Atomistry » Iron » PDB 6r2q-6rr1 » 6rfs
Atomistry »
  Iron »
    PDB 6r2q-6rr1 »
      6rfs »

Iron in PDB 6rfs: Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4

Enzymatic activity of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4

All present enzymatic activity of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4:
1.6.5.3; 1.6.99.3; 7.1.1.2;

Other elements in 6rfs:

The structure of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Iron Binding Sites:

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 (pdb code 6rfs). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4, PDB code: 6rfs:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 1 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe801

b:0.3
occ:1.00
 FE1 A:SF4801 0.0 0.3 1.0
S2 A:SF4801 2.2 0.3 1.0
S3 A:SF4801 2.3 0.3 1.0
S4 A:SF4801 2.3 0.3 1.0
SG A:CYS142 2.3 0.8 1.0
CB A:CYS142 2.6 0.8 1.0
FE4 A:SF4801 2.6 0.3 1.0
FE3 A:SF4801 2.6 0.3 1.0
FE2 A:SF4801 2.7 0.3 1.0
O A:GLN138 3.7 0.4 1.0
S1 A:SF4801 3.9 0.3 1.0
OE1 A:GLN145 4.0 0.8 1.0
CA A:CYS142 4.1 0.8 1.0
CB A:GLN145 4.3 0.8 1.0
SG A:CYS136 4.3 0.6 1.0
CD A:GLN145 4.7 0.8 1.0
NE2 A:HIS129 4.8 95.9 1.0
SG A:CYS133 4.8 0.3 1.0
C A:GLN138 4.8 0.4 1.0
CB A:CYS136 4.9 0.6 1.0
N A:CYS142 4.9 0.8 1.0
C A:CYS142 5.0 0.8 1.0

Iron binding site 2 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 2 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe801

b:0.3
occ:1.00
 FE2 A:SF4801 0.0 0.3 1.0
S1 A:SF4801 2.2 0.3 1.0
S4 A:SF4801 2.3 0.3 1.0
S3 A:SF4801 2.3 0.3 1.0
SG A:CYS133 2.3 0.3 1.0
FE3 A:SF4801 2.6 0.3 1.0
FE4 A:SF4801 2.6 0.3 1.0
FE1 A:SF4801 2.7 0.3 1.0
CA A:CYS133 3.0 0.3 1.0
CB A:CYS133 3.0 0.3 1.0
N A:CYS133 3.4 0.3 1.0
S2 A:SF4801 3.8 0.3 1.0
C A:ASP132 4.2 0.1 1.0
C A:CYS133 4.3 0.3 1.0
NE2 A:HIS129 4.3 95.9 1.0
CB A:CYS136 4.4 0.6 1.0
OE1 A:GLN145 4.5 0.8 1.0
O A:CYS133 4.5 0.3 1.0
O A:ASP132 4.6 0.1 1.0
CE C:MET378 4.8 1.0 1.0
SG A:CYS136 4.8 0.6 1.0
CG2 C:ILE382 4.8 0.3 1.0
SG A:CYS142 4.8 0.8 1.0
CD A:GLN145 4.9 0.8 1.0

Iron binding site 3 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 3 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe801

b:0.3
occ:1.00
 FE3 A:SF4801 0.0 0.3 1.0
NE2 A:HIS129 2.1 95.9 1.0
S4 A:SF4801 2.2 0.3 1.0
S2 A:SF4801 2.3 0.3 1.0
S1 A:SF4801 2.3 0.3 1.0
FE4 A:SF4801 2.6 0.3 1.0
FE2 A:SF4801 2.6 0.3 1.0
FE1 A:SF4801 2.6 0.3 1.0
CE1 A:HIS129 3.0 95.9 1.0
CD2 A:HIS129 3.1 95.9 1.0
S3 A:SF4801 3.8 0.3 1.0
SG A:CYS142 3.9 0.8 1.0
ND1 A:HIS129 4.1 95.9 1.0
CG A:HIS129 4.2 95.9 1.0
SG A:CYS133 4.3 0.3 1.0
CD2 A:LEU144 4.7 0.3 1.0
SG A:CYS136 4.7 0.6 1.0
CE C:MET378 4.8 1.0 1.0

Iron binding site 4 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 4 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe801

b:0.3
occ:1.00
 FE4 A:SF4801 0.0 0.3 1.0
S3 A:SF4801 2.2 0.3 1.0
S1 A:SF4801 2.3 0.3 1.0
S2 A:SF4801 2.3 0.3 1.0
SG A:CYS136 2.3 0.6 1.0
CB A:CYS136 2.6 0.6 1.0
FE3 A:SF4801 2.6 0.3 1.0
FE1 A:SF4801 2.6 0.3 1.0
FE2 A:SF4801 2.6 0.3 1.0
S4 A:SF4801 3.8 0.3 1.0
CD A:ARG182 4.0 0.7 1.0
CA A:CYS136 4.1 0.6 1.0
NE2 A:HIS129 4.1 95.9 1.0
CA A:CYS133 4.4 0.3 1.0
O A:ASP132 4.5 0.1 1.0
O A:GLN138 4.5 0.4 1.0
N A:CYS133 4.5 0.3 1.0
NE A:ARG182 4.6 0.7 1.0
C A:ASP132 4.6 0.1 1.0
SG A:CYS142 4.6 0.8 1.0
CE1 A:HIS129 4.6 95.9 1.0
N A:GLY236 4.7 0.8 1.0
C A:CYS136 4.7 0.6 1.0
N A:CYS136 4.8 0.6 1.0
SG A:CYS133 4.8 0.3 1.0
CB A:CYS142 4.9 0.8 1.0

