Iron in PDB 7z0t: Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)

All present enzymatic activity of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure):
1.17.98.4;

The structure of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) also contains other interesting chemical elements:

Nickel	(Ni)	1 atom
Molybdenum	(Mo)	1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 34;

Binding sites:

The binding sites of Iron atom in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) (pdb code 7z0t). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 34 binding sites of Iron where determined in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure), PDB code: 7z0t:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe602 b:39.2 occ:1.00 FE E:FCO602 0.0 39.2 1.0 C3 E:FCO602 1.8 39.2 1.0 C2 E:FCO602 1.8 39.2 1.0 C1 E:FCO602 1.8 39.2 1.0 SG E:CYS244 2.3 42.4 1.0 NI E:NI601 2.3 60.0 1.0 SG E:CYS534 2.3 36.9 1.0 CB E:CYS244 2.6 42.4 1.0 O3 E:FCO602 2.9 39.2 1.0 N2 E:FCO602 3.0 39.2 1.0 N1 E:FCO602 3.0 39.2 1.0 CB E:CYS534 3.5 36.9 1.0 SG E:CYS241 3.8 47.4 1.0 NE2 E:HIS248 3.9 34.0 1.0 CA E:CYS244 4.1 42.4 1.0 CB E:CYS531 4.2 37.5 1.0 SG E:CYS531 4.4 37.5 1.0 CE1 E:HIS248 4.4 34.0 1.0 CD E:ARG478 4.4 37.1 1.0 CD2 E:HIS248 4.6 34.0 1.0 CB E:ALA476 4.6 36.8 1.0 N E:CYS244 4.7 42.4 1.0 CB E:ALA501 4.8 30.9 1.0 N E:ALA501 4.9 30.9 1.0 CA E:CYS534 4.9 36.9 1.0

Iron binding site 2 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:13.3 occ:1.00 FE1 B:SF4301 0.0 13.3 1.0 S4 B:SF4301 2.3 13.3 1.0 S2 B:SF4301 2.3 13.3 1.0 S3 B:SF4301 2.3 13.3 1.0 SG B:CYS15 2.3 12.6 1.0 FE4 B:SF4301 2.7 13.3 1.0 FE2 B:SF4301 2.7 13.3 1.0 FE3 B:SF4301 2.7 13.3 1.0 N B:CYS15 3.3 12.6 1.0 CB B:CYS15 3.6 12.6 1.0 S1 B:SF4301 3.9 13.3 1.0 CA B:CYS15 3.9 12.6 1.0 N B:HIS16 3.9 15.1 1.0 N B:GLY14 4.2 13.3 1.0 C B:CYS15 4.2 12.6 1.0 N B:THR17 4.3 12.6 1.0 C B:GLY14 4.3 13.3 1.0 CD B:PRO160 4.4 11.3 1.0 SG B:CYS12 4.5 15.0 1.0 SG B:CYS18 4.5 14.1 1.0 CA B:GLY14 4.5 13.3 1.0 CG1 B:ILE13 4.5 13.3 1.0 OG1 B:THR17 4.6 12.6 1.0 N B:ILE13 4.7 13.3 1.0 CB B:THR17 4.8 12.6 1.0 N B:CYS18 4.8 14.1 1.0 CA B:HIS16 4.9 15.1 1.0 SG B:CYS159 4.9 13.3 1.0 C B:ILE13 5.0 13.3 1.0

Iron binding site 3 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:13.3 occ:1.00 FE2 B:SF4301 0.0 13.3 1.0 S4 B:SF4301 2.3 13.3 1.0 S3 B:SF4301 2.3 13.3 1.0 S1 B:SF4301 2.3 13.3 1.0 SG B:CYS159 2.3 13.3 1.0 FE4 B:SF4301 2.7 13.3 1.0 FE3 B:SF4301 2.7 13.3 1.0 FE1 B:SF4301 2.7 13.3 1.0 CB B:CYS159 3.7 13.3 1.0 S2 B:SF4301 3.9 13.3 1.0 CD B:PRO160 4.0 11.3 1.0 CA B:CYS159 4.1 13.3 1.0 CB B:ALA163 4.2 14.2 1.0 OG1 B:THR161 4.4 12.9 1.0 SG B:CYS15 4.4 12.6 1.0 N B:PRO160 4.5 11.3 1.0 CD1 B:LEU164 4.6 16.0 1.0 C B:CYS159 4.6 13.3 1.0 SG B:CYS18 4.8 14.1 1.0 N B:ALA163 4.8 14.2 1.0 N B:THR161 4.9 12.9 1.0 CB B:CYS18 5.0 14.1 1.0

