Iron in PDB 7e5z: Dehydrogenase Holoenzyme

All present enzymatic activity of Dehydrogenase Holoenzyme:
1.17.1.9; 1.2.1.2;

The structure of Dehydrogenase Holoenzyme also contains other interesting chemical elements:

Tungsten

(W)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20;

Binding sites:

The binding sites of Iron atom in the Dehydrogenase Holoenzyme (pdb code 7e5z). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 20 binding sites of Iron where determined in the Dehydrogenase Holoenzyme, PDB code: 7e5z:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1003 b:86.7 occ:1.00 FE1 A:FES1003 0.0 86.7 1.0 S2 A:FES1003 2.2 86.7 1.0 S1 A:FES1003 2.2 86.7 1.0 SG A:CYS102 2.3 78.3 1.0 SG A:CYS115 2.3 81.5 1.0 H A:ARG116 2.8 81.0 1.0 FE2 A:FES1003 3.0 86.7 1.0 H A:CYS115 3.4 81.5 1.0 SG A:CYS118 3.4 82.9 1.0 H A:ALA117 3.4 81.2 1.0 HA2 A:GLY113 3.5 83.8 1.0 N A:ARG116 3.5 81.0 1.0 H A:ASN114 3.8 83.1 1.0 CB A:CYS115 3.8 81.5 1.0 CB A:CYS102 3.9 78.3 1.0 N A:CYS115 3.9 81.5 1.0 O A:HIS100 3.9 80.7 1.0 H A:CYS102 3.9 78.3 1.0 HA A:ARG116 4.0 81.0 1.0 H A:CYS118 4.1 82.9 1.0 CA A:CYS115 4.2 81.5 1.0 N A:ALA117 4.2 81.2 1.0 CA A:ARG116 4.3 81.0 1.0 C A:CYS115 4.3 81.5 1.0 N A:ASN114 4.3 83.1 1.0 CA A:GLY113 4.3 83.8 1.0 H A:GLY113 4.4 83.8 1.0 OD1 A:ASN114 4.5 83.1 1.0 SG A:CYS132 4.5 85.0 1.0 N A:CYS102 4.7 78.3 1.0 CA A:CYS102 4.7 78.3 1.0 C A:GLY113 4.7 83.8 1.0 HA A:HIS100 4.8 80.7 1.0 HB3 A:ALA117 4.8 81.2 1.0 N A:CYS118 4.8 82.9 1.0 C A:ASN114 4.8 83.1 1.0 C A:ARG116 4.8 81.0 1.0 HD2 A:ARG116 4.8 81.0 1.0 HB2 A:HIS103 4.8 80.0 1.0 C A:CYS102 4.8 78.3 1.0 N A:GLY113 4.8 83.8 1.0 CB A:CYS118 4.9 82.9 1.0 C A:HIS100 4.9 80.7 1.0 HB3 A:HIS103 5.0 80.0 1.0

Iron binding site 2 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1003 b:86.7 occ:1.00 FE2 A:FES1003 0.0 86.7 1.0 S2 A:FES1003 2.2 86.7 1.0 S1 A:FES1003 2.2 86.7 1.0 SG A:CYS132 2.3 85.0 1.0 SG A:CYS118 2.3 82.9 1.0 CB A:CYS132 2.6 85.0 1.0 FE1 A:FES1003 3.0 86.7 1.0 H A:CYS132 3.2 85.0 1.0 HB2 A:HIS103 3.3 80.0 1.0 HB3 A:HIS103 3.6 80.0 1.0 CB A:CYS118 3.7 82.9 1.0 CA A:CYS132 3.7 85.0 1.0 N A:CYS132 3.7 85.0 1.0 CB A:HIS103 3.9 80.0 1.0 SG A:CYS102 4.3 78.3 1.0 HB1 A:ALA130 4.3 83.1 1.0 HA A:CYS132 4.4 85.0 1.0 HA2 A:GLY113 4.4 83.8 1.0 HA A:HIS100 4.4 80.7 1.0 H A:SER131 4.4 83.9 1.0 HB2 A:HIS100 4.4 80.7 1.0 HB3 A:HIS100 4.6 80.7 1.0 H A:CYS118 4.6 82.9 1.0 CG A:HIS103 4.7 80.0 1.0 C A:CYS132 4.7 85.0 1.0 H A:LYS133 4.8 85.2 1.0 CB A:HIS100 4.9 80.7 1.0 H A:GLY113 4.9 83.8 1.0 C A:SER131 4.9 83.9 1.0 CA A:CYS118 5.0 82.9 1.0 SG A:CYS115 5.0 81.5 1.0

