Iron in PDB 7p8n: Tmhydabc- T. Maritima Hydrogenase with Bridge Closed

All present enzymatic activity of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed:
1.12.1.4;

The structure of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 62;

Binding sites:

The binding sites of Iron atom in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed (pdb code 7p8n). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 62 binding sites of Iron where determined in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed, PDB code: 7p8n:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe701 b:52.6 occ:1.00 FE1 a:FES701 0.0 52.6 1.0 S1 a:FES701 2.2 52.6 1.0 S2 a:FES701 2.2 52.6 1.0 SG a:CYS616 2.3 37.7 1.0 SG a:CYS612 2.3 26.0 1.0 FE2 a:FES701 2.7 52.6 1.0 CB a:CYS612 3.0 26.0 1.0 CA a:CYS612 3.5 26.0 1.0 CB a:CYS616 3.9 37.7 1.0 N a:VAL613 4.0 30.9 1.0 N a:CYS616 4.1 37.7 1.0 C a:CYS612 4.2 26.0 1.0 N a:GLU614 4.3 36.8 1.0 CA a:CYS616 4.3 37.7 1.0 SG a:CYS575 4.3 27.9 1.0 N a:ASN615 4.5 35.9 1.0 CB a:SER579 4.7 30.1 1.0 SG a:CYS580 4.7 29.3 1.0 CA a:GLU614 4.8 36.8 1.0 N a:CYS612 4.8 26.0 1.0 C a:ASN615 5.0 35.9 1.0

Iron binding site 2 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe701 b:52.6 occ:1.00 FE2 a:FES701 0.0 52.6 1.0 S2 a:FES701 2.2 52.6 1.0 S1 a:FES701 2.2 52.6 1.0 SG a:CYS580 2.3 29.3 1.0 SG a:CYS575 2.3 27.9 1.0 FE1 a:FES701 2.7 52.6 1.0 CB a:CYS580 3.1 29.3 1.0 CB a:CYS575 3.5 27.9 1.0 N a:CYS580 4.0 29.3 1.0 CA a:CYS612 4.1 26.0 1.0 CA a:CYS580 4.1 29.3 1.0 ND2 a:ASN621 4.3 31.8 1.0 SG a:CYS616 4.4 37.7 1.0 N a:VAL613 4.4 30.9 1.0 CB a:CYS612 4.4 26.0 1.0 SG a:CYS612 4.6 26.0 1.0 N a:GLY577 4.6 26.6 1.0 CA a:GLY577 4.7 26.6 1.0 C a:CYS612 4.8 26.0 1.0 CA a:CYS575 4.8 27.9 1.0 CG2 a:VAL613 5.0 30.9 1.0

Iron binding site 3 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe702 b:15.9 occ:1.00 FE1 a:SF4702 0.0 15.9 1.0 SG a:CYS295 2.3 15.9 1.0 S4 a:SF4702 2.3 15.9 1.0 S3 a:SF4702 2.3 15.9 1.0 S2 a:SF4702 2.3 15.9 1.0 FE2 a:SF4702 2.7 15.9 1.0 FE3 a:SF4702 2.7 15.9 1.0 FE4 a:SF4702 2.7 15.9 1.0 CB a:CYS295 3.4 15.9 1.0 S1 a:SF4702 3.9 15.9 1.0 CA a:CYS295 3.9 15.9 1.0 N a:ALA481 4.0 9.1 1.0 CB a:ALA481 4.2 9.1 1.0 CE a:MET480 4.3 10.3 1.0 CB a:ALA297 4.6 8.1 1.0 CD a:PRO296 4.6 8.4 1.0 C a:CYS295 4.6 15.9 1.0 CA a:ALA481 4.6 9.1 1.0 SG a:CYS350 4.7 7.3 1.0 SG a:CYS482 4.7 11.0 1.0 N a:CYS482 4.7 11.0 1.0 SG a:CYS486 4.7 15.9 1.0 N a:PRO296 4.8 8.4 1.0 N a:ALA297 4.8 8.1 1.0 C a:MET480 4.9 10.3 1.0 CA a:MET480 4.9 10.3 1.0

