Iron in PDB 6x8x: Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1

The structure of Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1, PDB code: 6x8x was solved by F.A.Tezcan, A.Kakkis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.84 / 2.51
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	82.172, 82.172, 48.072, 90.00, 90.00, 120.00
R / Rfree (%)	28.5 / 34.2

The structure of Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1 also contains other interesting chemical elements:

Copper	(Cu)	1 atom
Calcium	(Ca)	5 atoms

The binding sites of Iron atom in the Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1 (pdb code 6x8x). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1, PDB code: 6x8x:

Iron binding site 1 out of 1 in the Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cu-Bound Structure of An Engineered Metal-Dependent Protein Trimer, TRICYT1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:37.7 occ:1.00 FE A:HEC201 0.0 37.7 1.0 NC A:HEC201 2.0 41.4 1.0 NA A:HEC201 2.0 45.4 1.0 NB A:HEC201 2.1 46.6 1.0 ND A:HEC201 2.2 47.8 1.0 NE2 A:HIS102 2.4 44.1 1.0 SD A:MET7 2.4 38.5 1.0 C1C A:HEC201 3.0 47.0 1.0 C4C A:HEC201 3.0 47.8 1.0 C4A A:HEC201 3.0 50.5 1.0 C4B A:HEC201 3.1 41.8 1.0 C1A A:HEC201 3.1 51.2 1.0 C1B A:HEC201 3.1 41.5 1.0 C1D A:HEC201 3.1 44.0 1.0 C4D A:HEC201 3.2 47.6 1.0 CD2 A:HIS102 3.2 52.7 1.0 CHC A:HEC201 3.4 42.0 1.0 CE1 A:HIS102 3.4 48.6 1.0 CHB A:HEC201 3.4 46.6 1.0 CHD A:HEC201 3.5 41.4 1.0 CE A:MET7 3.5 45.0 1.0 CHA A:HEC201 3.5 53.3 1.0 CG A:MET7 3.6 47.3 1.0 C2C A:HEC201 4.2 41.5 1.0 C3C A:HEC201 4.2 49.3 1.0 CB A:MET7 4.2 45.9 1.0 C3A A:HEC201 4.3 50.6 1.0 C2A A:HEC201 4.3 45.5 1.0 C3B A:HEC201 4.3 45.8 1.0 C2B A:HEC201 4.3 46.5 1.0 C2D A:HEC201 4.4 53.5 1.0 CG A:HIS102 4.4 50.5 1.0 C3D A:HEC201 4.4 54.3 1.0 ND1 A:HIS102 4.4 48.7 1.0 CA A:MET7 5.0 45.0 1.0

F.A.Tezcan, A.Kakkis, D.Gagnon, J.Esselborn, R.D.Britt. Metal-Templated Design of Chemically Switchable Protein Assemblies with High-Affinity Coordination Sites. Angew.Chem.Int.Ed.Engl. 2020.
ISSN: ESSN 1521-3773
PubMed: 32830423
DOI: 10.1002/ANIE.202009226