Iron binding site 3 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1004 b:83.3 occ:1.00 FE1 A:SF41004 0.0 83.3 1.0 H A:CYS216 2.2 82.9 1.0 S2 A:SF41004 2.3 83.3 1.0 S4 A:SF41004 2.3 83.3 1.0 S3 A:SF41004 2.3 83.3 1.0 SG A:CYS216 2.3 82.9 1.0 FE3 A:SF41004 2.7 83.3 1.0 FE4 A:SF41004 2.7 83.3 1.0 FE2 A:SF41004 2.7 83.3 1.0 H A:ILE214 3.0 80.8 1.0 N A:CYS216 3.0 82.9 1.0 H A:GLN215 3.2 83.6 1.0 CB A:CYS216 3.4 82.9 1.0 N A:GLN215 3.5 83.6 1.0 CG1 A:ILE214 3.6 80.8 1.0 N A:ILE214 3.6 80.8 1.0 HA A:CYS213 3.7 84.0 1.0 H A:ASN217 3.7 82.4 1.0 SG A:CYS213 3.8 84.0 1.0 CA A:CYS216 3.8 82.9 1.0 HA A:GLN215 3.8 83.6 1.0 S1 A:SF41004 3.9 83.3 1.0 C A:GLN215 4.0 83.6 1.0 CA A:GLN215 4.0 83.6 1.0 C A:ILE214 4.0 80.8 1.0 HD2 A:PRO267 4.2 80.3 1.0 CA A:ILE214 4.3 80.8 1.0 N A:ASN217 4.3 82.4 1.0 CA A:CYS213 4.4 84.0 1.0 C A:CYS213 4.4 84.0 1.0 C A:CYS216 4.4 82.9 1.0 CD1 A:ILE214 4.5 80.8 1.0 CB A:ILE214 4.5 80.8 1.0 HA A:CYS216 4.6 82.9 1.0 SG A:CYS266 4.6 80.2 1.0 H A:LEU218 4.6 82.0 1.0 CB A:CYS213 4.8 84.0 1.0 O A:ILE214 4.8 80.8 1.0 HG22 A:THR268 5.0 82.1 1.0 SG A:CYS219 5.0 83.2 1.0

Iron binding site 4 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1004 b:83.3 occ:1.00 FE2 A:SF41004 0.0 83.3 1.0 HA A:CYS213 2.2 84.0 1.0 S1 A:SF41004 2.3 83.3 1.0 S3 A:SF41004 2.3 83.3 1.0 S4 A:SF41004 2.3 83.3 1.0 SG A:CYS213 2.3 84.0 1.0 FE4 A:SF41004 2.7 83.3 1.0 FE1 A:SF41004 2.7 83.3 1.0 FE3 A:SF41004 2.7 83.3 1.0 CB A:CYS213 2.9 84.0 1.0 CA A:CYS213 2.9 84.0 1.0 H A:ILE214 3.5 80.8 1.0 S2 A:SF41004 3.9 83.3 1.0 C A:CYS213 3.9 84.0 1.0 H A:GLN215 3.9 83.6 1.0 N A:ILE214 3.9 80.8 1.0 N A:CYS213 4.0 84.0 1.0 HG A:LEU210 4.1 85.1 1.0 SG A:CYS266 4.1 80.2 1.0 HB3 A:ALA270 4.1 83.6 1.0 HD11 A:LEU210 4.1 85.1 1.0 HD21 A:LEU210 4.2 85.1 1.0 HG1 A:THR268 4.3 82.1 1.0 H A:CYS213 4.4 84.0 1.0 O A:ALA212 4.4 82.6 1.0 C A:ALA212 4.6 82.6 1.0 H A:CYS216 4.6 82.9 1.0 N A:GLN215 4.6 83.6 1.0 HB1 A:ALA270 4.7 83.6 1.0 CB A:ALA270 4.8 83.6 1.0 HG12 A:VAL243 4.8 84.5 1.0 CG A:LEU210 4.8 85.1 1.0 HB2 A:ALA270 4.8 83.6 1.0 CD1 A:LEU210 4.8 85.1 1.0 HA A:GLN215 4.9 83.6 1.0 SG A:CYS216 4.9 82.9 1.0 OG1 A:THR268 4.9 82.1 1.0 SG A:CYS219 4.9 83.2 1.0 CD2 A:LEU210 4.9 85.1 1.0 O A:CYS213 4.9 84.0 1.0

