Iron in PDB 7m32: Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Enzymatic activity of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
All present enzymatic activity of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically:
1.3.1.2;
Protein crystallography data
The structure of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically, PDB code: 7m32
was solved by
A.Butrin,
B.Beaupre,
D.Forouzesh,
D.Liu,
G.Moran,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
47.26 /
1.82
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
81.87,
158.73,
162.7,
90,
95.89,
90
|
R / Rfree (%)
|
16.9 /
20.2
|
Iron Binding Sites:
Iron binding site 1 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 1 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1101
b:22.6
occ:1.00
|
FE1
|
A:SF41101
|
0.0
|
22.6
|
1.0
|
S4
|
A:SF41101
|
2.3
|
21.7
|
1.0
|
S2
|
A:SF41101
|
2.3
|
22.4
|
1.0
|
S3
|
A:SF41101
|
2.3
|
22.0
|
1.0
|
SG
|
A:CYS130
|
2.3
|
25.4
|
1.0
|
FE2
|
A:SF41101
|
2.7
|
22.3
|
1.0
|
FE4
|
A:SF41101
|
2.7
|
21.3
|
1.0
|
FE3
|
A:SF41101
|
2.7
|
23.2
|
1.0
|
CB
|
A:CYS130
|
3.2
|
23.3
|
1.0
|
S1
|
A:SF41101
|
3.9
|
20.4
|
1.0
|
CG2
|
A:VAL490
|
4.3
|
22.1
|
1.0
|
CB
|
A:CYS126
|
4.3
|
20.2
|
1.0
|
CB
|
A:VAL490
|
4.4
|
18.9
|
1.0
|
O
|
A:CYS126
|
4.4
|
25.9
|
1.0
|
OE1
|
A:GLN156
|
4.5
|
21.1
|
1.0
|
CG1
|
A:VAL490
|
4.6
|
22.5
|
1.0
|
NE2
|
A:GLN156
|
4.7
|
21.9
|
1.0
|
CA
|
A:CYS130
|
4.7
|
22.1
|
1.0
|
C
|
A:CYS126
|
4.7
|
25.3
|
1.0
|
SG
|
A:CYS136
|
4.8
|
21.3
|
1.0
|
SG
|
A:CYS91
|
4.8
|
23.3
|
1.0
|
CD1
|
A:LEU135
|
4.9
|
28.0
|
1.0
|
CD
|
A:GLN156
|
5.0
|
25.4
|
1.0
|
|
Iron binding site 2 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 2 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1101
b:22.3
occ:1.00
|
FE2
|
A:SF41101
|
0.0
|
22.3
|
1.0
|
S4
|
A:SF41101
|
2.3
|
21.7
|
1.0
|
SG
|
A:CYS136
|
2.3
|
21.3
|
1.0
|
S1
|
A:SF41101
|
2.3
|
20.4
|
1.0
|
S3
|
A:SF41101
|
2.3
|
22.0
|
1.0
|
FE3
|
A:SF41101
|
2.7
|
23.2
|
1.0
|
FE1
|
A:SF41101
|
2.7
|
22.6
|
1.0
|
FE4
|
A:SF41101
|
2.7
|
21.3
|
1.0
|
CB
|
A:CYS136
|
3.2
|
25.6
|
1.0
|
S2
|
A:SF41101
|
3.9
|
22.4
|
1.0
|
CG2
|
A:ILE152
|
4.2
|
18.1
|
1.0
|
CG2
|
A:THR132
|
4.2
|
22.1
|
1.0
|
N
|
A:CYS136
|
4.4
|
24.8
|
1.0
|
CA
|
A:CYS136
|
4.4
|
22.5
|
1.0
|
OE1
