Atomistry » Iron » PDB 6sor-6tjv » 6t0g
Atomistry »
  Iron »
    PDB 6sor-6tjv »
      6t0g »

Iron in PDB 6t0g: Crystal Structure of CYP124 in Complex with Vitamin D3

Enzymatic activity of Crystal Structure of CYP124 in Complex with Vitamin D3

All present enzymatic activity of Crystal Structure of CYP124 in Complex with Vitamin D3:
1.14.15.14; 1.14.15.28;

Protein crystallography data

The structure of Crystal Structure of CYP124 in Complex with Vitamin D3, PDB code: 6t0g was solved by S.Bukhdruker, E.Marin, T.Varaksa, A.Gilep, N.Strushkevich, V.Borshchevskiy, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.75 / 1.30
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 51.540, 75.110, 56.590, 90.00, 106.84, 90.00
R / Rfree (%) 16.3 / 19

Other elements in 6t0g:

The structure of Crystal Structure of CYP124 in Complex with Vitamin D3 also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Crystal Structure of CYP124 in Complex with Vitamin D3 (pdb code 6t0g). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of CYP124 in Complex with Vitamin D3, PDB code: 6t0g:

Iron binding site 1 out of 1 in 6t0g

Go back to Iron Binding Sites List in 6t0g
Iron binding site 1 out of 1 in the Crystal Structure of CYP124 in Complex with Vitamin D3


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of CYP124 in Complex with Vitamin D3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe501

b:8.4
occ:1.00
FE A:HEM501 0.0 8.4 1.0
ND A:HEM501 2.0 8.8 1.0
NB A:HEM501 2.0 7.5 1.0
NA A:HEM501 2.1 8.9 1.0
NC A:HEM501 2.1 7.3 1.0
SG A:CYS379 2.4 8.3 1.0
C4B A:HEM501 3.1 8.9 1.0
C4D A:HEM501 3.1 8.8 1.0
C1B A:HEM501 3.1 7.5 1.0
C1D A:HEM501 3.1 8.1 1.0
C1A A:HEM501 3.1 8.5 1.0
C4A A:HEM501 3.1 8.4 1.0
C4C A:HEM501 3.1 8.0 1.0
C1C A:HEM501 3.1 7.9 1.0
CB A:CYS379 3.4 8.5 1.0
CHC A:HEM501 3.4 8.7 1.0
CHB A:HEM501 3.5 7.6 1.0
CHA A:HEM501 3.5 8.8 1.0
CHD A:HEM501 3.5 8.4 1.0
CA A:CYS379 4.0 8.9 1.0
C27 A:VD3502 4.0 13.9 1.0
C2B A:HEM501 4.3 8.2 1.0
C3A A:HEM501 4.3 7.7 1.0
C2A A:HEM501 4.3 7.7 1.0
C3C A:HEM501 4.3 8.6 1.0
C3B A:HEM501 4.3 9.0 1.0
C2C A:HEM501 4.3 8.8 1.0
C2D A:HEM501 4.3 8.9 1.0
C3D A:HEM501 4.4 8.9 1.0
N A:GLY381 4.5 8.1 1.0
C A:CYS379 4.6 8.4 1.0
N A:LEU380 4.6 8.4 1.0
CA A:GLY381 4.9 9.0 1.0
CB A:ALA267 4.9 9.6 1.0

Reference:

T.Varaksa, S.Bukhdruker, I.Grabovec, E.Marin, A.Kavaleuski, A.Gusach, K.Kovalev, I.Maslov, A.Luginina, D.Zabelskiy, R.Astashkin, M.Shevtsov, S.Smolskaya, A.Kavaleuskaya, P.Shabunya, A.Baranovsky, V.Dolgopalets, Y.Charnou, A.Savachka, R.Litvinovskaya, E.Shevchenko, A.Rogachev, A.Mishin, V.Gordeliy, A.Gabrielian, D.E.Hurt, B.Nikonenko, K.Majorov, A.Apt, A.Rosenthal, A.Gilep, V.Borshchevskiy, N.Strushkevich. Metabolic Fate of Human Immunoactive Oxysterols in Mycobacterium Tuberculosis. To Be Published.
Page generated: Wed Aug 7 10:36:15 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy