Iron in PDB 7kcm: Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp

The structure of Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp also contains other interesting chemical elements:

Potassium	(K)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Iron atom in the Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp (pdb code 7kcm). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp, PDB code: 7kcm:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe201 b:163.0 occ:1.00 FE1 C:FES201 0.0 163.0 1.0 S2 C:FES201 2.2 163.0 1.0 S1 C:FES201 2.2 163.0 1.0 SG C:CYS113 2.3 144.0 1.0 SG C:CYS101 2.3 137.3 1.0 FE2 C:FES201 2.7 163.0 1.0 CB C:CYS101 3.1 137.3 1.0 CB C:CYS113 3.4 144.0 1.0 N C:GLY96 3.8 134.7 1.0 N C:CYS101 4.1 137.3 1.0 N C:GLU95 4.1 141.3 1.0 N C:ARG94 4.2 143.3 1.0 CA C:GLY96 4.2 134.7 1.0 CA C:ARG94 4.2 143.3 1.0 CA C:CYS101 4.2 137.3 1.0 SG C:CYS98 4.3 140.5 1.0 CD1 C:LEU111 4.4 130.4 1.0 SG C:CYS93 4.5 147.1 1.0 C C:ARG94 4.6 143.3 1.0 CD2 C:LEU73 4.7 140.4 1.0 CA C:CYS113 4.7 144.0 1.0 C C:GLU95 4.8 141.3 1.0 CG C:LEU111 4.8 130.4 1.0 N C:CYS113 4.9 144.0 1.0 N C:GLY99 4.9 134.5 1.0 CD2 C:LEU111 4.9 130.4 1.0 N C:ILE97 5.0 135.8 1.0 N C:SER100 5.0 136.7 1.0

Iron binding site 2 out of 2 in the Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Full-Length Human Mitochondrial HSP90 (TRAP1) in Complex with Sdhb in the Presence of Amp-Pnp within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe201 b:163.0 occ:1.00 FE2 C:FES201 0.0 163.0 1.0 S1 C:FES201 2.2 163.0 1.0 S2 C:FES201 2.2 163.0 1.0 SG C:CYS98 2.3 140.5 1.0 SG C:CYS93 2.3 147.1 1.0 FE1 C:FES201 2.7 163.0 1.0 CB C:CYS98 3.3 140.5 1.0 N C:CYS98 3.3 140.5 1.0 N C:CYS93 3.5 147.1 1.0 CB C:CYS93 3.8 147.1 1.0 CA C:CYS98 3.8 140.5 1.0 N C:GLY99 4.0 134.5 1.0 CA C:CYS93 4.0 147.1 1.0 N C:ARG94 4.0 143.3 1.0 N C:ILE97 4.0 135.8 1.0 SG C:CYS101 4.0 137.3 1.0 C C:CYS93 4.2 147.1 1.0 N C:SER92 4.3 148.2 1.0 N C:GLY96 4.3 134.7 1.0 C C:CYS98 4.3 140.5 1.0 C C:ILE97 4.5 135.8 1.0 C C:SER92 4.6 148.2 1.0 N C:GLU95 4.6 141.3 1.0 N C:SER100 4.6 136.7 1.0 CB C:SER92 4.7 148.2 1.0 SG C:CYS113 4.7 144.0 1.0 CA C:SER92 4.7 148.2 1.0 CA C:GLY96 4.7 134.7 1.0 CA C:ILE97 4.8 135.8 1.0 C C:GLY96 4.8 134.7 1.0 CA C:ARG94 4.9 143.3 1.0

Y.X.Liu, D.A.Agard, D.Elnatan, M.Sun, A.G.Myasnikov. Cryo-Em Reveals the Dynamic Interplay Between Mitochondrial HSP90 and Sdhb Folding Intermediates To Be Published.