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Iron in PDB 7o75: Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna

Enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna

All present enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna:
3.6.4.12;

Other elements in 7o75:

The structure of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Fluorine (F) 3 atoms
Zinc (Zn) 17 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna (pdb code 7o75). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna, PDB code: 7o75:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 7o75

Go back to Iron Binding Sites List in 7o75
Iron binding site 1 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:45.8
occ:1.00
FE1 0:SF4801 0.0 45.8 1.0
SG 0:CYS115 2.3 54.0 1.0
S4 0:SF4801 2.3 45.8 1.0
S2 0:SF4801 2.3 45.8 1.0
S3 0:SF4801 2.3 45.8 1.0
FE3 0:SF4801 2.7 45.8 1.0
FE2 0:SF4801 2.7 45.8 1.0
FE4 0:SF4801 2.7 45.8 1.0
CB 0:CYS115 3.4 54.0 1.0
CA 0:CYS115 3.7 54.0 1.0
S1 0:SF4801 3.9 45.8 1.0
CB 0:HIS117 4.1 60.5 1.0
N 0:LEU116 4.3 58.8 1.0
N 0:HIS117 4.3 60.5 1.0
C 0:CYS115 4.4 54.0 1.0
CG1 0:VAL120 4.7 61.0 1.0
CB 0:CYS133 4.7 60.2 1.0
SG 0:CYS133 4.8 60.2 1.0
SG 0:CYS156 4.8 67.8 1.0
CA 0:HIS117 4.8 60.5 1.0
SG 0:CYS191 4.9 56.8 1.0
N 0:CYS115 4.9 54.0 1.0
CB 0:VAL120 5.0 61.0 1.0

Iron binding site 2 out of 4 in 7o75

Go back to Iron Binding Sites List in 7o75
Iron binding site 2 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:45.8
occ:1.00
FE2 0:SF4801 0.0 45.8 1.0
SG 0:CYS156 2.3 67.8 1.0
S1 0:SF4801 2.3 45.8 1.0
S3 0:SF4801 2.3 45.8 1.0
S4 0:SF4801 2.3 45.8 1.0
FE4 0:SF4801 2.7 45.8 1.0
FE1 0:SF4801 2.7 45.8 1.0
FE3 0:SF4801 2.7 45.8 1.0
CB 0:CYS156 3.5 67.8 1.0
S2 0:SF4801 3.9 45.8 1.0
CB 0:HIS117 4.3 60.5 1.0
CD2 0:HIS117 4.5 60.5 1.0
CB 0:TYR158 4.7 61.2 1.0
SG 0:CYS191 4.7 56.8 1.0
CG 0:HIS117 4.7 60.5 1.0
SG 0:CYS115 4.8 54.0 1.0
SG 0:CYS133 4.8 60.2 1.0
CA 0:CYS156 4.9 67.8 1.0
CD1 0:TYR158 4.9 61.2 1.0
N 0:HIS159 4.9 62.6 1.0

Iron binding site 3 out of 4 in 7o75

Go back to Iron Binding Sites List in 7o75
Iron binding site 3 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:45.8
occ:1.00
FE3 0:SF4801 0.0 45.8 1.0
SG 0:CYS133 2.3 60.2 1.0
S2 0:SF4801 2.3 45.8 1.0
S1 0:SF4801 2.3 45.8 1.0
S4 0:SF4801 2.3 45.8 1.0
FE4 0:SF4801 2.7 45.8 1.0
FE1 0:SF4801 2.7 45.8 1.0
FE2 0:SF4801 2.7 45.8 1.0
CB 0:CYS133 2.9 60.2 1.0
CA 0:CYS133 3.8 60.2 1.0
S3 0:SF4801 3.9 45.8 1.0
CE2 0:PHE194 4.4 51.2 1.0
CG2 0:THR137 4.5 63.8 1.0
C 0:CYS133 4.5 60.2 1.0
O 0:CYS133 4.6 60.2 1.0
SG 0:CYS191 4.6 56.8 1.0
NE 0:ARG111 4.6 51.7 1.0
SG 0:CYS115 4.7 54.0 1.0
SG 0:CYS156 4.8 67.8 1.0
CD2 0:PHE194 4.9 51.2 1.0
N 0:CYS133 4.9 60.2 1.0

Iron binding site 4 out of 4 in 7o75

Go back to Iron Binding Sites List in 7o75
Iron binding site 4 out of 4 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Open Promoter Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:45.8
occ:1.00
FE4 0:SF4801 0.0 45.8 1.0
SG 0:CYS191 2.3 56.8 1.0
S2 0:SF4801 2.3 45.8 1.0
S1 0:SF4801 2.3 45.8 1.0
S3 0:SF4801 2.3 45.8 1.0
FE3 0:SF4801 2.7 45.8 1.0
FE2 0:SF4801 2.7 45.8 1.0
FE1 0:SF4801 2.7 45.8 1.0
CB 0:CYS191 3.3 56.8 1.0
S4 0:SF4801 3.9 45.8 1.0
CA 0:CYS191 4.3 56.8 1.0
CD2 0:PHE194 4.5 51.2 1.0
SG 0:CYS133 4.7 60.2 1.0
SG 0:CYS156 4.7 67.8 1.0
O 0:LEU114 4.7 49.7 1.0
CB 0:TYR193 4.8 51.4 1.0
CE2 0:PHE194 4.8 51.2 1.0
SG 0:CYS115 4.8 54.0 1.0
CA 0:CYS115 4.9 54.0 1.0

Reference:

S.Schilbach, S.Aibara, C.Dienemann, F.Grabbe, P.Cramer. Structure of Rna Polymerase II Pre-Initiation Complex at 2.9 Angstrom Defines Initial Dna Opening Cell(Cambridge,Mass.) 2021.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2021.05.012
Page generated: Thu Aug 8 14:14:07 2024

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