Iron in PDB 6hu9: III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae

All present enzymatic activity of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae:
1.10.2.2; 1.9.3.1;

The structure of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Zinc	(Zn)	2 atoms
Calcium	(Ca)	2 atoms
Copper	(Cu)	6 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Iron atom in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae (pdb code 6hu9). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 14 binding sites of Iron where determined in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae, PDB code: 6hu9:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe601 b:41.4 occ:1.00 FE C:HEM601 0.0 41.4 1.0 ND C:HEM601 1.9 41.4 1.0 NA C:HEM601 2.0 41.4 1.0 NE2 C:HIS82 2.0 45.2 1.0 NE2 C:HIS183 2.0 42.7 1.0 NC C:HEM601 2.1 41.4 1.0 NB C:HEM601 2.1 41.4 1.0 CE1 C:HIS183 2.5 42.7 1.0 C1D C:HEM601 2.9 41.4 1.0 CD2 C:HIS82 2.9 45.2 1.0 C4D C:HEM601 2.9 41.4 1.0 C1A C:HEM601 2.9 41.4 1.0 C4C C:HEM601 3.0 41.4 1.0 C4A C:HEM601 3.0 41.4 1.0 CE1 C:HIS82 3.1 45.2 1.0 C1B C:HEM601 3.1 41.4 1.0 C4B C:HEM601 3.1 41.4 1.0 C1C C:HEM601 3.1 41.4 1.0 CD2 C:HIS183 3.3 42.7 1.0 CHA C:HEM601 3.3 41.4 1.0 CHD C:HEM601 3.3 41.4 1.0 CHB C:HEM601 3.5 41.4 1.0 CHC C:HEM601 3.5 41.4 1.0 ND1 C:HIS183 3.8 42.7 1.0 CG C:HIS82 4.1 45.2 1.0 C2D C:HEM601 4.1 41.4 1.0 ND1 C:HIS82 4.1 45.2 1.0 C2A C:HEM601 4.1 41.4 1.0 C3D C:HEM601 4.1 41.4 1.0 C3A C:HEM601 4.2 41.4 1.0 CG C:HIS183 4.2 42.7 1.0 C3C C:HEM601 4.2 41.4 1.0 C2C C:HEM601 4.2 41.4 1.0 C2B C:HEM601 4.3 41.4 1.0 C3B C:HEM601 4.3 41.4 1.0 CA C:GLY131 4.7 46.2 1.0

Iron binding site 2 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe602 b:40.1 occ:1.00 FE C:HEM602 0.0 40.1 1.0 ND C:HEM602 1.9 40.1 1.0 NA C:HEM602 2.0 40.1 1.0 NE2 C:HIS96 2.0 44.4 1.0 NE2 C:HIS197 2.0 44.3 1.0 NC C:HEM602 2.1 40.1 1.0 NB C:HEM602 2.1 40.1 1.0 CD2 C:HIS96 2.8 44.4 1.0 C4D C:HEM602 2.9 40.1 1.0 C1D C:HEM602 2.9 40.1 1.0 CD2 C:HIS197 2.9 44.3 1.0 C1A C:HEM602 2.9 40.1 1.0 C4C C:HEM602 3.0 40.1 1.0 CE1 C:HIS197 3.0 44.3 1.0 C4A C:HEM602 3.0 40.1 1.0 C1B C:HEM602 3.1 40.1 1.0 C4B C:HEM602 3.1 40.1 1.0 C1C C:HEM602 3.1 40.1 1.0 CE1 C:HIS96 3.1 44.4 1.0 CHA C:HEM602 3.3 40.1 1.0 CHD C:HEM602 3.3 40.1 1.0 CHB C:HEM602 3.5 40.1 1.0 CHC C:HEM602 3.5 40.1 1.0 CG C:HIS96 4.0 44.4 1.0 CG C:HIS197 4.1 44.3 1.0 ND1 C:HIS197 4.1 44.3 1.0 C2D C:HEM602 4.1 40.1 1.0 C3D C:HEM602 4.1 40.1 1.0 ND1 C:HIS96 4.1 44.4 1.0 C2A C:HEM602 4.1 40.1 1.0 C3A C:HEM602 4.2 40.1 1.0 C3C C:HEM602 4.2 40.1 1.0 C2C C:HEM602 4.2 40.1 1.0 C2B C:HEM602 4.3 40.1 1.0 C3B C:HEM602 4.3 40.1 1.0

