Iron in PDB 7o72: Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna

All present enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna:
2.7.7.6; 3.6.4.12;

The structure of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Fluorine	(F)	3 atoms
Zinc	(Zn)	17 atoms

The binding sites of Iron atom in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna (pdb code 7o72). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna, PDB code: 7o72:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:134.9 occ:1.00 FE1 0:SF4801 0.0 134.9 1.0 SG 0:CYS115 2.3 126.4 1.0 S2 0:SF4801 2.3 134.9 1.0 S3 0:SF4801 2.3 134.9 1.0 S4 0:SF4801 2.3 134.9 1.0 FE2 0:SF4801 2.7 134.9 1.0 FE3 0:SF4801 2.7 134.9 1.0 FE4 0:SF4801 2.7 134.9 1.0 CB 0:CYS115 3.4 126.4 1.0 CA 0:CYS115 3.7 126.4 1.0 S1 0:SF4801 3.9 134.9 1.0 CB 0:HIS117 4.0 132.7 1.0 N 0:LEU116 4.2 127.6 1.0 N 0:HIS117 4.2 132.7 1.0 C 0:CYS115 4.3 126.4 1.0 CA 0:HIS117 4.8 132.7 1.0 SG 0:CYS133 4.8 132.7 1.0 SG 0:CYS156 4.8 142.8 1.0 SG 0:CYS191 4.9 128.6 1.0 CB 0:CYS133 5.0 132.7 1.0 N 0:CYS115 5.0 126.4 1.0

Iron binding site 2 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:134.9 occ:1.00 FE2 0:SF4801 0.0 134.9 1.0 SG 0:CYS156 2.3 142.8 1.0 S1 0:SF4801 2.3 134.9 1.0 S3 0:SF4801 2.3 134.9 1.0 S4 0:SF4801 2.3 134.9 1.0 FE4 0:SF4801 2.7 134.9 1.0 FE1 0:SF4801 2.7 134.9 1.0 FE3 0:SF4801 2.7 134.9 1.0 CB 0:CYS156 3.6 142.8 1.0 S2 0:SF4801 3.9 134.9 1.0 CD2 0:HIS117 4.5 132.7 1.0 CB 0:HIS117 4.5 132.7 1.0 CB 0:TYR158 4.6 134.2 1.0 SG 0:CYS191 4.8 128.6 1.0 SG 0:CYS115 4.8 126.4 1.0 CD1 0:TYR158 4.8 134.2 1.0 CG 0:HIS117 4.8 132.7 1.0 SG 0:CYS133 4.8 132.7 1.0 CA 0:CYS156 4.9 142.8 1.0 N 0:HIS159 4.9 136.2 1.0 CB 0:CYS191 5.0 128.6 1.0 CE 0:MET136 5.0 137.1 1.0

Iron binding site 3 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:134.9 occ:1.00 FE3 0:SF4801 0.0 134.9 1.0 SG 0:CYS133 2.3 132.7 1.0 S1 0:SF4801 2.3 134.9 1.0 S2 0:SF4801 2.3 134.9 1.0 S4 0:SF4801 2.3 134.9 1.0 FE4 0:SF4801 2.7 134.9 1.0 FE1 0:SF4801 2.7 134.9 1.0 FE2 0:SF4801 2.7 134.9 1.0 CB 0:CYS133 3.1 132.7 1.0 CA 0:CYS133 3.8 132.7 1.0 S3 0:SF4801 3.9 134.9 1.0 CE2 0:PHE194 4.2 124.7 1.0 CG2 0:THR137 4.4 136.2 1.0 NE 0:ARG111 4.5 121.0 1.0 SG 0:CYS191 4.6 128.6 1.0 C 0:CYS133 4.7 132.7 1.0 O 0:CYS133 4.7 132.7 1.0 SG 0:CYS115 4.7 126.4 1.0 SG 0:CYS156 4.8 142.8 1.0 CD2 0:PHE194 4.8 124.7 1.0 CD 0:ARG111 4.9 121.0 1.0 N 0:CYS133 5.0 132.7 1.0

Iron binding site 4 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Closed Promoter Dna within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:134.9 occ:1.00 FE4 0:SF4801 0.0 134.9 1.0 SG 0:CYS191 2.3 128.6 1.0 S2 0:SF4801 2.3 134.9 1.0 S1 0:SF4801 2.3 134.9 1.0 S3 0:SF4801 2.3 134.9 1.0 FE3 0:SF4801 2.7 134.9 1.0 FE2 0:SF4801 2.7 134.9 1.0 FE1 0:SF4801 2.7 134.9 1.0 CB 0:CYS191 3.2 128.6 1.0 S4 0:SF4801 3.9 134.9 1.0 CA 0:CYS191 4.2 128.6 1.0 CD2 0:PHE194 4.3 124.7 1.0 CE2 0:PHE194 4.6 124.7 1.0 SG 0:CYS133 4.6 132.7 1.0 SG 0:CYS156 4.7 142.8 1.0 SG 0:CYS115 4.8 126.4 1.0 CA 0:CYS115 4.8 126.4 1.0 CB 0:TYR193 5.0 122.4 1.0 CB 0:TYR158 5.0 134.2 1.0

S.Schilbach, S.Aibara, C.Dienemann, F.Grabbe, P.Cramer. Structure of Rna Polymerase II Pre-Initiation Complex at 2.9 Angstrom Defines Initial Dna Opening Cell(Cambridge,Mass.) 2021.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2021.05.012