|
A:GLN156
|
4.4
|
21.1
|
1.0
|
SG
|
A:CYS91
|
4.7
|
23.3
|
1.0
|
SG
|
A:CYS130
|
4.7
|
25.4
|
1.0
|
CB
|
A:CYS91
|
4.8
|
19.7
|
1.0
|
CB
|
A:CYS130
|
4.8
|
23.3
|
1.0
|
CB
|
A:ILE152
|
5.0
|
20.8
|
1.0
|
|
Iron binding site 3 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 3 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1101
b:23.2
occ:1.00
|
FE3
|
A:SF41101
|
0.0
|
23.2
|
1.0
|
OE1
|
A:GLN156
|
2.0
|
21.1
|
1.0
|
S1
|
A:SF41101
|
2.3
|
20.4
|
1.0
|
S4
|
A:SF41101
|
2.3
|
21.7
|
1.0
|
S2
|
A:SF41101
|
2.3
|
22.4
|
1.0
|
FE2
|
A:SF41101
|
2.7
|
22.3
|
1.0
|
FE4
|
A:SF41101
|
2.7
|
21.3
|
1.0
|
FE1
|
A:SF41101
|
2.7
|
22.6
|
1.0
|
CD
|
A:GLN156
|
2.9
|
25.4
|
1.0
|
NE2
|
A:GLN156
|
3.2
|
21.9
|
1.0
|
CD2
|
A:LEU95
|
3.7
|
24.6
|
1.0
|
S3
|
A:SF41101
|
3.9
|
22.0
|
1.0
|
CG
|
A:GLN156
|
4.3
|
22.4
|
1.0
|
CB
|
A:GLN156
|
4.5
|
19.0
|
1.0
|
CG2
|
A:ILE152
|
4.6
|
18.1
|
1.0
|
SG
|
A:CYS91
|
4.7
|
23.3
|
1.0
|
SG
|
A:CYS136
|
4.8
|
21.3
|
1.0
|
SG
|
A:CYS130
|
4.8
|
25.4
|
1.0
|
CG
|
A:LEU95
|
4.9
|
36.0
|
1.0
|
|
Iron binding site 4 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 4 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1101
b:21.3
occ:1.00
|
FE4
|
A:SF41101
|
0.0
|
21.3
|
1.0
|
SG
|
A:CYS91
|
2.3
|
23.3
|
1.0
|
S2
|
A:SF41101
|
2.3
|
22.4
|
1.0
|
S1
|
A:SF41101
|
2.3
|
20.4
|
1.0
|
S3
|
A:SF41101
|
2.3
|
22.0
|
1.0
|
FE3
|
A:SF41101
|
2.7
|
23.2
|
1.0
|
FE2
|
A:SF41101
|
2.7
|
22.3
|
1.0
|
FE1
|
A:SF41101
|
2.7
|
22.6
|
1.0
|
CB
|
A:CYS91
|
3.3
|
19.7
|
1.0
|
S4
|
A:SF41101
|
3.9
|
21.7
|
1.0
|
CA
|
A:CYS91
|
4.0
|
25.4
|
1.0
|
OG1
|
A:THR93
|
4.1
|
25.8
|
1.0
|
CG2
|
A:VAL490
|
4.4
|
22.1
|
1.0
|
CD2
|
A:LEU95
|
4.5
|
24.6
|
1.0
|
OE1
|
A:GLN156
|
4.5
|
21.1
|
1.0
|
CD1
|
A:LEU95
|
4.6
|
37.0
|
1.0
|
CB
|
A:LEU95
|
4.6
|
21.7
|
1.0
|
CD
|
A:PRO92
|
4.6
|
19.1
|
1.0
|
SG
|
A:CYS136
|
4.7
|
21.3
|
1.0
|
C
|
A:CYS91
|
4.7
|
23.4
|
1.0
|
CB
|
A:CYS136
|
4.7
|
25.6
|
1.0
|
CG
|
A:LEU95
|
4.8
|
36.0
|
1.0
|
N
|
A:PRO92
|
4.8
|
23.1
|
1.0
|
SG
|
A:CYS130
|
4.9
|
25.4
|
1.0
|
|
Iron binding site 5 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 5 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 5 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1102
b:21.7
occ:1.00
|
FE1
|
A:SF41102
|
0.0
|
21.7