Iron binding site 4 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:13.3 occ:1.00 FE3 B:SF4301 0.0 13.3 1.0 S2 B:SF4301 2.3 13.3 1.0 S1 B:SF4301 2.3 13.3 1.0 S4 B:SF4301 2.3 13.3 1.0 SG B:CYS18 2.3 14.1 1.0 FE2 B:SF4301 2.7 13.3 1.0 FE4 B:SF4301 2.7 13.3 1.0 FE1 B:SF4301 2.7 13.3 1.0 CB B:CYS18 3.3 14.1 1.0 CG B:PRO48 3.7 17.5 1.0 S3 B:SF4301 3.9 13.3 1.0 N B:CYS18 4.0 14.1 1.0 CA B:CYS18 4.3 14.1 1.0 CD1 B:LEU164 4.3 16.0 1.0 CD B:PRO48 4.4 17.5 1.0 SG B:CYS12 4.5 15.0 1.0 CG2 B:VAL39 4.6 18.0 1.0 SG B:CYS159 4.7 13.3 1.0 SG B:CYS15 4.8 12.6 1.0 N B:THR17 4.9 12.6 1.0 CB B:PRO48 4.9 17.5 1.0

Iron binding site 5 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe301 b:13.3 occ:1.00 FE4 B:SF4301 0.0 13.3 1.0 S1 B:SF4301 2.3 13.3 1.0 S2 B:SF4301 2.3 13.3 1.0 S3 B:SF4301 2.3 13.3 1.0 SG B:CYS12 2.3 15.0 1.0 FE2 B:SF4301 2.7 13.3 1.0 FE1 B:SF4301 2.7 13.3 1.0 FE3 B:SF4301 2.7 13.3 1.0 CB B:CYS12 2.9 15.0 1.0 CA B:CYS12 3.3 15.0 1.0 N B:ILE13 3.8 13.3 1.0 S4 B:SF4301 3.9 13.3 1.0 C B:CYS12 3.9 15.0 1.0 N B:GLY14 4.1 13.3 1.0 CD B:PRO48 4.4 17.5 1.0 CB B:ALA163 4.5 14.2 1.0 N B:CYS12 4.5 15.0 1.0 CG B:PRO48 4.6 17.5 1.0 SG B:CYS159 4.7 13.3 1.0 CA B:GLY14 4.7 13.3 1.0 SG B:CYS15 4.9 12.6 1.0 CA B:ILE13 4.9 13.3 1.0 N B:CYS15 4.9 12.6 1.0 SG B:CYS18 4.9 14.1 1.0 C B:ILE13 5.0 13.3 1.0 O B:CYS12 5.0 15.0 1.0

Iron binding site 6 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:17.9 occ:1.00 FE1 B:SF4302 0.0 17.9 1.0 S2 B:SF4302 2.3 17.9 1.0 S3 B:SF4302 2.3 17.9 1.0 S4 B:SF4302 2.3 17.9 1.0 SG B:CYS155 2.3 15.4 1.0 FE3 B:SF4302 2.7 17.9 1.0 FE4 B:SF4302 2.7 17.9 1.0 FE2 B:SF4302 2.7 17.9 1.0 CB B:CYS155 3.0 15.4 1.0 S1 B:SF4302 3.9 17.9 1.0 N B:CYS155 4.0 15.4 1.0 CA B:CYS155 4.1 15.4 1.0 CB B:PRO153 4.3 18.4 1.0 CB B:CYS22 4.7 15.2 1.0 SG B:CYS146 4.7 20.7 1.0 CD1 B:LEU37 4.7 16.7 1.0 SG B:CYS143 4.7 18.1 1.0 CD2 B:LEU50 4.8 19.7 1.0 SG B:CYS22 4.9 15.2 1.0 CD2 B:LEU37 4.9 16.7 1.0

Iron binding site 7 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:17.9 occ:1.00 FE2 B:SF4302 0.0 17.9 1.0 S1 B:SF4302 2.3 17.9 1.0 S4 B:SF4302 2.3 17.9 1.0 S3 B:SF4302 2.3 17.9 1.0 SG B:CYS146 2.3 20.7 1.0 FE1 B:SF4302 2.7 17.9 1.0 FE3 B:SF4302 2.7 17.9 1.0 FE4 B:SF4302 2.7 17.9 1.0 N B:CYS146 3.6 20.7 1.0 CB B:CYS146 3.7 20.7 1.0 S2 B:SF4302 3.9 17.9 1.0 C B:LEU145 3.9 20.4 1.0 CB B:PRO153 4.1 18.4 1.0 CA B:CYS146 4.1 20.7 1.0 CA B:LEU145 4.2 20.4 1.0 CA B:PRO153 4.3 18.4 1.0 N B:LEU145 4.4 20.4 1.0 CE1 B:HIS26 4.4 16.2 1.0 N B:ALA154 4.5 16.4 1.0 OD1 B:ASP144 4.6 19.3 1.0 SG B:CYS155 4.6 15.4 1.0 O B:LEU145 4.6 20.4 1.0 SG B:CYS143 4.6 18.1 1.0 SG B:CYS22 4.7 15.2 1.0 CG B:PRO153 4.9 18.4 1.0 C B:PRO153 5.0 18.4 1.0 NE2 B:HIS26 5.0 16.2 1.0

