Iron in PDB 7o6y: Cryo-Em Structure of Respiratory Complex I Under Turnover

All present enzymatic activity of Cryo-Em Structure of Respiratory Complex I Under Turnover:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Cryo-Em Structure of Respiratory Complex I Under Turnover also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Cryo-Em Structure of Respiratory Complex I Under Turnover (pdb code 7o6y). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Cryo-Em Structure of Respiratory Complex I Under Turnover, PDB code: 7o6y:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:55.8 occ:1.00 FE1 A:SF4801 0.0 55.8 1.0 S3 A:SF4801 2.3 55.8 1.0 S2 A:SF4801 2.3 55.8 1.0 S4 A:SF4801 2.3 55.8 1.0 SG A:CYS133 2.3 33.1 1.0 FE2 A:SF4801 2.7 55.8 1.0 FE4 A:SF4801 2.7 55.8 1.0 FE3 A:SF4801 2.7 55.8 1.0 CB A:CYS133 3.3 33.1 1.0 CA A:CYS133 3.5 33.1 1.0 NE2 A:GLN145 3.7 26.7 1.0 S1 A:SF4801 3.9 55.8 1.0 N A:CYS133 3.9 33.1 1.0 CG A:GLN145 4.2 26.7 1.0 CE C:MET378 4.4 41.6 1.0 CD A:GLN145 4.4 26.7 1.0 NE2 A:HIS129 4.6 36.5 1.0 C A:ASP132 4.6 36.0 1.0 CB A:CYS136 4.6 31.2 1.0 SG A:CYS142 4.7 28.8 1.0 CG1 C:ILE382 4.8 55.8 1.0 C A:CYS133 4.9 33.1 1.0 SG A:CYS136 4.9 31.2 1.0 CD2 A:HIS129 5.0 36.5 1.0

Iron binding site 2 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:55.8 occ:1.00 FE2 A:SF4801 0.0 55.8 1.0 NE2 A:HIS129 2.1 36.5 1.0 S4 A:SF4801 2.3 55.8 1.0 S1 A:SF4801 2.3 55.8 1.0 S3 A:SF4801 2.3 55.8 1.0 FE3 A:SF4801 2.7 55.8 1.0 FE1 A:SF4801 2.7 55.8 1.0 FE4 A:SF4801 2.7 55.8 1.0 CD2 A:HIS129 3.0 36.5 1.0 CE1 A:HIS129 3.2 36.5 1.0 S2 A:SF4801 3.9 55.8 1.0 CG A:HIS129 4.2 36.5 1.0 ND1 A:HIS129 4.2 36.5 1.0 CD2 A:LEU144 4.5 21.1 1.0 SG A:CYS133 4.6 33.1 1.0 O A:PRO130 4.6 55.8 1.0 CG A:ARG182 4.7 28.5 1.0 SG A:CYS142 4.7 28.8 1.0 CE C:MET378 4.7 41.6 1.0 SG A:CYS136 4.8 31.2 1.0 CB A:ARG182 4.8 28.5 1.0 CD A:ARG182 5.0 28.5 1.0

Iron binding site 3 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:55.8 occ:1.00 FE3 A:SF4801 0.0 55.8 1.0 S1 A:SF4801 2.3 55.8 1.0 S4 A:SF4801 2.3 55.8 1.0 S2 A:SF4801 2.3 55.8 1.0 SG A:CYS136 2.3 31.2 1.0 CB A:CYS136 2.6 31.2 1.0 FE2 A:SF4801 2.7 55.8 1.0 FE4 A:SF4801 2.7 55.8 1.0 FE1 A:SF4801 2.7 55.8 1.0 S3 A:SF4801 3.9 55.8 1.0 CA A:CYS136 4.1 31.2 1.0 CB A:GLN138 4.4 31.9 1.0 CA A:CYS133 4.4 33.1 1.0 CD A:ARG182 4.5 28.5 1.0 O A:ASP132 4.6 36.0 1.0 N A:GLY236 4.6 27.9 1.0 N A:GLY139 4.7 30.1 1.0 N A:CYS133 4.7 33.1 1.0 C A:ASP132 4.7 36.0 1.0 C A:CYS136 4.7 31.2 1.0 NE2 A:HIS129 4.8 36.5 1.0 SG A:CYS133 4.8 33.1 1.0 NE A:ARG182 4.8 28.5 1.0 SG A:CYS142 4.9 28.8 1.0 N A:CYS136 4.9 31.2 1.0 CA A:GLY236 4.9 27.9 1.0 N A:GLN138 4.9 31.9 1.0 O A:CYS136 5.0 31.2 1.0