Iron binding site 5 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1004 b:83.3 occ:1.00 FE3 A:SF41004 0.0 83.3 1.0 S4 A:SF41004 2.3 83.3 1.0 S2 A:SF41004 2.3 83.3 1.0 S1 A:SF41004 2.3 83.3 1.0 SG A:CYS266 2.3 80.2 1.0 FE4 A:SF41004 2.7 83.3 1.0 FE1 A:SF41004 2.7 83.3 1.0 FE2 A:SF41004 2.7 83.3 1.0 CB A:CYS266 3.0 80.2 1.0 SG A:CYS219 3.4 83.2 1.0 SG A:CYS216 3.5 82.9 1.0 CA A:CYS266 3.6 80.2 1.0 HD2 A:PRO267 3.6 80.3 1.0 S3 A:SF41004 3.9 83.3 1.0 HA A:CYS213 4.4 84.0 1.0 HB3 A:ALA270 4.4 83.6 1.0 HB3 A:LEU271 4.5 83.5 1.0 HB2 A:LEU271 4.5 83.5 1.0 CD A:PRO267 4.5 80.3 1.0 HD23 A:LEU271 4.6 83.5 1.0 HG1 A:THR268 4.6 82.1 1.0 H A:CYS219 4.6 83.2 1.0 C A:CYS266 4.6 80.2 1.0 OG1 A:THR268 4.7 82.1 1.0 H A:LEU271 4.7 83.5 1.0 N A:CYS266 4.7 80.2 1.0 H A:CYS216 4.7 82.9 1.0 H A:ILE214 4.8 80.8 1.0 SG A:CYS213 4.8 84.0 1.0 N A:PRO267 4.9 80.3 1.0 CB A:LEU271 5.0 83.5 1.0 HD3 A:PRO267 5.0 80.3 1.0

Iron binding site 6 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1004 b:83.3 occ:1.00 FE4 A:SF41004 0.0 83.3 1.0 S3 A:SF41004 2.3 83.3 1.0 S2 A:SF41004 2.3 83.3 1.0 S1 A:SF41004 2.3 83.3 1.0 FE3 A:SF41004 2.7 83.3 1.0 FE2 A:SF41004 2.7 83.3 1.0 FE1 A:SF41004 2.7 83.3 1.0 SG A:CYS219 2.9 83.2 1.0 SG A:CYS213 3.5 84.0 1.0 H A:ASN217 3.6 82.4 1.0 H A:CYS216 3.8 82.9 1.0 S4 A:SF41004 3.9 83.3 1.0 SG A:CYS216 4.0 82.9 1.0 H A:CYS219 4.0 83.2 1.0 HB A:VAL243 4.2 84.5 1.0 HG12 A:VAL243 4.3 84.5 1.0 CB A:CYS219 4.3 83.2 1.0 N A:ASN217 4.4 82.4 1.0 H A:LEU218 4.4 82.0 1.0 HA A:GLN215 4.4 83.6 1.0 HA A:ASN217 4.5 82.4 1.0 N A:CYS216 4.5 82.9 1.0 HG22 A:VAL243 4.5 84.5 1.0 H A:GLN215 4.6 83.6 1.0 HA A:CYS213 4.7 84.0 1.0 N A:CYS219 4.8 83.2 1.0 CB A:VAL243 4.9 84.5 1.0 SG A:CYS266 4.9 80.2 1.0 CA A:ASN217 4.9 82.4 1.0 HD11 A:LEU210 5.0 85.1 1.0 N A:LEU218 5.0 82.0 1.0

