Iron in PDB 7pch: Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
Iron Binding Sites:
The binding sites of Iron atom in the Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
(pdb code 7pch). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the
Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex, PDB code: 7pch:
Jump to Iron binding site number:
1;
2;
3;
4;
Iron binding site 1 out
of 4 in 7pch
Go back to
Iron Binding Sites List in 7pch
Iron binding site 1 out
of 4 in the Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Fe201
b:97.8
occ:1.00
|
FE
|
A:HEM201
|
0.0
|
97.8
|
1.0
|
ND
|
A:HEM201
|
2.0
|
97.8
|
1.0
|
NA
|
A:HEM201
|
2.0
|
97.8
|
1.0
|
NC
|
A:HEM201
|
2.1
|
97.8
|
1.0
|
NB
|
A:HEM201
|
2.1
|
97.8
|
1.0
|
NE2
|
A:HIS87
|
2.3
|
101.8
|
1.0
|
C4D
|
A:HEM201
|
3.0
|
97.8
|
1.0
|
C1D
|
A:HEM201
|
3.0
|
97.8
|
1.0
|
C4C
|
A:HEM201
|
3.0
|
97.8
|
1.0
|
C1A
|
A:HEM201
|
3.0
|
97.8
|
1.0
|
C1C
|
A:HEM201
|
3.1
|
97.8
|
1.0
|
C4A
|
A:HEM201
|
3.1
|
97.8
|
1.0
|
C4B
|
A:HEM201
|
3.1
|
97.8
|
1.0
|
C1B
|
A:HEM201
|
3.1
|
97.8
|
1.0
|
CE1
|
A:HIS87
|
3.2
|
101.8
|
1.0
|
CHA
|
A:HEM201
|
3.4
|
97.8
|
1.0
|
CHD
|
A:HEM201
|
3.4
|
97.8
|
1.0
|
CD2
|
A:HIS87
|
3.4
|
101.8
|
1.0
|
CHC
|
A:HEM201
|
3.4
|
97.8
|
1.0
|
CHB
|
A:HEM201
|
3.5
|
97.8
|
1.0
|
NE2
|
A:HIS58
|
3.8
|
106.3
|
1.0
|
CE1
|
A:HIS58
|
4.1
|
106.3
|
1.0
|
C3D
|
A:HEM201
|
4.2
|
97.8
|
1.0
|
C2D
|
A:HEM201
|
4.2
|
97.8
|
1.0
|
C2A
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
C3C
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
C2C
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
C3A
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
C3B
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
C2B
|
A:HEM201
|
4.3
|
97.8
|
1.0
|
ND1
|
A:HIS87
|
4.4
|
101.8
|
1.0
|
CG
|
A:HIS87
|
4.5
|
101.8
|
1.0
|
CG2
|
A:VAL62
|
4.6
|
102.4
|
1.0
|
|
Iron binding site 2 out
of 4 in 7pch
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Iron Binding Sites List in 7pch
Iron binding site 2 out
of 4 in the Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Fe201
b:97.8
occ:1.00
|
FE
|
B:HEM201
|
0.0
|
97.8
|
1.0
|
ND
|
B:HEM201
|
2.0
|
97.8
|
1.0
|
NA
|
B:HEM201
|
2.0
|
97.8
|
1.0
|
NC
|
B:HEM201
|
2.1
|
97.8
|
1.0
|
NB
|
B:HEM201
|
2.1
|
97.8
|
1.0
|
NE2
|
B:HIS92
|
2.4
|
98.7
|
1.0
|
C4D
|
B:HEM201
|
3.0
|
97.8
|
1.0
|
C1D
|
B:HEM201
|
3.0
|
97.8
|
1.0
|
C4C
|
B:HEM201
|
3.0
|
97.8
|
1.0
|
C1A
|
B:HEM201
|
3.0
|
97.8
|
1.0
|
C1C
|
B:HEM201
|
3.1
|
97.8
|
1.0
|
C4B
|
B:HEM201
|
3.1
|
97.8
|
1.0
|
C4A
|
B:HEM201
|
3.1
|
97.8
|
1.0
|
C1B
|
B:HEM201
|
3.1
|
97.8
|
1.0
|
CE1
|
B:HIS92
|
3.3
|
98.7
|
1.0
|
CHA
|
B:HEM201
|
3.3
|
97.8
|
1.0
|
CHD
|
B:HEM201
|
3.4
|
97.8
|
1.0
|
CHC
|
B:HEM201
|
3.4
|
97.8
|
1.0
|
CHB
|
B:HEM201
|
3.5
|
97.8
|
1.0
|
CD2
|
B:HIS92
|
3.5
|
98.7
|
1.0
|
C3D
|
B:HEM201
|
4.2
|
97.8
|
1.0
|
C2D
|
B:HEM201
|
4.2
|
97.8
|
1.0
|
C2A
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
C3C
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
C2C
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
C3B
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
C3A
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
C2B
|
B:HEM201
|
4.3
|
97.8
|
1.0
|
ND1
|
B:HIS92
|
4.5
|
98.7
|
1.0
|
NE2
|
B:HIS63
|
4.5
|
106.0
|
1.0
|
CG
|
B:HIS92
|
4.6
|
98.7
|
1.0
|
CG2
|
B:VAL67
|
4.6
|
98.5
|
1.0
|
|
Iron binding site 3 out
of 4 in 7pch
Go back to
Iron Binding Sites List in 7pch