|
1.0
|
S4
|
A:SF41102
|
2.2
|
20.9
|
1.0
|
SG
|
A:CYS140
|
2.3
|
20.0
|
1.0
|
S2
|
A:SF41102
|
2.3
|
21.4
|
1.0
|
S3
|
A:SF41102
|
2.3
|
21.8
|
1.0
|
FE4
|
A:SF41102
|
2.7
|
21.9
|
1.0
|
FE3
|
A:SF41102
|
2.7
|
20.6
|
1.0
|
FE2
|
A:SF41102
|
2.8
|
20.4
|
1.0
|
CB
|
A:CYS140
|
3.4
|
18.6
|
1.0
|
CA
|
A:CYS140
|
3.8
|
24.2
|
1.0
|
S1
|
A:SF41102
|
3.9
|
23.4
|
1.0
|
N
|
A:ASN141
|
3.9
|
24.0
|
1.0
|
CG1
|
A:ILE150
|
4.1
|
20.9
|
1.0
|
C
|
A:CYS140
|
4.2
|
23.4
|
1.0
|
CB
|
A:ILE150
|
4.4
|
21.3
|
1.0
|
N
|
A:LEU142
|
4.4
|
20.6
|
1.0
|
SG
|
A:CYS87
|
4.7
|
21.1
|
1.0
|
CB
|
A:LEU142
|
4.8
|
23.6
|
1.0
|
SG
|
A:CYS82
|
4.9
|
21.2
|
1.0
|
CB
|
A:CYS87
|
4.9
|
22.3
|
1.0
|
SG
|
A:CYS79
|
4.9
|
19.3
|
1.0
|
CA
|
A:ASN141
|
4.9
|
22.0
|
1.0
|
N
|
A:ILE150
|
4.9
|
22.9
|
1.0
|
CD1
|
A:LEU142
|
4.9
|
18.1
|
1.0
|
|
Iron binding site 6 out
of 64 in 7m32
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Iron Binding Sites List in 7m32
Iron binding site 6 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 6 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1102
b:20.4
occ:1.00
|
FE2
|
A:SF41102
|
0.0
|
20.4
|
1.0
|
S1
|
A:SF41102
|
2.3
|
23.4
|
1.0
|
S3
|
A:SF41102
|
2.3
|
21.8
|
1.0
|
S4
|
A:SF41102
|
2.3
|
20.9
|
1.0
|
SG
|
A:CYS82
|
2.3
|
21.2
|
1.0
|
FE4
|
A:SF41102
|
2.7
|
21.9
|
1.0
|
FE3
|
A:SF41102
|
2.7
|
20.6
|
1.0
|
FE1
|
A:SF41102
|
2.8
|
21.7
|
1.0
|
CB
|
A:CYS82
|
3.4
|
24.7
|
1.0
|
N
|
A:CYS82
|
3.9
|
23.8
|
1.0
|
S2
|
A:SF41102
|
3.9
|
21.4
|
1.0
|
CA
|
A:CYS82
|
4.3
|
23.4
|
1.0
|
N
|
A:LYS81
|
4.3
|
18.9
|
1.0
|
ND2
|
A:ASN141
|
4.3
|
22.6
|
1.0
|
SG
|
A:CYS79
|
4.5
|
19.3
|
1.0
|
CB
|
A:LEU80
|
4.5
|
15.5
|
1.0
|
CB
|
A:ASN141
|
4.7
|
22.5
|
1.0
|
N
|
A:LEU80
|
4.7
|
20.1
|
1.0
|
N
|
A:ASN141
|
4.7
|
24.0
|
1.0
|
SG
|
A:CYS87
|
4.7
|
21.1
|
1.0
|
CB
|
A:ALA85
|
4.8
|
23.4
|
1.0
|
SG
|
A:CYS140
|
4.8
|
20.0
|
1.0
|
C
|
A:LEU80
|
4.8
|
18.6
|
1.0
|
C
|
A:LYS81
|
4.9
|
22.9
|
1.0
|
CA
|
A:LYS81
|
4.9
|
23.6
|
1.0
|
CA
|
A:LEU80
|
4.9
|
18.8
|
1.0
|
CG
|
A:ASN141
|
4.9
|
21.3
|
1.0
|
CD
|
A:PRO86
|
4.9
|
23.9
|
1.0
|
|
Iron binding site 7 out
of 64 in 7m32
Go back to
Iron Binding Sites List in 7m32
Iron binding site 7 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 7 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1102
