Iron in PDB 7yvv: ACMP1, R-4-Hydroxymandelate Synthase

All present enzymatic activity of ACMP1, R-4-Hydroxymandelate Synthase:
1.13.11.27;

The structure of ACMP1, R-4-Hydroxymandelate Synthase, PDB code: 7yvv was solved by B.Zhang, H.M.Ge, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	61.60 / 2.10
Space group	P 31
Cell size a, b, c (Å), α, β, γ (°)	71.13, 71.13, 56.281, 90, 90, 120
R / Rfree (%)	14.9 / 19.7

The structure of ACMP1, R-4-Hydroxymandelate Synthase also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Iron atom in the ACMP1, R-4-Hydroxymandelate Synthase (pdb code 7yvv). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the ACMP1, R-4-Hydroxymandelate Synthase, PDB code: 7yvv:

Iron binding site 1 out of 1 in the ACMP1, R-4-Hydroxymandelate Synthase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of ACMP1, R-4-Hydroxymandelate Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe403 b:16.7 occ:1.00 OE1 A:GLU321 1.9 18.5 1.0 O A:HOH666 1.9 4.9 1.0 NE2 A:HIS162 2.2 19.5 1.0 CE1 A:HIS242 2.4 17.3 1.0 CD A:GLU321 3.0 15.7 1.0 CE1 A:HIS162 3.0 17.2 1.0 NE2 A:HIS242 3.3 16.8 1.0 CD2 A:HIS162 3.3 15.8 1.0 OE2 A:GLU321 3.4 14.2 1.0 ND1 A:HIS242 3.4 20.8 1.0 CE1 A:PHE308 4.0 12.8 1.0 NE2 A:GLN306 4.2 20.1 1.0 O A:HOH517 4.2 64.2 1.0 ND1 A:HIS162 4.2 15.3 1.0 CZ A:PHE308 4.2 16.4 1.0 H33 A:IPA401 4.3 30.0 1.0 CG A:GLU321 4.3 14.1 1.0 CG A:HIS162 4.4 17.0 1.0 CD2 A:HIS242 4.5 15.5 1.0 CB A:GLU321 4.6 17.2 1.0 CG A:HIS242 4.6 18.4 1.0 CB A:ALA244 4.6 17.0 1.0 CE2 A:PHE331 4.8 20.4 1.0 H32 A:IPA401 4.9 30.0 1.0 CB A:ALA164 4.9 16.1 1.0

B.Zhang, H.M.Ge. Characterization of ACMP1 As the Native R-4-Hydroxymandelate Synthase From Biosynthetic Pathway of Amycolamycins To Be Published.