Iron in PDB 7k8g: Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate

All present enzymatic activity of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate:
3.1.1.64; 5.3.3.22;

The structure of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate, PDB code: 7k8g was solved by P.D.Kiser, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.88 / 1.95
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	175.511, 175.511, 86.657, 90, 90, 120
R / Rfree (%)	19.4 / 21.1

The structure of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate also contains other interesting chemical elements:

Fluorine

(F)

2 atoms

The binding sites of Iron atom in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate (pdb code 7k8g). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate, PDB code: 7k8g:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:30.4 occ:1.00 O2 A:PLM602 2.0 56.2 0.5 O2 A:PLM602 2.0 43.9 0.5 NE2 A:HIS180 2.2 30.0 1.0 NE2 A:HIS313 2.2 29.3 1.0 NE2 A:HIS527 2.2 31.6 1.0 NE2 A:HIS241 2.2 30.8 1.0 C1 A:PLM602 2.9 57.4 0.5 CD2 A:HIS313 3.0 29.2 1.0 CD2 A:HIS527 3.1 31.9 1.0 CE1 A:HIS527 3.1 32.3 1.0 CD2 A:HIS180 3.1 30.4 1.0 CE1 A:HIS180 3.1 30.4 1.0 CD2 A:HIS241 3.1 30.1 1.0 C1 A:PLM602 3.2 45.1 0.5 CE1 A:HIS241 3.2 30.8 1.0 CE1 A:HIS313 3.2 29.3 1.0 C2 A:PLM602 3.2 57.2 0.5 O1 A:PLM602 3.8 45.5 0.5 O1 A:PLM602 4.1 58.2 0.5 C4 A:PLM602 4.1 57.1 0.5 CG A:HIS527 4.2 32.3 1.0 ND1 A:HIS527 4.2 32.2 1.0 CG A:HIS313 4.2 28.8 1.0 ND1 A:HIS180 4.2 30.8 1.0 C3 A:PLM602 4.3 57.5 0.5 ND1 A:HIS313 4.3 29.2 1.0 ND1 A:HIS241 4.3 30.1 1.0 CG A:HIS180 4.3 30.7 1.0 CG A:HIS241 4.3 30.0 1.0 C2 A:PLM602 4.3 45.5 0.5 C4 A:PLM602 4.8 45.9 0.5 CG1 A:VAL134 4.8 34.2 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Bovine RPE65 in Complex with 4-Fluoro-Mb-004 and Palmitate within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe601 b:28.1 occ:1.00 O2 B:PLM602 2.0 45.1 0.5 O2 B:PLM602 2.0 43.7 0.5 NE2 B:HIS180 2.2 31.0 1.0 NE2 B:HIS527 2.2 30.6 1.0 NE2 B:HIS313 2.2 28.5 1.0 NE2 B:HIS241 2.2 30.1 1.0 C1 B:PLM602 2.8 45.2 0.5 C1 B:PLM602 2.9 45.6 0.5 O1 B:PLM602 3.0 46.2 0.5 CD2 B:HIS527 3.1 30.3 1.0 CD2 B:HIS313 3.1 28.5 1.0 CE1 B:HIS527 3.1 30.7 1.0 CD2 B:HIS180 3.1 30.2 1.0 CD2 B:HIS241 3.2 29.5 1.0 CE1 B:HIS180 3.2 31.4 1.0 CE1 B:HIS241 3.2 30.3 1.0 C2 B:PLM602 3.2 45.4 0.5 CE1 B:HIS313 3.2 28.3 1.0 O1 B:PLM602 4.0 45.5 0.5 CG B:HIS527 4.2 30.6 1.0 ND1 B:HIS527 4.2 30.5 1.0 C2 B:PLM602 4.2 45.7 0.5 CG B:HIS313 4.2 27.9 1.0 ND1 B:HIS180 4.3 31.2 1.0 ND1 B:HIS241 4.3 29.9 1.0 ND1 B:HIS313 4.3 27.8 1.0 CG B:HIS180 4.3 30.8 1.0 CG B:HIS241 4.3 29.8 1.0 C4 B:PLM602 4.3 45.5 0.5 C3 B:PLM602 4.3 45.7 0.5 C4 B:PLM602 4.6 46.4 0.5 CG1 B:VAL134 4.8 32.1 1.0 C3 B:PLM602 4.9 46.0 0.5

P.D.Kiser, P.D.Kiser. N/A N/A.