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Iron in PDB 7xbo: Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238
Enzymatic activity of Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238
All present enzymatic activity of Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238:
1.14.15.33;
1.14.15.33;
Protein crystallography data
The structure of Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238, PDB code: 7xbo
was solved by
G.B.Li,
Y.J.Pan,
S.Y.Li,
X.Gao,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 32.70 / 2.20 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 60.119, 108.48, 153.147, 90, 90, 90 |
| R / Rfree (%) | 17.9 / 21.2 |
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238
(pdb code 7xbo). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238, PDB code: 7xbo:
Jump to Iron binding site number: 1; 2;
In total 2 binding sites of Iron where determined in the Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238, PDB code: 7xbo:
Jump to Iron binding site number: 1; 2;
Iron binding site 1 out of 2 in 7xbo
Go back to
Iron Binding Sites List in 7xbo
Iron binding site 1 out
of 2 in the Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238 within 5.0Å range:
|
Iron binding site 2 out of 2 in 7xbo
Go back to
Iron Binding Sites List in 7xbo
Iron binding site 2 out
of 2 in the Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Crystal Structure of 10-Dml-Bound Cytochrome P450 Pikc with the Unnatural Amino Acid P-Acetyl-L-Phenylalanine Incorporated at Position 238 within 5.0Å range:
|
Reference:
Y.J.Pan,
G.B.Li,
X.Gao,
S.Y.Li.
New Mechanistic Insight of Cytochrome P450 Pikc Gained From Site-Specific Mutagenesis By Non-Coding Amino Acids Nat Commun 2023.
ISSN: ESSN 2041-1723
Page generated: Wed Apr 5 07:02:47 2023
ISSN: ESSN 2041-1723
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