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Iron in PDB 7ls4: Co-Complex CYP46A1 with 9129 (1B)Enzymatic activity of Co-Complex CYP46A1 with 9129 (1B)
All present enzymatic activity of Co-Complex CYP46A1 with 9129 (1B):
1.14.14.25; Protein crystallography data
The structure of Co-Complex CYP46A1 with 9129 (1B), PDB code: 7ls4
was solved by
W.Lane,
J.Yano,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Co-Complex CYP46A1 with 9129 (1B)
(pdb code 7ls4). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Co-Complex CYP46A1 with 9129 (1B), PDB code: 7ls4: Iron binding site 1 out of 1 in 7ls4Go back to Iron Binding Sites List in 7ls4
Iron binding site 1 out
of 1 in the Co-Complex CYP46A1 with 9129 (1B)
Mono view Stereo pair view
Reference:
T.Koike,
M.Yoshikawa,
H.K.Ando,
W.Farnaby,
T.Nishi,
E.Watanabe,
J.Yano,
M.Miyamoto,
S.Kondo,
T.Ishii,
T.Kuroita.
Discovery of Soticlestat, A Potent and Selective Inhibitor For Cholesterol 24-Hydroxylase (CH24H). J.Med.Chem. 2021.
Page generated: Fri Sep 24 14:09:52 2021
ISSN: ISSN 0022-2623 PubMed: 34387987 DOI: 10.1021/ACS.JMEDCHEM.1C00864 |
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