Iron binding site 3 out
of 4 in the Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Fe201
b:97.8
occ:1.00
|
FE
|
C:HEM201
|
0.0
|
97.8
|
1.0
|
ND
|
C:HEM201
|
2.0
|
97.8
|
1.0
|
NA
|
C:HEM201
|
2.0
|
97.8
|
1.0
|
NC
|
C:HEM201
|
2.1
|
97.8
|
1.0
|
NB
|
C:HEM201
|
2.1
|
97.8
|
1.0
|
NE2
|
C:HIS87
|
2.3
|
101.8
|
1.0
|
C4D
|
C:HEM201
|
3.0
|
97.8
|
1.0
|
C1D
|
C:HEM201
|
3.0
|
97.8
|
1.0
|
C4C
|
C:HEM201
|
3.0
|
97.8
|
1.0
|
C1A
|
C:HEM201
|
3.0
|
97.8
|
1.0
|
C1C
|
C:HEM201
|
3.1
|
97.8
|
1.0
|
C4A
|
C:HEM201
|
3.1
|
97.8
|
1.0
|
C4B
|
C:HEM201
|
3.1
|
97.8
|
1.0
|
C1B
|
C:HEM201
|
3.1
|
97.8
|
1.0
|
CE1
|
C:HIS87
|
3.2
|
101.8
|
1.0
|
CHA
|
C:HEM201
|
3.4
|
97.8
|
1.0
|
CHD
|
C:HEM201
|
3.4
|
97.8
|
1.0
|
CD2
|
C:HIS87
|
3.4
|
101.8
|
1.0
|
CHC
|
C:HEM201
|
3.4
|
97.8
|
1.0
|
CHB
|
C:HEM201
|
3.5
|
97.8
|
1.0
|
NE2
|
C:HIS58
|
3.8
|
106.3
|
1.0
|
CE1
|
C:HIS58
|
4.1
|
106.3
|
1.0
|
C3D
|
C:HEM201
|
4.2
|
97.8
|
1.0
|
C2D
|
C:HEM201
|
4.2
|
97.8
|
1.0
|
C2A
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
C3C
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
C2C
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
C3A
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
C3B
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
C2B
|
C:HEM201
|
4.3
|
97.8
|
1.0
|
ND1
|
C:HIS87
|
4.4
|
101.8
|
1.0
|
CG
|
C:HIS87
|
4.5
|
101.8
|
1.0
|
CG2
|
C:VAL62
|
4.6
|
102.4
|
1.0
|
|
Iron binding site 4 out
of 4 in 7pch
Go back to
Iron Binding Sites List in 7pch
Iron binding site 4 out
of 4 in the Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Human Carboxyhemoglobin Bound to Staphylococcus Aureus Hemophore Isdb - 1:2 Complex within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Fe201
b:97.8
occ:1.00
|
FE
|
D:HEM201
|
0.0
|
97.8
|
1.0
|
ND
|
D:HEM201
|
2.0
|
97.8
|
1.0
|
NA
|
D:HEM201
|
2.0
|
97.8
|
1.0
|
NC
|
D:HEM201
|
2.1
|
97.8
|
1.0
|
NB
|
D:HEM201
|
2.1
|
97.8
|
1.0
|
NE2
|
D:HIS92
|
2.4
|
98.7
|
1.0
|
C4D
|
D:HEM201
|
3.0
|
97.8
|
1.0
|
C1D
|
D:HEM201
|
3.0
|
97.8
|
1.0
|
C4C
|
D:HEM201
|
3.0
|
97.8
|
1.0
|
C1A
|
D:HEM201
|
3.0
|
97.8
|
1.0
|
C1C
|
D:HEM201
|
3.1
|
97.8
|
1.0
|
C4B
|
D:HEM201
|
3.1
|
97.8
|
1.0
|
C4A
|
D:HEM201
|
3.1
|
97.8
|
1.0
|
C1B
|
D:HEM201
|
3.1
|
97.8
|
1.0
|
CE1
|
D:HIS92
|
3.3
|
98.7
|
1.0
|
CHA
|
D:HEM201
|
3.3
|
97.8
|
1.0
|
CHD
|
D:HEM201
|
3.4
|
97.8
|
1.0
|
CHC
|
D:HEM201
|
3.4
|
97.8
|
1.0
|
CHB
|
D:HEM201
|
3.5
|
97.8
|
1.0
|
CD2
|
D:HIS92
|
3.5
|
98.7
|
1.0
|
C3D
|
D:HEM201
|
4.2
|
97.8
|
1.0
|
C2D
|
D:HEM201
|
4.2
|
97.8
|
1.0
|
C2A
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
C3C
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
C2C
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
C3B
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
C3A
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
C2B
|
D:HEM201
|
4.3
|
97.8
|
1.0
|
ND1
|
D:HIS92
|
4.5
|
98.7
|
1.0
|
NE2
|
D:HIS63
|
4.5
|
106.0
|
1.0
|
CG
|
D:HIS92
|
4.6
|
98.7
|
1.0
|
CG2
|
D:VAL67
|
4.6
|
98.5
|
1.0
|
|
Reference:
O.De Bei,
M.Marchetti,
L.Ronda,
E.Gianquinto,
L.Lazzarato,
D.Y.Chirgadze,
S.W.Hardwick,
L.R.Cooper,
F.Spyrakis,
B.F.Luisi,
B.Campanini,
S.Bettati.
Cryo-Em Structures of Staphylococcal Isdb Bound to Human Hemoglobin Reveal the Process of Heme Extraction. Proc.Natl.Acad.Sci.Usa V. 119 08119 2022.
ISSN: ESSN 1091-6490
PubMed: 35357971
DOI: 10.1073/PNAS.2116708119
Page generated: Thu Aug 8 16:30:23 2024
|