The binding sites of Iron atom in the Human STEAP4 Bound to Nadph, Fad and Heme. (pdb code 6hd1). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 3 binding sites of Iron where determined in the Human STEAP4 Bound to Nadph, Fad and Heme., PDB code: 6hd1:
Jump to Iron binding site number: 1; 2; 3;

Iron binding site 1 out of 3 in the Human STEAP4 Bound to Nadph, Fad and Heme.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human STEAP4 Bound to Nadph, Fad and Heme. within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe502 b:67.7 occ:1.00 FE C:HEM502 0.0 67.7 1.0 ND C:HEM502 1.8 67.7 1.0 NE2 C:HIS304 2.0 63.6 1.0 NA C:HEM502 2.0 67.7 1.0 NE2 C:HIS397 2.0 73.6 1.0 NC C:HEM502 2.1 67.7 1.0 NB C:HEM502 2.1 67.7 1.0 CD2 C:HIS397 2.7 73.6 1.0 C4D C:HEM502 2.8 67.7 1.0 C1D C:HEM502 2.8 67.7 1.0 C1A C:HEM502 2.9 67.7 1.0 CE1 C:HIS304 2.9 63.6 1.0 CD2 C:HIS304 3.0 63.6 1.0 C4C C:HEM502 3.0 67.7 1.0 C4A C:HEM502 3.0 67.7 1.0 C1B C:HEM502 3.0 67.7 1.0 C4B C:HEM502 3.1 67.7 1.0 C1C C:HEM502 3.1 67.7 1.0 CE1 C:HIS397 3.1 73.6 1.0 CHA C:HEM502 3.3 67.7 1.0 CHD C:HEM502 3.3 67.7 1.0 CHB C:HEM502 3.4 67.7 1.0 CHC C:HEM502 3.5 67.7 1.0 CG C:HIS397 3.9 73.6 1.0 ND1 C:HIS304 4.0 63.6 1.0 C3D C:HEM502 4.1 67.7 1.0 C2D C:HEM502 4.1 67.7 1.0 CG C:HIS304 4.1 63.6 1.0 ND1 C:HIS397 4.1 73.6 1.0 C2A C:HEM502 4.1 67.7 1.0 C3A C:HEM502 4.2 67.7 1.0 C3C C:HEM502 4.2 67.7 1.0 C2C C:HEM502 4.2 67.7 1.0 C2B C:HEM502 4.2 67.7 1.0 C3B C:HEM502 4.3 67.7 1.0

Iron binding site 2 out of 3 in the Human STEAP4 Bound to Nadph, Fad and Heme.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human STEAP4 Bound to Nadph, Fad and Heme. within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe502 b:66.7 occ:1.00 FE A:HEM502 0.0 66.7 1.0 ND A:HEM502 1.8 66.7 1.0 NE2 A:HIS304 2.0 64.0 1.0 NA A:HEM502 2.0 66.7 1.0 NE2 A:HIS397 2.0 71.9 1.0 NC A:HEM502 2.1 66.7 1.0 NB A:HEM502 2.1 66.7 1.0 CD2 A:HIS397 2.7 71.9 1.0 C4D A:HEM502 2.8 66.7 1.0 C1D A:HEM502 2.8 66.7 1.0 C1A A:HEM502 2.9 66.7 1.0 CE1 A:HIS304 2.9 64.0 1.0 CD2 A:HIS304 3.0 64.0 1.0 C4C A:HEM502 3.0 66.7 1.0 C4A A:HEM502 3.0 66.7 1.0 C1B A:HEM502 3.0 66.7 1.0 C4B A:HEM502 3.1 66.7 1.0 C1C A:HEM502 3.1 66.7 1.0 CE1 A:HIS397 3.1 71.9 1.0 CHA A:HEM502 3.3 66.7 1.0 CHD A:HEM502 3.3 66.7 1.0 CHB A:HEM502 3.4 66.7 1.0 CHC A:HEM502 3.5 66.7 1.0 CG A:HIS397 3.9 71.9 1.0 ND1 A:HIS304 4.0 64.0 1.0 C3D A:HEM502 4.1 66.7 1.0 C2D A:HEM502 4.1 66.7 1.0 CG A:HIS304 4.1 64.0 1.0 ND1 A:HIS397 4.1 71.9 1.0 C2A A:HEM502 4.1 66.7 1.0 C3A A:HEM502 4.2 66.7 1.0 C3C A:HEM502 4.2 66.7 1.0 C2C A:HEM502 4.2 66.7 1.0 C2B A:HEM502 4.2 66.7 1.0 C3B A:HEM502 4.3 66.7 1.0

Iron binding site 3 out of 3 in the Human STEAP4 Bound to Nadph, Fad and Heme.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human STEAP4 Bound to Nadph, Fad and Heme. within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe502 b:67.4 occ:1.00 FE B:HEM502 0.0 67.4 1.0 ND B:HEM502 1.8 67.4 1.0 NE2 B:HIS304 2.0 63.8 1.0 NA B:HEM502 2.0 67.4 1.0 NE2 B:HIS397 2.0 72.8 1.0 NC B:HEM502 2.1 67.4 1.0 NB B:HEM502 2.1 67.4 1.0 CD2 B:HIS397 2.7 72.8 1.0 C4D B:HEM502 2.8 67.4 1.0 C1D B:HEM502 2.8 67.4 1.0 C1A B:HEM502 2.9 67.4 1.0 CE1 B:HIS304 2.9 63.8 1.0 CD2 B:HIS304 3.0 63.8 1.0 C4C B:HEM502 3.0 67.4 1.0 C4A B:HEM502 3.0 67.4 1.0 C1B B:HEM502 3.0 67.4 1.0 C4B B:HEM502 3.1 67.4 1.0 C1C B:HEM502 3.1 67.4 1.0 CE1 B:HIS397 3.1 72.8 1.0 CHA B:HEM502 3.3 67.4 1.0 CHD B:HEM502 3.3 67.4 1.0 CHB B:HEM502 3.4 67.4 1.0 CHC B:HEM502 3.5 67.4 1.0 CG B:HIS397 3.9 72.8 1.0 ND1 B:HIS304 4.0 63.8 1.0 C3D B:HEM502 4.1 67.4 1.0 C2D B:HEM502 4.1 67.4 1.0 CG B:HIS304 4.1 63.8 1.0 ND1 B:HIS397 4.1 72.8 1.0 C2A B:HEM502 4.1 67.4 1.0 C3A B:HEM502 4.2 67.4 1.0 C3C B:HEM502 4.2 67.4 1.0 C2C B:HEM502 4.2 67.4 1.0 C2B B:HEM502 4.2 67.4 1.0 C3B B:HEM502 4.3 67.4 1.0

W.Oosterheert, L.S.Van Bezouwen, R.N.P.Rodenburg, J.Granneman, F.Forster, A.Mattevi, P.Gros. Cryo-Em Structures of Human STEAP4 Reveal Mechanism of Iron(III) Reduction. Nat Commun V. 9 4337 2018.
ISSN: ESSN 2041-1723
PubMed: 30337524
DOI: 10.1038/S41467-018-06817-7