Iron binding site 4 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:55.8 occ:1.00 FE4 A:SF4801 0.0 55.8 1.0 S2 A:SF4801 2.3 55.8 1.0 S1 A:SF4801 2.3 55.8 1.0 S3 A:SF4801 2.3 55.8 1.0 SG A:CYS142 2.3 28.8 1.0 FE2 A:SF4801 2.7 55.8 1.0 FE3 A:SF4801 2.7 55.8 1.0 FE1 A:SF4801 2.7 55.8 1.0 CB A:CYS142 3.1 28.8 1.0 S4 A:SF4801 3.9 55.8 1.0 CG A:GLN145 4.4 26.7 1.0 NE2 A:HIS129 4.4 36.5 1.0 CB A:GLN138 4.4 31.9 1.0 SG A:CYS136 4.5 31.2 1.0 CA A:CYS142 4.5 28.8 1.0 CB A:LEU144 4.5 21.1 1.0 CG A:GLN138 4.7 31.9 1.0 NE2 A:GLN145 4.7 26.7 1.0 CD A:GLN145 4.7 26.7 1.0 N A:GLN145 4.8 26.7 1.0 CG1 A:VAL235 4.9 25.6 1.0 CB A:VAL235 4.9 25.6 1.0 CA A:VAL235 4.9 25.6 1.0 SG A:CYS133 4.9 33.1 1.0 N A:GLY236 4.9 27.9 1.0

Iron binding site 5 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:55.8 occ:1.00 FE1 A:SF4802 0.0 55.8 1.0 S2 A:SF4802 2.3 55.8 1.0 S3 A:SF4802 2.3 55.8 1.0 S4 A:SF4802 2.3 55.8 1.0 SG A:CYS233 2.3 28.8 1.0 FE3 A:SF4802 2.7 55.8 1.0 FE4 A:SF4802 2.7 55.8 1.0 FE2 A:SF4802 2.7 55.8 1.0 CB A:CYS233 3.2 28.8 1.0 CA A:CYS233 3.8 28.8 1.0 S1 A:SF4802 3.9 55.8 1.0 CB A:ALA237 4.1 28.6 1.0 CD1 A:LEU238 4.3 28.2 1.0 CD A:PRO234 4.4 27.4 1.0 SG A:CYS186 4.4 30.2 1.0 CG2 A:VAL235 4.5 25.6 1.0 C A:CYS233 4.6 28.8 1.0 CG A:LEU238 4.8 28.2 1.0 N A:PRO234 4.8 27.4 1.0 SG A:CYS189 4.9 31.2 1.0 N A:CYS233 4.9 28.8 1.0 SG A:CYS183 4.9 31.3 1.0 CB A:CYS189 5.0 31.2 1.0 N A:LEU238 5.0 28.2 1.0

Iron binding site 6 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:55.8 occ:1.00 FE2 A:SF4802 0.0 55.8 1.0 S1 A:SF4802 2.3 55.8 1.0 S4 A:SF4802 2.3 55.8 1.0 S3 A:SF4802 2.3 55.8 1.0 SG A:CYS183 2.3 31.3 1.0 FE3 A:SF4802 2.7 55.8 1.0 FE4 A:SF4802 2.7 55.8 1.0 FE1 A:SF4802 2.7 55.8 1.0 CB A:CYS183 3.2 31.3 1.0 CA A:CYS183 3.6 31.3 1.0 N A:HIS185 3.9 30.3 1.0 S2 A:SF4802 3.9 55.8 1.0 N A:ILE184 4.0 28.1 1.0 C A:CYS183 4.2 31.3 1.0 CA A:HIS185 4.3 30.3 1.0 CG1 A:ILE213 4.4 41.2 1.0 N A:CYS186 4.5 30.2 1.0 CB A:ALA237 4.6 28.6 1.0 CE A:MET180 4.7 31.1 1.0 SG A:CYS233 4.8 28.8 1.0 SG A:CYS189 4.8 31.2 1.0 CB A:ILE213 4.9 41.2 1.0 C A:ILE184 4.9 28.1 1.0 N A:CYS183 4.9 31.3 1.0 C A:HIS185 5.0 30.3 1.0 SG A:CYS186 5.0 30.2 1.0

Iron binding site 7 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:55.8 occ:1.00 FE3 A:SF4802 0.0 55.8 1.0 S4 A:SF4802 2.3 55.8 1.0 S2 A:SF4802 2.3 55.8 1.0 S1 A:SF4802 2.3 55.8 1.0 SG A:CYS189 2.3 31.2 1.0 FE1 A:SF4802 2.7 55.8 1.0 FE2 A:SF4802 2.7 55.8 1.0 FE4 A:SF4802 2.7 55.8 1.0 CB A:CYS189 3.1 31.2 1.0 S3 A:SF4802 3.9 55.8 1.0 N A:CYS189 3.9 31.2 1.0 CA A:CYS189 4.1 31.2 1.0 CD1 A:LEU238 4.2 28.2 1.0 CG2 A:ILE213 4.3 41.2 1.0 CG1 A:ILE213 4.5 41.2 1.0 SG A:CYS186 4.6 30.2 1.0 SG A:CYS183 4.7 31.3 1.0 N A:THR187 4.8 30.0 1.0 CB A:ILE213 4.8 41.2 1.0 SG A:CYS233 4.8 28.8 1.0 N A:ARG188 4.9 21.0 1.0