b:20.6
occ:1.00
|
FE3
|
A:SF41102
|
0.0
|
20.6
|
1.0
|
SG
|
A:CYS79
|
2.3
|
19.3
|
1.0
|
S2
|
A:SF41102
|
2.3
|
21.4
|
1.0
|
S1
|
A:SF41102
|
2.3
|
23.4
|
1.0
|
S4
|
A:SF41102
|
2.3
|
20.9
|
1.0
|
FE1
|
A:SF41102
|
2.7
|
21.7
|
1.0
|
FE2
|
A:SF41102
|
2.7
|
20.4
|
1.0
|
FE4
|
A:SF41102
|
2.7
|
21.9
|
1.0
|
CB
|
A:CYS79
|
3.5
|
24.0
|
1.0
|
S3
|
A:SF41102
|
3.9
|
21.8
|
1.0
|
CG1
|
A:ILE150
|
4.0
|
20.9
|
1.0
|
N
|
A:LEU80
|
4.0
|
20.1
|
1.0
|
CA
|
A:CYS79
|
4.1
|
20.3
|
1.0
|
N
|
A:LYS81
|
4.1
|
18.9
|
1.0
|
C
|
A:CYS79
|
4.4
|
20.7
|
1.0
|
CB
|
A:ILE150
|
4.6
|
21.3
|
1.0
|
CD1
|
A:ILE101
|
4.6
|
21.0
|
1.0
|
SG
|
A:CYS82
|
4.7
|
21.2
|
1.0
|
CA
|
A:LYS81
|
4.7
|
23.6
|
1.0
|
SG
|
A:CYS140
|
4.8
|
20.0
|
1.0
|
SG
|
A:CYS87
|
4.9
|
21.1
|
1.0
|
CG2
|
A:ILE150
|
5.0
|
20.3
|
1.0
|
CA
|
A:LEU80
|
5.0
|
18.8
|
1.0
|
CG2
|
A:ILE97
|
5.0
|
17.1
|
1.0
|
C
|
A:LEU80
|
5.0
|
18.6
|
1.0
|
|
Iron binding site 8 out
of 64 in 7m32
Go back to
Iron Binding Sites List in 7m32
Iron binding site 8 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 8 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1102
b:21.9
occ:1.00
|
FE4
|
A:SF41102
|
0.0
|
21.9
|
1.0
|
S1
|
A:SF41102
|
2.3
|
23.4
|
1.0
|
SG
|
A:CYS87
|
2.3
|
21.1
|
1.0
|
S2
|
A:SF41102
|
2.3
|
21.4
|
1.0
|
S3
|
A:SF41102
|
2.3
|
21.8
|
1.0
|
FE2
|
A:SF41102
|
2.7
|
20.4
|
1.0
|
FE1
|
A:SF41102
|
2.7
|
21.7
|
1.0
|
FE3
|
A:SF41102
|
2.7
|
20.6
|
1.0
|
CB
|
A:CYS87
|
3.3
|
22.3
|
1.0
|
S4
|
A:SF41102
|
3.9
|
20.9
|
1.0
|
CG2
|
A:ILE97
|
4.1
|
17.1
|
1.0
|
CB
|
A:ALA85
|
4.2
|
23.4
|
1.0
|
N
|
A:CYS87
|
4.4
|
19.4
|
1.0
|
CA
|
A:CYS87
|
4.5
|
20.2
|
1.0
|
SG
|
A:CYS79
|
4.7
|
19.3
|
1.0
|
SG
|
A:CYS140
|
4.7
|
20.0
|
1.0
|
CD1
|
A:ILE152
|
4.8
|
22.2
|
1.0
|
SG
|
A:CYS82
|
4.8
|
21.2
|
1.0
|
CB
|
A:ILE97
|
4.9
|
22.4
|
1.0
|
|
Iron binding site 9 out
of 64 in 7m32
Go back to
Iron Binding Sites List in 7m32
Iron binding site 9 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 9 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1103
b:22.2
occ:1.00
|
FE1
|
A:SF41103
|
0.0
|
22.2
|
1.0
|
S2
|
A:SF41103
|
2.3
|
22.1
|
1.0
|
SG
|
A:CYS953
|
2.3
|
21.9
|
1.0
|
S3
|
A:SF41103
|
2.3
|
21.9
|
1.0
|
S4
|
A:SF41103
|
2.3
|
19.8
|
1.0
|
FE3
|
A:SF41103
|
2.7
|
22.8
|
1.0
|
FE4
|
A:SF41103