Iron binding site 7 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1005 b:81.7 occ:1.00 FE1 A:SF41005 0.0 81.7 1.0 HG A:CYS262 1.8 80.7 1.0 S4 A:SF41005 2.3 81.7 1.0 S3 A:SF41005 2.3 81.7 1.0 S2 A:SF41005 2.3 81.7 1.0 SG A:CYS262 2.3 80.7 1.0 SG A:CYS223 2.6 81.0 1.0 FE2 A:SF41005 2.7 81.7 1.0 FE4 A:SF41005 2.7 81.7 1.0 FE3 A:SF41005 2.7 81.7 1.0 HB3 A:CYS262 3.1 80.7 1.0 CB A:CYS262 3.3 80.7 1.0 H A:CYS262 3.4 80.7 1.0 HD12 A:ILE232 3.5 83.8 1.0 O A:CYS259 3.6 78.5 1.0 S1 A:SF41005 3.9 81.7 1.0 HB2 A:CYS262 4.0 80.7 1.0 SG A:CYS259 4.0 78.5 1.0 N A:CYS262 4.1 80.7 1.0 H A:GLU261 4.1 79.8 1.0 CB A:CYS223 4.1 81.0 1.0 HD13 A:ILE232 4.1 83.8 1.0 CD1 A:ILE232 4.2 83.8 1.0 CA A:CYS262 4.3 80.7 1.0 C A:CYS259 4.7 78.5 1.0 HD11 A:ILE232 4.8 83.8 1.0 SG A:CYS256 4.8 83.0 1.0 H A:CYS259 4.8 78.5 1.0 HA2 A:GLY260 4.9 78.2 1.0 N A:GLU261 4.9 79.8 1.0 HE3 A:MET206 4.9 84.9 1.0 HE2 A:PHE245 4.9 87.6 1.0 HA A:CYS223 4.9 81.0 1.0 HB3 A:GLU261 5.0 79.8 1.0 HG13 A:ILE232 5.0 83.8 1.0

Iron binding site 8 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1005 b:81.7 occ:1.00 FE2 A:SF41005 0.0 81.7 1.0 S3 A:SF41005 2.3 81.7 1.0 S4 A:SF41005 2.3 81.7 1.0 S1 A:SF41005 2.3 81.7 1.0 SG A:CYS256 2.3 83.0 1.0 FE4 A:SF41005 2.7 81.7 1.0 FE1 A:SF41005 2.7 81.7 1.0 FE3 A:SF41005 2.7 81.7 1.0 CB A:CYS256 3.3 83.0 1.0 CA A:CYS256 3.7 83.0 1.0 H A:CYS259 3.8 78.5 1.0 S2 A:SF41005 3.9 81.7 1.0 SG A:CYS223 3.9 81.0 1.0 HE2 A:PHE245 3.9 87.6 1.0 SG A:CYS259 3.9 78.5 1.0 HG A:CYS262 3.9 80.7 1.0 N A:VAL257 4.1 77.2 1.0 C A:CYS256 4.3 83.0 1.0 N A:ALA258 4.4 76.0 1.0 HD12 A:ILE232 4.4 83.8 1.0 SG A:CYS262 4.5 80.7 1.0 N A:CYS259 4.5 78.5 1.0 HE3 A:MET206 4.6 84.9 1.0 O A:CYS259 4.7 78.5 1.0 HG22 A:VAL231 4.7 84.7 1.0 HG12 A:VAL231 4.7 84.7 1.0 CE2 A:PHE245 4.8 87.6 1.0 N A:CYS256 4.9 83.0 1.0 HB A:VAL231 4.9 84.7 1.0 CA A:ALA258 4.9 76.0 1.0

