Iron in PDB 7xmb: Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Enzymatic activity of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
All present enzymatic activity of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113:
7.1.1.9;
7.1.1.9;
Protein crystallography data
The structure of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb
was solved by
Y.Nishida,
K.Shinzawa-Itoh,
N.Mizuno,
T.Kumasaka,
S.Yoshikawa,
T.Tsukihara,
Y.Shintani,
S.Takashima,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 29.98 / 2.20 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 182.097, 204.337, 177.933, 90, 90, 90 |
| R / Rfree (%) | 17.8 / 20.4 |
Other elements in 7xmb:
The structure of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 also contains other interesting chemical elements:
| Sodium | (Na) | 2 atoms |
| Magnesium | (Mg) | 2 atoms |
| Copper | (Cu) | 6 atoms |
| Zinc | (Zn) | 2 atoms |
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
(pdb code 7xmb). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb:
Jump to Iron binding site number: 1; 2; 3; 4;
In total 4 binding sites of Iron where determined in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113, PDB code: 7xmb:
Jump to Iron binding site number: 1; 2; 3; 4;
Iron binding site 1 out of 4 in 7xmb
Go back to
Iron Binding Sites List in 7xmb
Iron binding site 1 out
of 4 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Iron binding site 2 out of 4 in 7xmb
Go back to
Iron Binding Sites List in 7xmb
Iron binding site 2 out
of 4 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Iron binding site 3 out of 4 in 7xmb
Go back to
Iron Binding Sites List in 7xmb
Iron binding site 3 out
of 4 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Iron binding site 4 out of 4 in 7xmb
Go back to
Iron Binding Sites List in 7xmb
Iron binding site 4 out
of 4 in the Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Crystal Structure of Bovine Heart Cytochrome C Oxidase, the Structure Complexed with An Allosteric Inhibitor T113 within 5.0Å range:
|
Reference:
Y.Nishida,
S.Yanagisawa,
R.Morita,
H.Shigematsu,
K.Shinzawa-Itoh,
H.Yuki,
S.Ogasawara,
K.Shimuta,
T.Iwamoto,
C.Nakabayashi,
W.Matsumura,
H.Kato,
C.Gopalasingam,
T.Nagao,
T.Qaqorh,
Y.Takahashi,
S.Yamazaki,
K.Kamiya,
R.Harada,
N.Mizuno,
H.Takahashi,
Y.Akeda,
M.Ohnishi,
Y.Ishii,
T.Kumasaka,
T.Murata,
K.Muramoto,
T.Tosha,
Y.Shiro,
T.Honma,
Y.Shigeta,
M.Kubo,
S.Takashima,
Y.Shintani.
Identifying Antibiotics Based on Structural Differences in the Conserved Allostery From Mitochondrial Heme-Copper Oxidases. Nat Commun V. 13 7591 2022.
ISSN: ESSN 2041-1723
PubMed: 36481732
DOI: 10.1038/S41467-022-34771-Y
Page generated: Wed Apr 5 07:04:52 2023
ISSN: ESSN 2041-1723
PubMed: 36481732
DOI: 10.1038/S41467-022-34771-Y
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