Iron binding site 5 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 5 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe802

b:0.1
occ:1.00
 FE1 A:SF4802 0.0 0.1 1.0
S2 A:SF4802 2.2 0.1 1.0
S3 A:SF4802 2.3 0.1 1.0
S4 A:SF4802 2.3 0.1 1.0
SG A:CYS186 2.3 0.4 1.0
FE4 A:SF4802 2.6 0.1 1.0
FE3 A:SF4802 2.7 0.1 1.0
FE2 A:SF4802 2.7 0.1 1.0
CB A:CYS186 3.5 0.4 1.0
N A:CYS186 3.5 0.4 1.0
SG A:CYS233 3.7 0.8 1.0
S1 A:SF4802 3.8 0.1 1.0
CA A:CYS186 3.9 0.4 1.0
CD A:PRO234 4.1 0.7 1.0
N A:THR187 4.3 0.2 1.0
SG A:CYS183 4.3 0.7 1.0
C A:CYS186 4.3 0.4 1.0
CB A:CYS233 4.4 0.8 1.0
CA A:CYS233 4.5 0.8 1.0
C A:HIS185 4.6 0.4 1.0
N A:ARG188 4.7 0.7 1.0
N A:HIS185 4.7 0.4 1.0
CG1 A:ILE184 4.8 0.4 1.0
N A:CYS189 4.9 0.3 1.0
CA A:HIS185 4.9 0.4 1.0
SG A:CYS189 4.9 0.3 1.0
N A:ILE184 4.9 0.4 1.0
O A:CYS186 5.0 0.4 1.0

Iron binding site 6 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 6 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe802

b:0.1
occ:1.00
 FE2 A:SF4802 0.0 0.1 1.0
S1 A:SF4802 2.3 0.1 1.0
S3 A:SF4802 2.3 0.1 1.0
S4 A:SF4802 2.3 0.1 1.0
SG A:CYS183 2.3 0.7 1.0
FE3 A:SF4802 2.7 0.1 1.0
FE1 A:SF4802 2.7 0.1 1.0
FE4 A:SF4802 2.7 0.1 1.0
CB A:CYS183 3.6 0.7 1.0
S2 A:SF4802 3.8 0.1 1.0
N A:HIS185 4.0 0.4 1.0
CA A:HIS185 4.1 0.4 1.0
CG1 A:ILE213 4.1 0.9 1.0
N A:CYS186 4.2 0.4 1.0
SG A:CYS189 4.2 0.3 1.0
CA A:CYS183 4.4 0.7 1.0
N A:ILE184 4.5 0.4 1.0
SG A:CYS233 4.7 0.8 1.0
C A:HIS185 4.7 0.4 1.0
CB A:ILE213 4.7 0.9 1.0
SG A:CYS186 4.7 0.4 1.0
CE A:MET180 4.8 0.5 1.0
CG2 A:ILE213 4.9 0.9 1.0
C A:CYS183 4.9 0.7 1.0

Iron binding site 7 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 7 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe802

b:0.1
occ:1.00
 FE3 A:SF4802 0.0 0.1 1.0
S4 A:SF4802 2.2 0.1 1.0
S2 A:SF4802 2.3 0.1 1.0
SG A:CYS189 2.3 0.3 1.0
S1 A:SF4802 2.3 0.1 1.0
FE1 A:SF4802 2.7 0.1 1.0
FE2 A:SF4802 2.7 0.1 1.0
CB A:CYS189 2.7 0.3 1.0
FE4 A:SF4802 2.7 0.1 1.0
N A:CYS189 3.2 0.3 1.0
CA A:CYS189 3.5 0.3 1.0
S3 A:SF4802 3.8 0.1 1.0
SG A:CYS186 4.1 0.4 1.0
N A:ARG188 4.2 0.7 1.0
N A:THR187 4.3 0.2 1.0
C A:ARG188 4.4 0.7 1.0
N A:VAL190 4.5 0.8 1.0
C A:CYS189 4.6 0.3 1.0
C A:THR187 4.6 0.2 1.0
SG A:CYS233 4.7 0.8 1.0
CB A:CYS233 4.7 0.8 1.0
CA A:ARG188 4.8 0.7 1.0
CA A:THR187 4.8 0.2 1.0
N A:CYS186 4.9 0.4 1.0
CG2 A:ILE213 4.9 0.9 1.0
SG A:CYS183 5.0 0.7 1.0

