Iron in PDB 7tl4: Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF

The structure of Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF, PDB code: 7tl4 was solved by A.M.Blee, L.E.Salay, W.J.Chazin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.61 / 1.81
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.519, 51.488, 90.027, 90, 90, 90
R / Rfree (%)	19.6 / 21.4

The binding sites of Iron atom in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF (pdb code 7tl4). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF, PDB code: 7tl4:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:27.4 occ:1.00 FE1 A:SF4601 0.0 27.4 1.0 S4 A:SF4601 2.2 25.8 1.0 S2 A:SF4601 2.3 24.9 1.0 S3 A:SF4601 2.3 27.1 1.0 SG A:CYS336 2.4 25.0 1.0 FE4 A:SF4601 2.7 29.4 1.0 FE3 A:SF4601 2.7 27.6 1.0 FE2 A:SF4601 2.7 27.5 1.0 CB A:CYS336 3.3 24.5 1.0 S1 A:SF4601 3.8 29.1 1.0 N A:CYS336 4.1 24.5 1.0 CG A:PRO500 4.2 29.8 1.0 CB A:PRO334 4.3 28.1 1.0 CA A:CYS336 4.3 24.2 1.0 CG A:PRO334 4.4 27.9 1.0 CB A:PRO500 4.7 29.9 1.0 SG A:CYS417 4.9 29.5 1.0 CD1 A:ILE420 4.9 27.4 1.0 SG A:CYS474 4.9 27.9 1.0 SG A:CYS434 5.0 28.4 1.0

Iron binding site 2 out of 4 in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:27.5 occ:1.00 FE2 A:SF4601 0.0 27.5 1.0 S1 A:SF4601 2.2 29.1 1.0 S3 A:SF4601 2.3 27.1 1.0 S4 A:SF4601 2.3 25.8 1.0 SG A:CYS417 2.4 29.5 1.0 FE3 A:SF4601 2.7 27.6 1.0 FE4 A:SF4601 2.7 29.4 1.0 FE1 A:SF4601 2.7 27.4 1.0 CB A:CYS417 3.4 29.6 1.0 S2 A:SF4601 3.9 24.9 1.0 CA A:CYS417 4.1 29.2 1.0 CG A:PRO500 4.3 29.8 1.0 CD A:PRO500 4.6 30.7 1.0 SG A:CYS474 4.7 27.9 1.0 CM A:MPD602 4.7 35.0 1.0 CG2 A:THR471 4.8 31.9 1.0 N A:PRO500 4.8 29.8 1.0 SG A:CYS336 4.9 25.0 1.0 N A:CYS417 4.9 28.4 1.0

Iron binding site 3 out of 4 in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:27.6 occ:1.00 FE3 A:SF4601 0.0 27.6 1.0 S2 A:SF4601 2.2 24.9 1.0 S4 A:SF4601 2.3 25.8 1.0 S1 A:SF4601 2.3 29.1 1.0 SG A:CYS474 2.4 27.9 1.0 FE1 A:SF4601 2.7 27.4 1.0 FE2 A:SF4601 2.7 27.5 1.0 FE4 A:SF4601 2.7 29.4 1.0 CB A:CYS474 3.2 28.1 1.0 S3 A:SF4601 3.9 27.1 1.0 CE2 A:PHE436 4.1 28.0 1.0 CB A:PRO334 4.2 28.1 1.0 CD2 A:PHE436 4.4 27.3 1.0 O A:HOH735 4.5 29.4 1.0 CM A:MPD602 4.6 35.0 1.0 CA A:CYS474 4.6 28.5 1.0 SG A:CYS417 4.7 29.5 1.0 SG A:CYS336 4.9 25.0 1.0

Iron binding site 4 out of 4 in the Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Crystal Structure of Yeast P58C Multi-Tyrosine Mutant 6YF within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe601 b:29.4 occ:1.00 FE4 A:SF4601 0.0 29.4 1.0 S1 A:SF4601 2.2 29.1 1.0 S3 A:SF4601 2.3 27.1 1.0 S2 A:SF4601 2.3 24.9 1.0 SG A:CYS434 2.5 28.4 1.0 FE1 A:SF4601 2.7 27.4 1.0 FE3 A:SF4601 2.7 27.6 1.0 FE2 A:SF4601 2.7 27.5 1.0 CB A:CYS434 3.4 27.7 1.0 S4 A:SF4601 3.9 25.8 1.0 CA A:CYS434 4.0 27.0 1.0 CD2 A:PHE436 4.1 27.3 1.0 CE2 A:PHE436 4.6 28.0 1.0 C A:CYS434 4.7 26.8 1.0 SG A:CYS336 4.8 25.0 1.0 CD A:PRO435 4.8 26.4 1.0 SG A:CYS474 4.8 27.9 1.0 CB A:CYS336 4.9 24.5 1.0 CB A:CYS474 4.9 28.1 1.0 N A:PRO435 4.9 26.5 1.0 SG A:CYS417 5.0 29.5 1.0

L.E.Salay, A.M.Blee, M.K.Raza, K.S.Gallagher, H.Chen, A.J.Dorfeuille, J.K.Barton, W.J.Chazin. Modification of the 4FE-4S Cluster Charge Transport Pathway Alters Rna Synthesis By Yeast Dna Primase. Biochemistry V. 61 1113 2022.
ISSN: ISSN 0006-2960
PubMed: 35617695
DOI: 10.1021/ACS.BIOCHEM.2C00100