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Atomistry » Iron » PDB 6ngf-6nlg » 6nh7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 6ngf-6nlg » 6nh7 » |
Iron in PDB 6nh7: Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-AmineProtein crystallography data
The structure of Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 6nh7
was solved by
G.Chreifi,
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6nh7:
The structure of Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine
(pdb code 6nh7). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine, PDB code: 6nh7: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 6nh7Go back to![]() ![]()
Iron binding site 1 out
of 2 in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Iron binding site 2 out of 2 in 6nh7Go back to![]() ![]()
Iron binding site 2 out
of 2 in the Structure of Human Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(3-(3-(Dimethylamino)Propyl)-2,5,6- Trifluorophenethyl)-4-Methylpyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
H.T.Do,
H.Li,
G.Chreifi,
T.L.Poulos,
R.B.Silverman.
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having A 2-Aminopyridine Scaffold. J. Med. Chem. V. 62 2690 2019.
Page generated: Wed Aug 7 03:23:15 2024
ISSN: ISSN 1520-4804 PubMed: 30802056 DOI: 10.1021/ACS.JMEDCHEM.8B02032 |
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