Iron binding site 3 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe401 b:55.9 occ:1.00 FE D:HEC401 0.0 55.9 1.0 SD D:MET225 2.0 57.8 1.0 NE2 D:HIS105 2.0 53.3 1.0 ND D:HEC401 2.1 55.9 1.0 NB D:HEC401 2.1 55.9 1.0 NA D:HEC401 2.1 55.9 1.0 NC D:HEC401 2.1 55.9 1.0 CD2 D:HIS105 2.9 53.3 1.0 CE1 D:HIS105 3.0 53.3 1.0 C1C D:HEC401 3.1 55.9 1.0 C4D D:HEC401 3.1 55.9 1.0 C4B D:HEC401 3.1 55.9 1.0 C1A D:HEC401 3.1 55.9 1.0 C1D D:HEC401 3.1 55.9 1.0 C4A D:HEC401 3.1 55.9 1.0 C1B D:HEC401 3.1 55.9 1.0 C4C D:HEC401 3.1 55.9 1.0 CG D:MET225 3.2 57.8 1.0 CHA D:HEC401 3.4 55.9 1.0 CHC D:HEC401 3.4 55.9 1.0 CHD D:HEC401 3.5 55.9 1.0 CE D:MET225 3.5 57.8 1.0 CHB D:HEC401 3.5 55.9 1.0 CB D:MET225 4.0 57.8 1.0 CG D:HIS105 4.1 53.3 1.0 ND1 D:HIS105 4.1 53.3 1.0 C3B D:HEC401 4.4 55.9 1.0 C2C D:HEC401 4.4 55.9 1.0 C3C D:HEC401 4.4 55.9 1.0 C3A D:HEC401 4.4 55.9 1.0 C2D D:HEC401 4.4 55.9 1.0 C3D D:HEC401 4.4 55.9 1.0 C2A D:HEC401 4.4 55.9 1.0 C2B D:HEC401 4.4 55.9 1.0

Iron binding site 4 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe301 b:0.7 occ:1.00 FE1 E:FES301 0.0 0.7 1.0 SG E:CYS178 2.2 0.7 1.0 SG E:CYS159 2.2 1.0 1.0 S2 E:FES301 2.2 0.7 1.0 S1 E:FES301 2.2 0.7 1.0 CB E:CYS159 2.7 1.0 1.0 CB E:CYS178 3.1 0.7 1.0 FE2 E:FES301 3.1 0.7 1.0 CB E:CYS164 3.9 0.5 1.0 CB E:HIS161 4.0 0.3 1.0 CA E:CYS159 4.0 1.0 1.0 OG E:SER183 4.1 0.1 1.0 N E:CYS164 4.2 0.5 1.0 C E:CYS159 4.3 1.0 1.0 O E:CYS159 4.4 1.0 1.0 CB E:SER183 4.4 0.1 1.0 N E:HIS161 4.5 0.3 1.0 CA E:CYS178 4.5 0.7 1.0 CA E:CYS164 4.5 0.5 1.0 N E:LEU162 4.6 0.4 1.0 ND1 E:HIS181 4.8 0.4 1.0 CA E:HIS161 4.8 0.3 1.0 O E:CYS164 4.8 0.5 1.0 OH E:TYR185 4.9 0.9 1.0 C E:CYS164 4.9 0.5 1.0 N E:THR160 4.9 0.0 1.0 N E:GLY163 4.9 0.8 1.0 CB E:CYS180 4.9 0.0 1.0 SG E:CYS164 4.9 0.5 1.0 ND1 E:HIS161 5.0 0.3 1.0 N E:CYS159 5.0 1.0 1.0 CG E:HIS161 5.0 0.3 1.0