Iron binding site 8 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 8 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe802

b:0.1
occ:1.00
 FE4 A:SF4802 0.0 0.1 1.0
S3 A:SF4802 2.2 0.1 1.0
S1 A:SF4802 2.3 0.1 1.0
S2 A:SF4802 2.3 0.1 1.0
SG A:CYS233 2.3 0.8 1.0
FE1 A:SF4802 2.6 0.1 1.0
FE2 A:SF4802 2.7 0.1 1.0
FE3 A:SF4802 2.7 0.1 1.0
CB A:CYS233 3.0 0.8 1.0
S4 A:SF4802 3.8 0.1 1.0
CA A:CYS233 4.0 0.8 1.0
CB A:ALA237 4.0 0.4 1.0
CD1 A:LEU238 4.2 0.7 1.0
CG A:LEU238 4.4 0.7 1.0
SG A:CYS183 4.4 0.7 1.0
CB A:CYS189 4.5 0.3 1.0
SG A:CYS189 4.6 0.3 1.0
SG A:CYS186 4.7 0.4 1.0
N A:LEU238 4.8 0.7 1.0
CB A:CYS183 4.9 0.7 1.0
CB A:LEU238 4.9 0.7 1.0
C A:CYS233 4.9 0.8 1.0

Iron binding site 9 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 9 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe803

b:0.9
occ:1.00
 FE1 A:FES803 0.0 0.9 1.0
S2 A:FES803 2.2 0.9 1.0
S1 A:FES803 2.2 0.9 1.0
SG A:CYS69 2.3 0.8 1.0
SG A:CYS80 2.3 0.4 1.0
N A:CYS80 2.8 0.4 1.0
CB A:CYS80 2.9 0.4 1.0
FE2 A:FES803 3.0 0.9 1.0
CA A:CYS80 3.3 0.4 1.0
C A:GLY78 3.5 0.5 1.0
N A:ASN79 3.5 0.3 1.0
O A:ALA77 3.6 0.9 1.0
N A:ARG81 3.6 0.8 1.0
CA A:GLY78 3.7 0.5 1.0
CB A:CYS69 3.8 0.8 1.0
C A:ASN79 3.9 0.3 1.0
C A:CYS80 3.9 0.4 1.0
O A:GLY78 4.0 0.5 1.0
SG A:CYS97 4.1 0.1 1.0
N A:CYS69 4.2 0.8 1.0
CA A:CYS69 4.3 0.8 1.0
CA A:ASN79 4.3 0.3 1.0
C A:CYS69 4.3 0.8 1.0
N A:TYR70 4.5 0.8 1.0
C A:ALA77 4.5 0.9 1.0
N A:GLY78 4.6 0.5 1.0
N A:MET82 4.8 0.1 1.0
O A:CYS69 4.8 0.8 1.0
CA A:ARG81 4.8 0.8 1.0
CB A:CYS97 4.9 0.1 1.0
SG A:CYS83 4.9 0.0 1.0
O A:ASN79 4.9 0.3 1.0
O A:CYS80 5.0 0.4 1.0

Iron binding site 10 out of 28 in 6rfs

Go back to Iron Binding Sites List in 6rfs
Iron binding site 10 out of 28 in the Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Cryo-Em Structure of A Respiratory Complex I Mutant Lacking NDUFS4 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe803

b:0.9
occ:1.00
 FE2 A:FES803 0.0 0.9 1.0
SG A:CYS83 2.2 0.0 1.0
S2 A:FES803 2.2 0.9 1.0
S1 A:FES803 2.2 0.9 1.0
SG A:CYS97 2.3 0.1 1.0
CB A:CYS97 2.7 0.1 1.0
FE1 A:FES803 3.0 0.9 1.0
CB A:CYS83 3.5 0.0 1.0
N A:CYS97 3.7 0.1 1.0
SG A:CYS80 3.7 0.4 1.0
CA A:CYS97 3.8 0.1 1.0
N A:CYS83 4.1 0.0 1.0
CB A:ALA95 4.1 0.2 1.0
CA A:CYS83 4.4 0.0 1.0
N A:SER96 4.7 0.6 1.0
CA A:GLY78 4.8 0.5 1.0
C A:CYS97 4.8 0.1 1.0
C A:SER96 4.9 0.6 1.0
CB A:TYR70 4.9 0.8 1.0
CA A:ALA95 4.9 0.2 1.0
SG A:CYS69 5.0 0.8 1.0

Reference:

K.Parey, O.Haapanen, V.Sharma, H.Kofeler, T.Zullig, S.Prinz, K.Siegmund, I.Wittig, D.J.Mills, J.Vonck, W.Kuhlbrandt, V.Zickermann. High-Resolution Cryo-Em Structures of Respiratory Complex I: Mechanism, Assembly, and Disease. Sci Adv V. 5 X9484 2019.
ISSN: ESSN 2375-2548
PubMed: 31844670
DOI: 10.1126/SCIADV.AAX9484
Page generated: Wed Aug 7 08:43:22 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy