Iron in PDB 7n7i: X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens

The structure of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens, PDB code: 7n7i was solved by T.L.Grove, S.C.Almo, J.B.Bonanno, J.C.Lachowicz, A.G.Gizzi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.14 / 3.19
Space group	P 31
Cell size a, b, c (Å), α, β, γ (°)	85.943, 85.943, 111.718, 90, 90, 120
R / Rfree (%)	22.6 / 26

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Iron atom in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens (pdb code 7n7i). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 12 binding sites of Iron where determined in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens, PDB code: 7n7i:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe402 b:21.6 occ:1.00 FE1 A:SF4402 0.0 21.6 1.0 S3 A:SF4402 2.3 22.0 1.0 S2 A:SF4402 2.3 19.5 1.0 S4 A:SF4402 2.3 22.6 1.0 FE4 A:SF4402 2.7 21.5 1.0 FE2 A:SF4402 2.7 23.8 1.0 FE3 A:SF4402 2.7 22.3 1.0 SG A:CYS35 2.8 24.0 1.0 CB A:CYS35 3.3 25.6 1.0 S1 A:SF4402 3.9 21.7 1.0 N A:CYS35 4.0 27.0 1.0 NH2 A:ARG139 4.1 23.9 1.0 CB A:LYS33 4.1 24.6 1.0 CA A:CYS35 4.3 25.1 1.0 OXT A:SAM401 4.5 44.0 1.0 CZ A:ARG139 4.5 24.3 1.0 NH1 A:ARG139 4.6 23.8 1.0 SG A:CYS31 4.9 23.6 1.0 C A:LYS33 5.0 23.1 1.0 CG A:LYS33 5.0 25.9 1.0

Iron binding site 2 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe402 b:23.8 occ:1.00 FE2 A:SF4402 0.0 23.8 1.0 S4 A:SF4402 2.3 22.6 1.0 S1 A:SF4402 2.3 21.7 1.0 S3 A:SF4402 2.3 22.0 1.0 OXT A:SAM401 2.6 44.0 1.0 N A:SAM401 2.7 33.4 1.0 FE1 A:SF4402 2.7 21.6 1.0 FE3 A:SF4402 2.7 22.3 1.0 FE4 A:SF4402 2.7 21.5 1.0 C A:SAM401 3.3 39.6 1.0 CA A:SAM401 3.5 36.8 1.0 SD A:SAM401 3.7 43.6 1.0 S2 A:SF4402 3.9 19.5 1.0 CE A:SAM401 4.1 43.2 1.0 CG A:SAM401 4.1 39.7 1.0 CB A:SAM401 4.4 37.4 1.0 O A:GLY73 4.4 29.4 1.0 O A:SAM401 4.4 41.3 1.0 NH2 A:ARG139 4.9 23.9 1.0 SG A:CYS31 5.0 23.6 1.0

Iron binding site 3 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe402 b:22.3 occ:1.00 FE3 A:SF4402 0.0 22.3 1.0 S4 A:SF4402 2.3 22.6 1.0 S2 A:SF4402 2.3 19.5 1.0 S1 A:SF4402 2.3 21.7 1.0 FE4 A:SF4402 2.7 21.5 1.0 FE2 A:SF4402 2.7 23.8 1.0 FE1 A:SF4402 2.7 21.6 1.0 SG A:CYS38 2.9 23.9 1.0 CB A:CYS38 3.3 22.6 1.0 S3 A:SF4402 3.9 22.0 1.0 CA A:CYS38 4.0 22.8 1.0 CE A:SAM401 4.4 43.2 1.0 CB A:CYS35 4.7 25.6 1.0 C8 A:SAM401 4.9 17.4 1.0 N A:SAM401 4.9 33.4 1.0 N A:CYS38 5.0 23.1 1.0 C A:CYS38 5.0 23.2 1.0

Iron binding site 4 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe402 b:21.5 occ:1.00 FE4 A:SF4402 0.0 21.5 1.0 S2 A:SF4402 2.3 19.5 1.0 S1 A:SF4402 2.3 21.7 1.0 S3 A:SF4402 2.3 22.0 1.0 FE1 A:SF4402 2.7 21.6 1.0 FE3 A:SF4402 2.7 22.3 1.0 FE2 A:SF4402 2.7 23.8 1.0 SG A:CYS31 2.8 23.6 1.0 CB A:CYS31 3.4 20.1 1.0 S4 A:SF4402 3.9 22.6 1.0 N A:SAM401 4.0 33.4 1.0 CB A:LYS33 4.4 24.6 1.0 O A:LYS33 4.5 24.6 1.0 O A:GLY73 4.6 29.4 1.0 C A:GLY73 4.7 25.7 1.0 SG A:CYS38 4.8 23.9 1.0 C A:LYS33 4.8 23.1 1.0 OXT A:SAM401 4.9 44.0 1.0 CA A:CYS31 4.9 21.0 1.0 N A:LYS33 4.9 23.1 1.0 CA A:GLY73 4.9 25.1 1.0 CA A:LYS33 5.0 23.3 1.0

Iron binding site 5 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe402 b:27.1 occ:1.00 FE1 B:SF4402 0.0 27.1 1.0 S3 B:SF4402 2.3 27.1 1.0 S2 B:SF4402 2.3 25.9 1.0 S4 B:SF4402 2.3 29.4 1.0 FE4 B:SF4402 2.7 27.1 1.0 FE2 B:SF4402 2.7 31.2 1.0 FE3 B:SF4402 2.7 28.8 1.0 SG B:CYS35 2.9 31.0 1.0 CB B:CYS35 3.3 32.7 1.0 S1 B:SF4402 3.9 25.9 1.0 N B:CYS35 4.1 36.8 1.0 CB B:LYS33 4.2 36.7 1.0 NH2 B:ARG139 4.2 36.8 1.0 OXT B:SAM401 4.3 34.8 1.0 NH1 B:ARG139 4.3 36.9 1.0 CA B:CYS35 4.3 33.8 1.0 CZ B:ARG139 4.4 38.2 1.0 CG B:LYS33 5.0 39.8 1.0 CB B:CYS38 5.0 32.0 1.0

Iron binding site 6 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe402 b:31.2 occ:1.00 FE2 B:SF4402 0.0 31.2 1.0 S4 B:SF4402 2.3 29.4 1.0 S3 B:SF4402 2.3 27.1 1.0 S1 B:SF4402 2.3 25.9 1.0 OXT B:SAM401 2.6 34.8 1.0 N B:SAM401 2.7 32.4 1.0 FE1 B:SF4402 2.7 27.1 1.0 FE3 B:SF4402 2.7 28.8 1.0 FE4 B:SF4402 2.7 27.1 1.0 C B:SAM401 3.2 33.9 1.0 CA B:SAM401 3.5 34.8 1.0 SD B:SAM401 3.6 49.4 1.0 S2 B:SF4402 3.9 25.9 1.0 CG B:SAM401 4.0 44.5 1.0 CE B:SAM401 4.1 48.9 1.0 O B:GLY73 4.2 32.6 1.0 O B:SAM401 4.3 32.8 1.0 CB B:SAM401 4.3 39.0 1.0 SG B:CYS31 4.8 29.4 1.0 C B:GLY73 4.9 30.9 1.0 NH2 B:ARG139 5.0 36.8 1.0

Iron binding site 7 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe402 b:28.8 occ:1.00 FE3 B:SF4402 0.0 28.8 1.0 S2 B:SF4402 2.3 25.9 1.0 S1 B:SF4402 2.3 25.9 1.0 S4 B:SF4402 2.3 29.4 1.0 FE4 B:SF4402 2.7 27.1 1.0 FE1 B:SF4402 2.7 27.1 1.0 FE2 B:SF4402 2.7 31.2 1.0 SG B:CYS38 2.8 34.2 1.0 CB B:CYS38 3.2 32.0 1.0 S3 B:SF4402 3.9 27.1 1.0 CA B:CYS38 4.0 31.2 1.0 CE B:SAM401 4.3 48.9 1.0 C8 B:SAM401 4.8 28.8 1.0 CB B:CYS35 4.8 32.7 1.0 SD B:SAM401 4.9 49.4 1.0 N B:CYS38 4.9 31.5 1.0 O B:HIS40 4.9 31.8 1.0 C B:CYS38 5.0 30.0 1.0

Iron binding site 8 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe402 b:27.1 occ:1.00 FE4 B:SF4402 0.0 27.1 1.0 S2 B:SF4402 2.3 25.9 1.0 S3 B:SF4402 2.3 27.1 1.0 S1 B:SF4402 2.3 25.9 1.0 FE1 B:SF4402 2.7 27.1 1.0 FE3 B:SF4402 2.7 28.8 1.0 FE2 B:SF4402 2.7 31.2 1.0 SG B:CYS31 2.8 29.4 1.0 CB B:CYS31 3.4 30.0 1.0 S4 B:SF4402 3.9 29.4 1.0 N B:SAM401 4.2 32.4 1.0 O B:LYS33 4.3 33.9 1.0 CB B:LYS33 4.3 36.7 1.0 C B:LYS33 4.6 33.7 1.0 N B:LYS33 4.8 28.5 1.0 SG B:CYS38 4.8 34.2 1.0 O B:GLY73 4.8 32.6 1.0 CA B:LYS33 4.8 33.4 1.0 C B:GLY73 4.9 30.9 1.0 OXT B:SAM401 4.9 34.8 1.0 CA B:CYS31 4.9 29.2 1.0 CA B:GLY73 5.0 31.2 1.0

Iron binding site 9 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe402 b:90.9 occ:1.00 FE1 C:SF4402 0.0 90.9 1.0 S3 C:SF4402 2.3 93.8 1.0 S2 C:SF4402 2.3 92.0 1.0 S4 C:SF4402 2.3 90.3 1.0 FE2 C:SF4402 2.7 98.4 1.0 FE4 C:SF4402 2.7 86.0 1.0 FE3 C:SF4402 2.7 86.9 1.0 SG C:CYS35 3.0 87.8 1.0 CB C:CYS35 3.2 86.5 1.0 S1 C:SF4402 3.9 92.7 1.0 N C:CYS35 3.9 81.8 1.0 CB C:LYS33 4.1 72.5 1.0 CA C:CYS35 4.2 85.8 1.0 NH2 C:ARG139 4.5 77.2 1.0 NH1 C:ARG139 4.6 77.6 1.0 SG C:CYS31 4.7 70.3 1.0 CZ C:ARG139 4.7 79.0 1.0 OXT C:SAM401 4.8 92.8 1.0 CB C:CYS38 4.9 95.5 1.0 C C:LYS33 4.9 74.7 1.0 N C:GLU34 5.0 77.6 1.0

Iron binding site 10 out of 12 in the X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of X-Ray Crystal Structure of Viperin-Like Enzyme From Trichoderma Virens within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe402 b:98.4 occ:1.00 FE2 C:SF4402 0.0 98.4 1.0 S4 C:SF4402 2.3 90.3 1.0 S1 C:SF4402 2.3 92.7 1.0 S3 C:SF4402 2.3 93.8 1.0 OXT C:SAM401 2.6 92.8 1.0 FE3 C:SF4402 2.7 86.9 1.0 FE1 C:SF4402 2.7 90.9 1.0 FE4 C:SF4402 2.7 86.0 1.0 N C:SAM401 2.9 82.4 1.0 C C:SAM401 3.4 88.9 1.0 SD C:SAM401 3.6 90.0 1.0 CA C:SAM401 3.7 86.3 1.0 S2 C:SF4402 3.9 92.0 1.0 CG C:SAM401 4.2 89.1 1.0 CE C:SAM401 4.4 87.7 1.0 O C:SAM401 4.5 90.7 1.0 CB C:SAM401 4.5 87.9 1.0 C2' C:SAM401 4.6 82.0 1.0 NH2 C:ARG139 4.6 77.2 1.0 C8 C:SAM401 4.7 86.4 1.0 C3' C:SAM401 4.8 78.6 1.0 O C:GLY73 4.8 65.1 1.0 NH1 C:ARG139 4.9 77.6 1.0

J.C.Lachowicz, A.G.Gizzi, S.C.Almo, T.L.Grove. Structural Insight Into the Substrate Scope of Viperin and Viperin-Like Enzymes From Three Domains of Life To Be Published.