Iron in PDB 7eys: Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D

The structure of Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D, PDB code: 7eys was solved by H.Tao, T.Mori, I.Abe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.70 / 1.95
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	49.366, 72.227, 77.606, 81.58, 85.58, 70.24
R / Rfree (%)	21.3 / 26.8

The binding sites of Iron atom in the Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D (pdb code 7eys). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D, PDB code: 7eys:

Iron binding site 1 out of 1 in the Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Complex Structure of Sptf with Fe, Alpha-Ketoglutarate, and Andiconin D within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe303 b:28.0 occ:0.30 O2 C:AKG301 1.9 29.9 0.8 O C:HOH446 2.0 29.5 1.0 NE2 C:HIS205 2.2 27.2 1.0 O5 C:AKG301 2.2 29.3 0.8 OD1 C:ASP130 2.2 21.8 1.0 C1 C:AKG301 2.7 31.2 0.8 C2 C:AKG301 2.8 31.5 0.8 NE2 C:HIS128 2.9 27.1 1.0 CE1 C:HIS205 3.1 26.8 1.0 CG C:ASP130 3.1 23.8 1.0 CD2 C:HIS205 3.2 22.2 1.0 OD2 C:ASP130 3.3 26.2 1.0 CE1 C:HIS128 3.7 27.6 1.0 O C:HOH484 3.7 35.8 1.0 O1 C:AKG301 3.8 33.4 0.8 CD2 C:HIS128 3.9 25.9 1.0 C3 C:AKG301 4.1 29.4 0.8 ND1 C:HIS205 4.2 25.2 1.0 CAQ C:0CC302 4.3 29.0 0.7 CG C:HIS205 4.3 25.0 1.0 CAV C:0CC302 4.3 29.1 0.7 CB C:ASP130 4.5 23.1 1.0 CAZ C:0CC302 4.7 27.6 0.7 C4 C:AKG301 4.7 32.0 0.8 ND1 C:HIS128 4.8 27.7 1.0 CD1 C:LEU199 4.9 23.5 1.0 CAA C:0CC302 4.9 28.5 0.7 CA C:ASP130 4.9 19.9 1.0 CG C:HIS128 4.9 29.0 1.0 CAP C:0CC302 4.9 28.5 0.7 OBA C:0CC302 5.0 26.0 0.7

H.Tao, T.Mori, H.Chen, S.Lyu, A.Nonoyama, S.Lee, I.Abe. Molecular Insights Into the Unusually Promiscuous and Catalytically Versatile Fe(II)/ Alpha-Ketoglutarate-Dependent Oxygenase Sptf. Nat Commun V. 13 95 2022.
ISSN: ESSN 2041-1723
PubMed: 35013177
DOI: 10.1038/S41467-021-27636-3