Iron in PDB 6qk7: Elongator Catalytic Subcomplex ELP123 Lobe

All present enzymatic activity of Elongator Catalytic Subcomplex ELP123 Lobe:
2.3.1.48;

The binding sites of Iron atom in the Elongator Catalytic Subcomplex ELP123 Lobe (pdb code 6qk7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Elongator Catalytic Subcomplex ELP123 Lobe, PDB code: 6qk7:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Elongator Catalytic Subcomplex ELP123 Lobe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Elongator Catalytic Subcomplex ELP123 Lobe within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe601 b:67.7 occ:1.00 FE1 C:SF4601 0.0 67.7 1.0 S2 C:SF4601 2.1 67.7 1.0 S4 C:SF4601 2.1 67.7 1.0 S3 C:SF4601 2.1 67.7 1.0 SG C:CYS108 2.3 58.1 1.0 FE4 C:SF4601 2.9 67.7 1.0 FE2 C:SF4601 3.0 67.7 1.0 FE3 C:SF4601 3.0 67.7 1.0 S1 C:SF4601 3.6 67.7 1.0 CB C:CYS108 3.9 58.1 1.0 CG C:GLN134 4.0 57.4 1.0 CE1 C:HIS110 4.0 61.8 1.0 SG C:CYS121 4.5 61.7 1.0 OG1 C:THR182 4.6 59.9 1.0 NE2 C:HIS110 4.7 61.8 1.0 CD C:GLN134 4.7 57.4 1.0 NE2 C:GLN134 4.8 57.4 1.0

Iron binding site 2 out of 4 in the Elongator Catalytic Subcomplex ELP123 Lobe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Elongator Catalytic Subcomplex ELP123 Lobe within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe601 b:67.7 occ:1.00 FE2 C:SF4601 0.0 67.7 1.0 S4 C:SF4601 2.1 67.7 1.0 S1 C:SF4601 2.1 67.7 1.0 S3 C:SF4601 2.1 67.7 1.0 FE1 C:SF4601 3.0 67.7 1.0 FE3 C:SF4601 3.0 67.7 1.0 FE4 C:SF4601 3.1 67.7 1.0 S2 C:SF4601 3.7 67.7 1.0 NH1 C:ARG269 3.8 60.1 1.0 C5' C:5AD602 4.6 20.0 1.0 CZ C:ARG269 4.7 60.1 1.0 NH2 C:ARG269 4.7 60.1 1.0 SG C:CYS108 4.9 58.1 1.0

Iron binding site 3 out of 4 in the Elongator Catalytic Subcomplex ELP123 Lobe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Elongator Catalytic Subcomplex ELP123 Lobe within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe601 b:67.7 occ:1.00 FE3 C:SF4601 0.0 67.7 1.0 S2 C:SF4601 2.1 67.7 1.0 S4 C:SF4601 2.1 67.7 1.0 S1 C:SF4601 2.1 67.7 1.0 SG C:CYS118 2.3 65.3 1.0 CB C:CYS118 3.0 65.3 1.0 FE4 C:SF4601 3.0 67.7 1.0 FE2 C:SF4601 3.0 67.7 1.0 FE1 C:SF4601 3.0 67.7 1.0 NH1 C:ARG269 3.6 60.1 1.0 S3 C:SF4601 3.7 67.7 1.0 CE1 C:HIS110 3.9 61.8 1.0 NE2 C:HIS110 3.9 61.8 1.0 N C:CYS118 4.0 65.3 1.0 CA C:CYS118 4.1 65.3 1.0 CB C:CYS121 4.6 61.7 1.0 CZ C:ARG269 4.7 60.1 1.0 OH C:TYR120 4.8 60.3 1.0 SG C:CYS108 4.9 58.1 1.0 SG C:CYS121 5.0 61.7 1.0

Iron binding site 4 out of 4 in the Elongator Catalytic Subcomplex ELP123 Lobe


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Elongator Catalytic Subcomplex ELP123 Lobe within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe601 b:67.7 occ:1.00 FE4 C:SF4601 0.0 67.7 1.0 S3 C:SF4601 2.1 67.7 1.0 S2 C:SF4601 2.1 67.7 1.0 S1 C:SF4601 2.1 67.7 1.0 SG C:CYS121 2.3 61.7 1.0 CB C:CYS121 2.8 61.7 1.0 FE1 C:SF4601 2.9 67.7 1.0 FE3 C:SF4601 3.0 67.7 1.0 FE2 C:SF4601 3.1 67.7 1.0 S4 C:SF4601 3.7 67.7 1.0 CA C:CYS121 4.1 61.7 1.0 NE2 C:GLN134 4.3 57.4 1.0 CB C:SER135 4.3 58.6 1.0 CG C:GLN134 4.3 57.4 1.0 CB C:CYS118 4.5 65.3 1.0 CD C:GLN134 4.8 57.4 1.0 SG C:CYS118 4.9 65.3 1.0 N C:CYS121 4.9 61.7 1.0 C8 C:5AD602 4.9 20.0 1.0

M.I.Dauden, M.Jaciuk, F.Weis, T.Y.Lin, C.Kleindienst, N.E.H.Abbassi, H.Khatter, R.Krutyholowa, K.D.Breunig, J.Kosinski, C.W.Muller, S.Glatt. Molecular Basis of Trna Recognition By the Elongator Complex. Sci Adv V. 5 W2326 2019.
ISSN: ESSN 2375-2548
PubMed: 31309145
DOI: 10.1126/SCIADV.AAW2326