|
2.7
|
21.3
|
1.0
|
FE2
|
A:SF41103
|
2.7
|
23.3
|
1.0
|
CB
|
A:CYS953
|
3.3
|
24.1
|
1.0
|
CA
|
A:CYS953
|
3.7
|
25.0
|
1.0
|
S1
|
A:SF41103
|
3.9
|
18.7
|
1.0
|
N
|
A:ASN955
|
3.9
|
17.4
|
1.0
|
N
|
A:ILE954
|
4.0
|
21.4
|
1.0
|
CG
|
A:PRO980
|
4.1
|
25.6
|
1.0
|
C
|
A:CYS953
|
4.3
|
22.1
|
1.0
|
CD
|
A:PRO980
|
4.5
|
23.2
|
1.0
|
SG
|
A:CYS1001
|
4.5
|
25.8
|
1.0
|
CA
|
A:ASN955
|
4.6
|
19.3
|
1.0
|
N
|
A:CYS956
|
4.7
|
20.9
|
1.0
|
SG
|
A:CYS959
|
4.8
|
22.5
|
1.0
|
SG
|
A:CYS996
|
4.8
|
20.0
|
1.0
|
C
|
A:ILE954
|
4.8
|
21.9
|
1.0
|
CG2
|
A:ILE948
|
5.0
|
25.7
|
1.0
|
SG
|
A:CYS956
|
5.0
|
22.9
|
1.0
|
N
|
A:CYS953
|
5.0
|
24.9
|
1.0
|
|
Iron binding site 10 out
of 64 in 7m32
Go back to
Iron Binding Sites List in 7m32
Iron binding site 10 out
of 64 in the Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 10 of Dihydropyrimidine Dehydrogenase (Dpd) C671A Mutant Soaked with Uracil and Nadph Anaerobically within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe1103
b:23.3
occ:1.00
|
FE2
|
A:SF41103
|
0.0
|
23.3
|
1.0
|
S1
|
A:SF41103
|
2.3
|
18.7
|
1.0
|
S4
|
A:SF41103
|
2.3
|
19.8
|
1.0
|
S3
|
A:SF41103
|
2.3
|
21.9
|
1.0
|
SG
|
A:CYS956
|
2.3
|
22.9
|
1.0
|
FE3
|
A:SF41103
|
2.7
|
22.8
|
1.0
|
FE1
|
A:SF41103
|
2.7
|
22.2
|
1.0
|
FE4
|
A:SF41103
|
2.8
|
21.3
|
1.0
|
N
|
A:CYS956
|
3.6
|
20.9
|
1.0
|
CB
|
A:CYS956
|
3.7
|
15.9
|
1.0
|
N
|
A:GLY957
|
3.8
|
19.1
|
1.0
|
S2
|
A:SF41103
|
3.9
|
22.1
|
1.0
|
CA
|
A:CYS956
|
4.0
|
18.1
|
1.0
|
N
|
A:LYS958
|
4.1
|
22.1
|
1.0
|
CD
|
A:PRO997
|
4.1
|
23.3
|
1.0
|
C
|
A:CYS956
|
4.2
|
20.4
|
1.0
|
N
|
A:ASN955
|
4.4
|
17.4
|
1.0
|
CG
|
A:PRO997
|
4.5
|
22.2
|
1.0
|
C
|
A:ASN955
|
4.6
|
21.8
|
1.0
|
SG
|
A:CYS953
|
4.6
|
21.9
|
1.0
|
CA
|
A:GLY957
|
4.7
|
19.7
|
1.0
|
SG
|
A:CYS959
|
4.7
|
22.5
|
1.0
|
SG
|
A:CYS996
|
4.7
|
20.0
|
1.0
|
CB
|
A:LYS958
|
4.7
|
18.4
|
1.0
|
N
|
A:CYS959
|
4.8
|
20.8
|
1.0
|
C
|
A:GLY957
|
4.8
|
20.6
|
1.0
|
CA
|
A:ASN955
|
4.9
|
19.3
|
1.0
|
CA
|
A:LYS958
|
4.9
|
19.3
|
1.0
|
C
|
A:ILE954
|
5.0
|
21.9
|
1.0
|
|
Reference:
B.A.Beaupre,
D.C.Forouzesh,
A.Butrin,
D.Liu,
G.R.Moran.
Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry 2021.
ISSN: ISSN 0006-2960
PubMed: 34032117
DOI: 10.1021/ACS.BIOCHEM.1C00243
Page generated: Thu Aug 8 08:10:55 2024
|