Iron binding site 5 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe301 b:0.7 occ:1.00 FE2 E:FES301 0.0 0.7 1.0 ND1 E:HIS181 2.1 0.4 1.0 ND1 E:HIS161 2.2 0.3 1.0 S1 E:FES301 2.2 0.7 1.0 S2 E:FES301 2.2 0.7 1.0 CG E:HIS161 2.9 0.3 1.0 CB E:HIS161 2.9 0.3 1.0 CE1 E:HIS181 3.0 0.4 1.0 CG E:HIS181 3.0 0.4 1.0 FE1 E:FES301 3.1 0.7 1.0 CE1 E:HIS161 3.3 0.3 1.0 CB E:HIS181 3.4 0.4 1.0 NE2 E:HIS181 4.0 0.4 1.0 N E:LEU162 4.0 0.4 1.0 CD2 E:HIS181 4.0 0.4 1.0 SG E:CYS178 4.0 0.7 1.0 CD2 E:HIS161 4.1 0.3 1.0 N E:HIS181 4.1 0.4 1.0 CA E:HIS161 4.2 0.3 1.0 NE2 E:HIS161 4.2 0.3 1.0 CA E:HIS181 4.4 0.4 1.0 CB E:CYS180 4.4 0.0 1.0 CB E:LEU162 4.4 0.4 1.0 C E:HIS161 4.4 0.3 1.0 OG E:SER183 4.5 0.1 1.0 CG E:PRO195 4.6 0.9 1.0 CG E:LEU162 4.7 0.4 1.0 C E:CYS180 4.8 0.0 1.0 CA E:LEU162 4.8 0.4 1.0 CD1 E:LEU162 4.8 0.4 1.0 N E:HIS161 4.9 0.3 1.0 SG E:CYS159 4.9 1.0 1.0

Iron binding site 6 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ N:Fe601 b:44.0 occ:1.00 FE N:HEM601 0.0 44.0 1.0 ND N:HEM601 1.9 44.0 1.0 NA N:HEM601 2.0 44.0 1.0 NE2 N:HIS82 2.0 38.9 1.0 NE2 N:HIS183 2.0 38.5 1.0 NC N:HEM601 2.1 44.0 1.0 NB N:HEM601 2.1 44.0 1.0 CE1 N:HIS183 2.7 38.5 1.0 C4D N:HEM601 2.9 44.0 1.0 C1D N:HEM601 2.9 44.0 1.0 CE1 N:HIS82 2.9 38.9 1.0 C1A N:HEM601 2.9 44.0 1.0 C4A N:HEM601 3.0 44.0 1.0 C4C N:HEM601 3.0 44.0 1.0 CD2 N:HIS82 3.0 38.9 1.0 C1B N:HEM601 3.1 44.0 1.0 C4B N:HEM601 3.1 44.0 1.0 C1C N:HEM601 3.1 44.0 1.0 CD2 N:HIS183 3.2 38.5 1.0 CHA N:HEM601 3.3 44.0 1.0 CHD N:HEM601 3.4 44.0 1.0 CHB N:HEM601 3.5 44.0 1.0 CHC N:HEM601 3.5 44.0 1.0 ND1 N:HIS183 3.9 38.5 1.0 ND1 N:HIS82 4.0 38.9 1.0 C2A N:HEM601 4.1 44.0 1.0 C2D N:HEM601 4.1 44.0 1.0 CG N:HIS82 4.1 38.9 1.0 C3D N:HEM601 4.1 44.0 1.0 C3A N:HEM601 4.1 44.0 1.0 CG N:HIS183 4.2 38.5 1.0 C3C N:HEM601 4.2 44.0 1.0 C2C N:HEM601 4.3 44.0 1.0 C2B N:HEM601 4.3 44.0 1.0 C3B N:HEM601 4.3 44.0 1.0 CA N:GLY131 4.7 44.4 1.0