Iron binding site 9 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1005 b:81.7 occ:1.00 FE3 A:SF41005 0.0 81.7 1.0 O A:CYS259 2.1 78.5 1.0 H A:CYS259 2.1 78.5 1.0 S2 A:SF41005 2.3 81.7 1.0 S1 A:SF41005 2.3 81.7 1.0 S4 A:SF41005 2.3 81.7 1.0 SG A:CYS259 2.3 78.5 1.0 N A:CYS259 2.5 78.5 1.0 C A:CYS259 2.5 78.5 1.0 FE4 A:SF41005 2.7 81.7 1.0 FE2 A:SF41005 2.7 81.7 1.0 FE1 A:SF41005 2.7 81.7 1.0 CA A:CYS259 2.8 78.5 1.0 CB A:CYS259 3.1 78.5 1.0 HG A:CYS262 3.3 80.7 1.0 C A:ALA258 3.5 76.0 1.0 N A:GLY260 3.6 78.2 1.0 H A:GLU261 3.7 79.8 1.0 HA2 A:GLY260 3.8 78.2 1.0 S3 A:SF41005 3.9 81.7 1.0 CA A:ALA258 4.1 76.0 1.0 N A:ALA258 4.1 76.0 1.0 SG A:CYS256 4.1 83.0 1.0 CA A:GLY260 4.2 78.2 1.0 HE3 A:MET206 4.2 84.9 1.0 H A:GLY260 4.3 78.2 1.0 SG A:CYS223 4.3 81.0 1.0 H A:CYS262 4.4 80.7 1.0 SG A:CYS262 4.4 80.7 1.0 HE2 A:MET206 4.4 84.9 1.0 N A:GLU261 4.5 79.8 1.0 O A:ALA258 4.5 76.0 1.0 CE A:MET206 4.7 84.9 1.0 HE1 A:MET206 4.7 84.9 1.0 C A:VAL257 4.8 77.2 1.0 N A:VAL257 4.9 77.2 1.0 C A:GLY260 4.9 78.2 1.0 HD21 A:ASN229 5.0 84.7 1.0 CG2 A:VAL257 5.0 77.2 1.0

Iron binding site 10 out of 20 in the Dehydrogenase Holoenzyme


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Dehydrogenase Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1005 b:81.7 occ:1.00 FE4 A:SF41005 0.0 81.7 1.0 SG A:CYS259 2.2 78.5 1.0 SG A:CYS223 2.3 81.0 1.0 S3 A:SF41005 2.3 81.7 1.0 S2 A:SF41005 2.3 81.7 1.0 S1 A:SF41005 2.3 81.7 1.0 FE2 A:SF41005 2.7 81.7 1.0 FE3 A:SF41005 2.7 81.7 1.0 FE1 A:SF41005 2.7 81.7 1.0 HD21 A:ASN229 3.1 84.7 1.0 S4 A:SF41005 3.9 81.7 1.0 HB2 A:ASN229 3.9 84.7 1.0 H A:CYS259 3.9 78.5 1.0 CB A:CYS223 4.0 81.0 1.0 O A:CYS259 4.0 78.5 1.0 ND2 A:ASN229 4.0 84.7 1.0 CB A:CYS259 4.0 78.5 1.0 HA A:CYS223 4.1 81.0 1.0 HD22 A:ASN229 4.4 84.7 1.0 HG A:CYS262 4.4 80.7 1.0 HG22 A:VAL231 4.5 84.7 1.0 CA A:CYS223 4.6 81.0 1.0 N A:CYS259 4.6 78.5 1.0 CA A:CYS259 4.7 78.5 1.0 HG23 A:VAL231 4.7 84.7 1.0 O A:GLN227 4.7 81.1 1.0 HB3 A:GLN227 4.8 81.1 1.0 C A:CYS259 4.8 78.5 1.0 HG3 A:GLN227 4.8 81.1 1.0 HB A:VAL231 4.8 84.7 1.0 CB A:ASN229 4.8 84.7 1.0 SG A:CYS256 4.8 83.0 1.0 HG2 A:GLN227 4.9 81.1 1.0 CG A:ASN229 4.9 84.7 1.0 N A:VAL257 4.9 77.2 1.0 CG2 A:VAL257 4.9 77.2 1.0 HD12 A:ILE232 5.0 83.8 1.0 CG2 A:VAL231 5.0 84.7 1.0

S.H.Roh, J.S.Park. Dehydrogenase Holoenzyme To Be Published.