Iron binding site 4 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe702 b:15.9 occ:1.00 FE2 a:SF4702 0.0 15.9 1.0 SG a:CYS350 2.3 7.3 1.0 S4 a:SF4702 2.3 15.9 1.0 S3 a:SF4702 2.3 15.9 1.0 S1 a:SF4702 2.3 15.9 1.0 FE3 a:SF4702 2.7 15.9 1.0 FE4 a:SF4702 2.7 15.9 1.0 FE1 a:SF4702 2.7 15.9 1.0 CB a:CYS350 2.8 7.3 1.0 S2 a:SF4702 3.9 15.9 1.0 O a:HOH802 4.0 6.3 1.0 CA a:CYS350 4.0 7.3 1.0 O a:HOH941 4.6 15.5 1.0 SG a:CYS486 4.6 15.9 1.0 SG a:CYS482 4.7 11.0 1.0 SG a:CYS295 4.8 15.9 1.0 CB a:ALA352 4.8 6.7 1.0 CD a:PRO296 4.8 8.4 1.0 CG a:LYS353 4.9 7.1 1.0 C a:CYS350 4.9 7.3 1.0 N a:CYS350 5.0 7.3 1.0

Iron binding site 5 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe702 b:15.9 occ:1.00 FE3 a:SF4702 0.0 15.9 1.0 SG a:CYS482 2.3 11.0 1.0 S1 a:SF4702 2.3 15.9 1.0 S4 a:SF4702 2.3 15.9 1.0 S2 a:SF4702 2.3 15.9 1.0 FE2 a:SF4702 2.7 15.9 1.0 FE1 a:SF4702 2.7 15.9 1.0 FE4 a:SF4702 2.7 15.9 1.0 CB a:CYS482 3.2 11.0 1.0 N a:CYS482 3.7 11.0 1.0 S3 a:SF4702 3.9 15.9 1.0 O a:HOH802 4.0 6.3 1.0 CA a:CYS482 4.1 11.0 1.0 CA a:GLY489 4.3 8.6 1.0 O a:GLY485 4.4 9.9 1.0 SG a:CYS350 4.6 7.3 1.0 CB a:ALA481 4.6 9.1 1.0 C a:ALA481 4.6 9.1 1.0 SG a:CYS295 4.7 15.9 1.0 N a:ALA481 4.7 9.1 1.0 CA a:CYS486 4.8 15.9 1.0 CA a:ALA481 4.9 9.1 1.0 SG a:CYS486 4.9 15.9 1.0 O a:CYS189 4.9 15.9 1.0 C a:GLY485 5.0 9.9 1.0

Iron binding site 6 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe702 b:15.9 occ:1.00 FE4 a:SF4702 0.0 15.9 1.0 SG a:CYS486 2.3 15.9 1.0 S1 a:SF4702 2.3 15.9 1.0 S3 a:SF4702 2.3 15.9 1.0 S2 a:SF4702 2.3 15.9 1.0 FE2 a:SF4702 2.7 15.9 1.0 FE1 a:SF4702 2.7 15.9 1.0 FE3 a:SF4702 2.7 15.9 1.0 CB a:CYS486 3.3 15.9 1.0 CA a:CYS486 3.5 15.9 1.0 S4 a:SF4702 3.9 15.9 1.0 N a:CYS486 3.9 15.9 1.0 CE a:MET480 4.0 10.3 1.0 O a:HOH941 4.1 15.5 1.0 C a:GLY485 4.3 9.9 1.0 O a:GLY485 4.4 9.9 1.0 O a:HOH856 4.8 14.4 1.0 CB a:CYS350 4.8 7.3 1.0 C a:CYS486 4.8 15.9 1.0 SG a:CYS295 4.8 15.9 1.0 SG a:CYS482 4.8 11.0 1.0 SG a:CYS350 4.9 7.3 1.0

Iron binding site 7 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe703 b:15.9 occ:1.00 FE1 a:SF4703 0.0 15.9 1.0 SG a:CYS192 2.3 15.9 1.0 S3 a:SF4703 2.3 15.9 1.0 S2 a:SF4703 2.3 15.9 1.0 S4 a:SF4703 2.3 15.9 1.0 FE4 a:SF4703 2.7 15.9 1.0 FE2 a:SF4703 2.7 15.9 1.0 FE3 a:SF4703 2.7 15.9 1.0 CB a:CYS192 3.1 15.9 1.0 N a:CYS192 3.8 15.9 1.0 S1 a:SF4703 3.9 15.9 1.0 CA a:CYS192 4.1 15.9 1.0 O a:HOH942 4.1 14.4 1.0 CD1 a:ILE162 4.7 11.0 1.0 SG a:CYS189 4.7 15.9 1.0 N a:GLN191 4.7 15.9 1.0 SG a:CYS153 4.7 15.9 1.0 N a:GLY190 4.7 10.2 1.0 SG a:CYS186 4.7 15.9 1.0 CA a:GLY190 4.9 10.2 1.0 C a:GLY190 5.0 10.2 1.0