Iron binding site 7 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ N:Fe602 b:35.5 occ:1.00 FE N:HEM602 0.0 35.5 1.0 ND N:HEM602 1.9 35.5 1.0 NA N:HEM602 2.0 35.5 1.0 NE2 N:HIS96 2.0 45.0 1.0 NE2 N:HIS197 2.0 41.2 1.0 NC N:HEM602 2.1 35.5 1.0 NB N:HEM602 2.1 35.5 1.0 CD2 N:HIS96 2.8 45.0 1.0 C4D N:HEM602 2.9 35.5 1.0 C1D N:HEM602 2.9 35.5 1.0 CD2 N:HIS197 2.9 41.2 1.0 C1A N:HEM602 2.9 35.5 1.0 CE1 N:HIS197 3.0 41.2 1.0 C4C N:HEM602 3.0 35.5 1.0 C4A N:HEM602 3.0 35.5 1.0 C4B N:HEM602 3.1 35.5 1.0 C1B N:HEM602 3.1 35.5 1.0 C1C N:HEM602 3.1 35.5 1.0 CE1 N:HIS96 3.1 45.0 1.0 CHA N:HEM602 3.3 35.5 1.0 CHD N:HEM602 3.4 35.5 1.0 CHB N:HEM602 3.5 35.5 1.0 CHC N:HEM602 3.5 35.5 1.0 CG N:HIS197 4.0 41.2 1.0 CG N:HIS96 4.0 45.0 1.0 ND1 N:HIS197 4.0 41.2 1.0 C3D N:HEM602 4.1 35.5 1.0 C2D N:HEM602 4.1 35.5 1.0 ND1 N:HIS96 4.1 45.0 1.0 C2A N:HEM602 4.1 35.5 1.0 C3A N:HEM602 4.2 35.5 1.0 C3C N:HEM602 4.2 35.5 1.0 C2C N:HEM602 4.3 35.5 1.0 C2B N:HEM602 4.3 35.5 1.0 C3B N:HEM602 4.3 35.5 1.0

Iron binding site 8 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ O:Fe401 b:53.7 occ:1.00 FE O:HEC401 0.0 53.7 1.0 NE2 O:HIS105 2.0 50.6 1.0 SD O:MET225 2.0 54.5 1.0 NC O:HEC401 2.1 53.7 1.0 NA O:HEC401 2.1 53.7 1.0 ND O:HEC401 2.1 53.7 1.0 NB O:HEC401 2.1 53.7 1.0 CE1 O:HIS105 2.9 50.6 1.0 CD2 O:HIS105 2.9 50.6 1.0 C1C O:HEC401 3.1 53.7 1.0 C4A O:HEC401 3.1 53.7 1.0 C1B O:HEC401 3.1 53.7 1.0 C4C O:HEC401 3.1 53.7 1.0 C1A O:HEC401 3.1 53.7 1.0 C1D O:HEC401 3.1 53.7 1.0 C4D O:HEC401 3.1 53.7 1.0 C4B O:HEC401 3.1 53.7 1.0 CE O:MET225 3.4 54.5 1.0 CHD O:HEC401 3.4 53.7 1.0 CHC O:HEC401 3.4 53.7 1.0 CHA O:HEC401 3.5 53.7 1.0 CHB O:HEC401 3.5 53.7 1.0 CG O:MET225 3.5 54.5 1.0 ND1 O:HIS105 3.9 50.6 1.0 CG O:HIS105 4.0 50.6 1.0 CB O:MET225 4.3 54.5 1.0 C3C O:HEC401 4.4 53.7 1.0 C3A O:HEC401 4.4 53.7 1.0 C2C O:HEC401 4.4 53.7 1.0 C3B O:HEC401 4.4 53.7 1.0 C2A O:HEC401 4.4 53.7 1.0 C2B O:HEC401 4.4 53.7 1.0 C2D O:HEC401 4.4 53.7 1.0 C3D O:HEC401 4.4 53.7 1.0

