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Atomistry » Iron » PDB 7tqf-7tto » 7tsa » |
Iron in PDB 7tsa: Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-AmineEnzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine
All present enzymatic activity of Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine:
1.14.13.39; Protein crystallography data
The structure of Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine, PDB code: 7tsa
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tsa:
The structure of Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine
(pdb code 7tsa). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine, PDB code: 7tsa: Iron binding site 1 out of 1 in 7tsaGo back to![]() ![]()
Iron binding site 1 out
of 1 in the Structure of Rat Neuronal Nitric Oxide Synthase R349A/H692F Mutant Heme Domain in Complex with 4-Methyl-6-(3-((Methylamino)Methyl) Phenyl)Pyridin-2-Amine
![]() Mono view ![]() Stereo pair view
Reference:
D.Vasu,
H.Li,
C.D.Hardy,
T.L.Poulos,
R.B.Silverman.
2-Aminopyridines with A Shortened Amino Sidechain As Potent, Selective, and Highly Permeable Human Neuronal Nitric Oxide Synthase Inhibitors. Bioorg.Med.Chem. V. 69 16878 2022.
Page generated: Fri Aug 9 02:25:19 2024
ISSN: ESSN 1464-3391 PubMed: 35772285 DOI: 10.1016/J.BMC.2022.116878 |
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