Iron binding site 8 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe703 b:15.9 occ:1.00 FE2 a:SF4703 0.0 15.9 1.0 SG a:CYS189 2.3 15.9 1.0 S4 a:SF4703 2.3 15.9 1.0 S3 a:SF4703 2.3 15.9 1.0 S1 a:SF4703 2.3 15.9 1.0 FE1 a:SF4703 2.7 15.9 1.0 FE3 a:SF4703 2.7 15.9 1.0 FE4 a:SF4703 2.7 15.9 1.0 N a:CYS189 3.6 15.9 1.0 CB a:CYS189 3.7 15.9 1.0 N a:GLY190 3.8 10.2 1.0 S2 a:SF4703 3.9 15.9 1.0 CA a:CYS189 4.1 15.9 1.0 N a:GLN191 4.3 15.9 1.0 CG2 a:VAL187 4.4 11.8 1.0 C a:CYS189 4.4 15.9 1.0 N a:LEU188 4.4 11.3 1.0 C a:LEU188 4.5 11.3 1.0 CG a:GLN157 4.6 14.3 1.0 SG a:CYS192 4.7 15.9 1.0 SG a:CYS186 4.7 15.9 1.0 CA a:LEU188 4.7 11.3 1.0 N a:CYS192 4.8 15.9 1.0 CA a:GLY190 4.8 10.2 1.0 SG a:CYS153 4.8 15.9 1.0 NE2 a:GLN157 4.9 14.3 1.0 CB a:GLN191 4.9 15.9 1.0 C a:GLY190 5.0 10.2 1.0

Iron binding site 9 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe703 b:15.9 occ:1.00 FE3 a:SF4703 0.0 15.9 1.0 SG a:CYS153 2.3 15.9 1.0 S4 a:SF4703 2.3 15.9 1.0 S1 a:SF4703 2.3 15.9 1.0 S2 a:SF4703 2.3 15.9 1.0 FE2 a:SF4703 2.7 15.9 1.0 FE4 a:SF4703 2.7 15.9 1.0 FE1 a:SF4703 2.7 15.9 1.0 CB a:CYS153 3.4 15.9 1.0 S3 a:SF4703 3.9 15.9 1.0 CG1 a:VAL161 3.9 9.9 1.0 CA a:CYS153 4.1 15.9 1.0 CD1 a:ILE162 4.7 11.0 1.0 SG a:CYS189 4.8 15.9 1.0 CG1 a:ILE162 4.8 11.0 1.0 CB a:VAL159 4.8 8.8 1.0 SG a:CYS192 4.8 15.9 1.0 SG a:CYS186 4.8 15.9 1.0 CB a:CYS192 5.0 15.9 1.0

Iron binding site 10 out of 62 in the Tmhydabc- T. Maritima Hydrogenase with Bridge Closed


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Tmhydabc- T. Maritima Hydrogenase with Bridge Closed within 5.0Å range: probe atom residue distance (Å) B Occ a:Fe703 b:15.9 occ:1.00 FE4 a:SF4703 0.0 15.9 1.0 SG a:CYS186 2.3 15.9 1.0 S2 a:SF4703 2.3 15.9 1.0 S3 a:SF4703 2.3 15.9 1.0 S1 a:SF4703 2.3 15.9 1.0 FE1 a:SF4703 2.7 15.9 1.0 FE3 a:SF4703 2.7 15.9 1.0 FE2 a:SF4703 2.7 15.9 1.0 CB a:CYS186 3.5 15.9 1.0 N a:LEU188 3.8 11.3 1.0 S4 a:SF4703 3.9 15.9 1.0 CA a:CYS186 4.0 15.9 1.0 N a:VAL187 4.1 11.8 1.0 CA a:LEU188 4.2 11.3 1.0 CG1 a:VAL161 4.3 9.9 1.0 C a:CYS186 4.4 15.9 1.0 N a:CYS189 4.6 15.9 1.0 SG a:CYS192 4.8 15.9 1.0 SG a:CYS153 4.8 15.9 1.0 C a:VAL187 4.8 11.8 1.0 SG a:CYS189 4.9 15.9 1.0 CD2 a:LEU181 4.9 10.5 1.0 CD1 a:LEU181 4.9 10.5 1.0 C a:LEU188 4.9 11.3 1.0

C.Furlan, N.Chongdar, P.Gupta, W.Lubitz, H.Ogata, J.N.Blaza, J.A.Birrell. Structural Insight on the Mechanism of An Electron-Bifurcating [Fefe] Hydrogenase. Elife V. 11 2022.
ISSN: ESSN 2050-084X
PubMed: 36018003
DOI: 10.7554/ELIFE.79361