Iron binding site 9 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe301 b:0.1 occ:1.00 FE1 P:FES301 0.0 0.1 1.0 SG P:CYS178 2.1 0.4 1.0 SG P:CYS159 2.1 0.6 1.0 S2 P:FES301 2.2 0.1 1.0 S1 P:FES301 2.2 0.1 1.0 CB P:CYS159 2.9 0.6 1.0 FE2 P:FES301 3.1 0.1 1.0 CB P:CYS178 3.1 0.4 1.0 OG P:SER183 3.8 0.8 1.0 CB P:HIS161 4.0 0.6 1.0 CA P:CYS159 4.1 0.6 1.0 CB P:SER183 4.2 0.8 1.0 CB P:CYS164 4.2 0.1 1.0 C P:CYS159 4.3 0.6 1.0 N P:CYS164 4.3 0.1 1.0 N P:HIS161 4.3 0.6 1.0 O P:CYS159 4.5 0.6 1.0 N P:LEU162 4.5 1.0 1.0 CA P:CYS178 4.6 0.4 1.0 OH P:TYR185 4.7 0.2 1.0 CA P:HIS161 4.7 0.6 1.0 N P:THR160 4.7 0.9 1.0 CA P:CYS164 4.8 0.1 1.0 ND1 P:HIS181 4.8 0.9 1.0 N P:GLY163 4.8 0.3 1.0 CB P:CYS180 4.8 0.6 1.0 O P:CYS164 4.9 0.1 1.0 ND1 P:HIS161 4.9 0.6 1.0 O P:CYS178 4.9 0.4 1.0 C P:CYS178 5.0 0.4 1.0 CG P:HIS161 5.0 0.6 1.0 SG P:CYS164 5.0 0.1 1.0

Iron binding site 10 out of 14 in the III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of III2-IV2 Mitochondrial Respiratory Supercomplex From S. Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe301 b:0.1 occ:1.00 FE2 P:FES301 0.0 0.1 1.0 ND1 P:HIS181 2.1 0.9 1.0 ND1 P:HIS161 2.1 0.6 1.0 S1 P:FES301 2.2 0.1 1.0 S2 P:FES301 2.2 0.1 1.0 CG P:HIS161 2.9 0.6 1.0 CE1 P:HIS181 2.9 0.9 1.0 CB P:HIS161 2.9 0.6 1.0 CG P:HIS181 3.0 0.9 1.0 FE1 P:FES301 3.1 0.1 1.0 CE1 P:HIS161 3.3 0.6 1.0 CB P:HIS181 3.5 0.9 1.0 N P:LEU162 3.8 1.0 1.0 NE2 P:HIS181 4.0 0.9 1.0 N P:HIS181 4.0 0.9 1.0 CD2 P:HIS181 4.0 0.9 1.0 CD2 P:HIS161 4.1 0.6 1.0 CA P:HIS161 4.2 0.6 1.0 CB P:LEU162 4.2 1.0 1.0 SG P:CYS178 4.2 0.4 1.0 CB P:CYS180 4.3 0.6 1.0 C P:HIS161 4.3 0.6 1.0 NE2 P:HIS161 4.3 0.6 1.0 CA P:HIS181 4.4 0.9 1.0 OG P:SER183 4.4 0.8 1.0 CG P:PRO195 4.5 0.6 1.0 CA P:LEU162 4.6 1.0 1.0 CG P:LEU162 4.6 1.0 1.0 C P:CYS180 4.7 0.6 1.0 N P:HIS161 4.8 0.6 1.0 SG P:CYS159 4.9 0.6 1.0 CD1 P:LEU162 5.0 1.0 1.0

A.M.Hartley, N.Lukoyanova, Y.Zhang, A.Cabrera-Orefice, S.Arnold, B.Meunier, N.Pinotsis, A.Marechal. Structure of Yeast Cytochrome C Oxidase in A Supercomplex with Cytochrome BC1. Nat. Struct. Mol. Biol. V. 26 78 2019.
ISSN: ESSN 1545-9985
PubMed: 30598554
DOI: 10.1038/S41594-018-0172-Z