Iron in PDB 7du2: Rna Polymerase III Ec Complex in Post-Translocation State

Enzymatic activity of Rna Polymerase III Ec Complex in Post-Translocation State

All present enzymatic activity of Rna Polymerase III Ec Complex in Post-Translocation State:
2.7.7.6;

Other elements in 7du2:

The structure of Rna Polymerase III Ec Complex in Post-Translocation State also contains other interesting chemical elements:

Zinc (Zn) 6 atoms
Magnesium (Mg) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Rna Polymerase III Ec Complex in Post-Translocation State (pdb code 7du2). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Rna Polymerase III Ec Complex in Post-Translocation State, PDB code: 7du2:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 7du2

Go back to Iron Binding Sites List in 7du2
Iron binding site 1 out of 4 in the Rna Polymerase III Ec Complex in Post-Translocation State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Rna Polymerase III Ec Complex in Post-Translocation State within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:119.5
occ:1.00
 FE1 P:SF4401 0.0 119.5 1.0
S2 P:SF4401 2.1 119.5 1.0
S3 P:SF4401 2.1 119.5 1.0
S4 P:SF4401 2.1 119.5 1.0
SG P:CYS287 2.6 121.3 1.0
FE4 P:SF4401 3.0 119.5 1.0
FE3 P:SF4401 3.0 119.5 1.0
FE2 P:SF4401 3.0 119.5 1.0
CB P:CYS287 3.1 121.3 1.0
S1 P:SF4401 3.7 119.5 1.0
CB O:ASN445 3.9 118.3 1.0
CA P:CYS287 4.0 121.3 1.0
OD1 O:ASN445 4.1 118.3 1.0
CG O:ASN445 4.3 118.3 1.0
SG P:CYS290 4.7 126.7 1.0
CG P:MET310 4.8 121.4 1.0
O P:CYS287 4.9 121.3 1.0
CB P:PRO304 5.0 112.1 1.0
SD P:MET310 5.0 121.4 1.0
N P:CYS287 5.0 121.3 1.0

Iron binding site 2 out of 4 in 7du2

Go back to Iron Binding Sites List in 7du2
Iron binding site 2 out of 4 in the Rna Polymerase III Ec Complex in Post-Translocation State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Rna Polymerase III Ec Complex in Post-Translocation State within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:119.5
occ:1.00
 FE2 P:SF4401 0.0 119.5 1.0
S3 P:SF4401 2.1 119.5 1.0
S4 P:SF4401 2.1 119.5 1.0
S1 P:SF4401 2.1 119.5 1.0
CD2 P:PHE293 2.6 122.0 1.0
CB P:CYS307 3.0 120.8 1.0
FE3 P:SF4401 3.0 119.5 1.0
FE1 P:SF4401 3.0 119.5 1.0
FE4 P:SF4401 3.0 119.5 1.0
SG P:CYS307 3.2 120.8 1.0
CE2 P:PHE293 3.3 122.0 1.0
CG P:PHE293 3.7 122.0 1.0
S2 P:SF4401 3.7 119.5 1.0
CB P:PHE293 4.0 122.0 1.0
CD2 P:TYR309 4.4 119.9 1.0
CA P:CYS307 4.5 120.8 1.0
CB P:TYR309 4.6 119.9 1.0
CZ P:PHE293 4.7 122.0 1.0
O P:PHE293 4.7 122.0 1.0
CA P:PRO304 4.8 112.1 1.0
SG P:CYS290 4.9 126.7 1.0
CB P:PRO304 4.9 112.1 1.0
CD1 P:PHE293 4.9 122.0 1.0

Iron binding site 3 out of 4 in 7du2

Go back to Iron Binding Sites List in 7du2
Iron binding site 3 out of 4 in the Rna Polymerase III Ec Complex in Post-Translocation State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Rna Polymerase III Ec Complex in Post-Translocation State within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:119.5
occ:1.00
 FE3 P:SF4401 0.0 119.5 1.0
S2 P:SF4401 2.1 119.5 1.0
S1 P:SF4401 2.1 119.5 1.0
S4 P:SF4401 2.1 119.5 1.0
O P:PHE293 2.4 122.0 1.0
FE2 P:SF4401 3.0 119.5 1.0
FE1 P:SF4401 3.0 119.5 1.0
FE4 P:SF4401 3.0 119.5 1.0
C P:PHE293 3.0 122.0 1.0
CB P:PHE293 3.3 122.0 1.0
CA P:PHE293 3.7 122.0 1.0
S3 P:SF4401 3.7 119.5 1.0
N P:ASP294 3.9 118.9 1.0
SG P:CYS287 3.9 121.3 1.0
SG P:CYS290 3.9 126.7 1.0
CD2 P:PHE293 4.0 122.0 1.0
CG P:PHE293 4.1 122.0 1.0
CA P:ASP294 4.2 118.9 1.0
OD1 O:ASN445 4.3 118.3 1.0
SG P:CYS296 4.5 104.7 1.0
C P:ASP294 4.8 118.9 1.0
O P:ASP294 4.9 118.9 1.0
NZ O:LYS441 4.9 114.0 1.0
N P:PHE293 5.0 122.0 1.0
CG O:ASN445 5.0 118.3 1.0

Iron binding site 4 out of 4 in 7du2

Go back to Iron Binding Sites List in 7du2
Iron binding site 4 out of 4 in the Rna Polymerase III Ec Complex in Post-Translocation State


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Rna Polymerase III Ec Complex in Post-Translocation State within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Fe401

b:119.5
occ:1.00
 FE4 P:SF4401 0.0 119.5 1.0
S1 P:SF4401 2.1 119.5 1.0
S2 P:SF4401 2.1 119.5 1.0
S3 P:SF4401 2.1 119.5 1.0
CB P:PRO304 2.5 112.1 1.0
FE1 P:SF4401 3.0 119.5 1.0
FE2 P:SF4401 3.0 119.5 1.0
FE3 P:SF4401 3.0 119.5 1.0
CG O:ASN445 3.2 118.3 1.0
CA P:PRO304 3.2 112.1 1.0
OD1 O:ASN445 3.3 118.3 1.0
ND2 O:ASN445 3.4 118.3 1.0
CG P:PRO304 3.4 112.1 1.0
CB O:ASN445 3.7 118.3 1.0
S4 P:SF4401 3.7 119.5 1.0
N P:PRO304 3.8 112.1 1.0
CD P:PRO304 3.8 112.1 1.0
SG P:CYS296 4.2 104.7 1.0
O P:ILE302 4.5 111.4 1.0
C P:PRO304 4.5 112.1 1.0
O P:PHE293 4.5 122.0 1.0
CB P:CYS307 4.7 120.8 1.0
C P:SER303 4.7 113.1 1.0
CB P:CYS296 4.7 104.7 1.0
O P:PRO304 4.8 112.1 1.0
CA O:ASN445 5.0 118.3 1.0

Reference:

L.Li, Z.Yu, D.Zhao, Y.Ren, H.Hou, Y.Xu. Structure of Human Rna Polymerase III Elongation Complex. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 33674783
DOI: 10.1038/S41422-021-00472-2
Page generated: Sat Apr 3 15:54:30 2021

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