Iron binding site 8 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:17.9 occ:1.00 FE3 B:SF4302 0.0 17.9 1.0 S1 B:SF4302 2.3 17.9 1.0 S4 B:SF4302 2.3 17.9 1.0 S2 B:SF4302 2.3 17.9 1.0 SG B:CYS22 2.3 15.2 1.0 FE1 B:SF4302 2.7 17.9 1.0 FE4 B:SF4302 2.7 17.9 1.0 FE2 B:SF4302 2.7 17.9 1.0 CB B:CYS22 2.9 15.2 1.0 S3 B:SF4302 3.9 17.9 1.0 CA B:CYS22 3.9 15.2 1.0 CB B:ARG36 4.1 16.9 1.0 CE1 B:HIS26 4.1 16.2 1.0 CD B:ARG36 4.4 16.9 1.0 SG B:CYS146 4.4 20.7 1.0 CD2 B:LEU37 4.5 16.7 1.0 N B:ARG36 4.7 16.9 1.0 C B:CYS22 4.8 15.2 1.0 ND1 B:HIS26 4.8 16.2 1.0 CA B:ARG36 4.8 16.9 1.0 CG B:ARG36 4.9 16.9 1.0 CB B:CYS155 4.9 15.4 1.0 O B:CYS22 4.9 15.2 1.0 SG B:CYS155 4.9 15.4 1.0 SG B:CYS143 4.9 18.1 1.0 N B:CYS22 5.0 15.2 1.0

Iron binding site 9 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe302 b:17.9 occ:1.00 FE4 B:SF4302 0.0 17.9 1.0 S1 B:SF4302 2.3 17.9 1.0 S3 B:SF4302 2.3 17.9 1.0 S2 B:SF4302 2.3 17.9 1.0 SG B:CYS143 2.3 18.1 1.0 FE1 B:SF4302 2.7 17.9 1.0 FE3 B:SF4302 2.7 17.9 1.0 FE2 B:SF4302 2.7 17.9 1.0 CB B:CYS143 3.3 18.1 1.0 CA B:CYS143 3.8 18.1 1.0 S4 B:SF4302 3.9 17.9 1.0 N B:LEU145 4.2 20.4 1.0 C B:CYS143 4.4 18.1 1.0 CA B:LEU145 4.4 20.4 1.0 N B:ASP144 4.5 19.3 1.0 CB B:ARG36 4.5 16.9 1.0 SG B:CYS22 4.8 15.2 1.0 SG B:CYS155 4.8 15.4 1.0 CD2 B:LEU50 4.8 19.7 1.0 CD1 B:LEU50 4.8 19.7 1.0 OD1 B:ASP144 5.0 19.3 1.0 SG B:CYS146 5.0 20.7 1.0

Iron binding site 10 out of 34 in the Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Structure of the Escherichia Coli Formate Hydrogenlyase Complex (Aerobic Preparation, Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe303 b:23.9 occ:1.00 FE1 B:SF4303 0.0 23.9 1.0 S2 B:SF4303 2.3 23.9 1.0 S4 B:SF4303 2.3 23.9 1.0 S3 B:SF4303 2.3 23.9 1.0 SG B:CYS51 2.3 20.9 1.0 FE2 B:SF4303 2.7 23.9 1.0 FE4 B:SF4303 2.7 23.9 1.0 FE3 B:SF4303 2.7 23.9 1.0 CB B:CYS51 3.5 20.9 1.0 N B:HIS53 3.8 23.4 1.0 N B:HIS52 3.8 22.4 1.0 S1 B:SF4303 3.9 23.9 1.0 CA B:CYS51 3.9 20.9 1.0 C B:CYS51 4.2 20.9 1.0 CA B:HIS53 4.3 23.4 1.0 CD B:LYS142 4.4 17.8 1.0 CB B:ALA96 4.5 18.1 1.0 N B:CYS54 4.6 28.6 1.0 C B:HIS52 4.7 22.4 1.0 CA B:HIS52 4.7 22.4 1.0 SG B:CYS54 4.7 28.6 1.0 SG B:CYS92 4.7 21.1 1.0 SG B:CYS59 4.7 24.5 1.0 NZ B:LYS142 4.7 17.8 1.0 CG B:LYS142 5.0 17.8 1.0

R.Steinhilper, G.Hoff, J.Heider, B.J.Murphy. Structure of the Membrane-Bound Formate Hydrogenlyase Complex From Escherichia Coli. Nat Commun V. 13 5395 2022.
ISSN: ESSN 2041-1723
PubMed: 36104349
DOI: 10.1038/S41467-022-32831-X