Iron binding site 8 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:55.8 occ:1.00 FE4 A:SF4802 0.0 55.8 1.0 S3 A:SF4802 2.3 55.8 1.0 S1 A:SF4802 2.3 55.8 1.0 S2 A:SF4802 2.3 55.8 1.0 SG A:CYS186 2.3 30.2 1.0 FE2 A:SF4802 2.7 55.8 1.0 FE1 A:SF4802 2.7 55.8 1.0 FE3 A:SF4802 2.7 55.8 1.0 N A:CYS186 3.1 30.2 1.0 CB A:CYS186 3.4 30.2 1.0 N A:THR187 3.6 30.0 1.0 CA A:CYS186 3.7 30.2 1.0 S4 A:SF4802 3.9 55.8 1.0 C A:CYS186 4.0 30.2 1.0 C A:HIS185 4.2 30.3 1.0 N A:ARG188 4.3 21.0 1.0 N A:HIS185 4.3 30.3 1.0 CD A:PRO234 4.4 27.4 1.0 CA A:HIS185 4.5 30.3 1.0 CA A:THR187 4.6 30.0 1.0 SG A:CYS183 4.6 31.3 1.0 SG A:CYS189 4.6 31.2 1.0 N A:CYS189 4.8 31.2 1.0 SG A:CYS233 4.8 28.8 1.0 C A:THR187 4.9 30.0 1.0 CB A:ARG188 4.9 21.0 1.0 CG1 A:ILE184 4.9 28.1 1.0

Iron binding site 9 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:35.4 occ:1.00 FE1 A:FES803 0.0 35.4 1.0 S1 A:FES803 2.2 35.4 1.0 S2 A:FES803 2.2 35.4 1.0 SG A:CYS80 2.3 28.8 1.0 SG A:CYS69 2.3 28.8 1.0 FE2 A:FES803 2.7 35.4 1.0 CB A:CYS80 3.3 28.8 1.0 N A:CYS80 3.4 28.8 1.0 N A:ARG81 3.6 29.1 1.0 CB A:CYS69 3.7 28.8 1.0 CA A:CYS80 3.8 28.8 1.0 C A:CYS80 4.0 28.8 1.0 N A:CYS69 4.1 28.8 1.0 CA A:GLY78 4.1 32.0 1.0 SG A:CYS97 4.1 31.6 1.0 N A:ASN79 4.2 32.2 1.0 C A:GLY78 4.2 32.0 1.0 N A:MET82 4.3 30.1 1.0 N A:TYR70 4.3 25.6 1.0 CA A:CYS69 4.4 28.8 1.0 N A:GLY78 4.5 32.0 1.0 CA A:ARG81 4.5 29.1 1.0 SG A:CYS83 4.6 31.6 1.0 C A:ASN79 4.6 32.2 1.0 C A:CYS69 4.7 28.8 1.0 N A:TYR68 4.8 23.6 1.0 O A:GLY78 4.9 32.0 1.0 C A:ARG81 4.9 29.1 1.0 N A:CYS83 4.9 31.6 1.0

Iron binding site 10 out of 28 in the Cryo-Em Structure of Respiratory Complex I Under Turnover


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Cryo-Em Structure of Respiratory Complex I Under Turnover within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:35.4 occ:1.00 FE2 A:FES803 0.0 35.4 1.0 S2 A:FES803 2.2 35.4 1.0 S1 A:FES803 2.2 35.4 1.0 SG A:CYS83 2.3 31.6 1.0 SG A:CYS97 2.3 31.6 1.0 FE1 A:FES803 2.7 35.4 1.0 CB A:CYS97 3.2 31.6 1.0 CB A:CYS83 3.4 31.6 1.0 N A:CYS97 3.8 31.6 1.0 CA A:CYS97 4.1 31.6 1.0 N A:CYS83 4.3 31.6 1.0 SG A:CYS69 4.3 28.8 1.0 CA A:GLY78 4.4 32.0 1.0 CA A:CYS83 4.4 31.6 1.0 SG A:CYS80 4.4 28.8 1.0 N A:SER96 4.6 29.7 1.0 CB A:ALA95 4.6 31.9 1.0 CB A:TYR70 4.8 25.6 1.0 N A:GLY78 5.0 32.0 1.0 C A:ALA95 5.0 31.9 1.0 C A:SER96 5.0 29.7 1.0

K.Parey, J.Lasham, D.J.Mills, A.Djurabekova, O.Haapanen, E.Galemou Yoga, H.Xie, W.Kuhlbrandt, V.Sharma, J.Vonck, V.Zickermann. High-Resolution Structure and Dynamics of Mitochondrial Complex I - Insights Into the Proton Pumping Mechanism, Sci Adv 2021.
ISSN: ESSN 2375-2548