Iron in PDB 7zm7: Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)

All present enzymatic activity of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm):
3.6.4.12; 7.1.1.2;

The structure of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 28;

Binding sites:

The binding sites of Iron atom in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) (pdb code 7zm7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 28 binding sites of Iron where determined in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm), PDB code: 7zm7:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:15.2 occ:1.00 FE1 A:FES801 0.0 15.2 1.0 SG A:CYS101 2.2 7.5 1.0 SG A:CYS87 2.2 11.6 1.0 S2 A:FES801 2.2 15.2 1.0 S1 A:FES801 2.2 15.2 1.0 CB A:CYS101 2.8 7.5 1.0 FE2 A:FES801 3.0 15.2 1.0 CB A:CYS87 3.4 11.6 1.0 N A:CYS101 3.9 7.5 1.0 CA A:CYS101 3.9 7.5 1.0 SG A:CYS73 4.1 7.5 1.0 O A:ALA81 4.4 7.4 1.0 CA A:CYS87 4.5 11.6 1.0 CB A:ALA99 4.5 6.8 1.0 N A:CYS87 4.6 11.6 1.0 CB A:TYR74 4.6 5.6 1.0 SG A:CYS84 4.8 6.4 1.0 C A:CYS101 4.8 7.5 1.0 CA A:GLY82 4.8 6.5 1.0 N A:ALA102 5.0 7.8 1.0

Iron binding site 2 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe801 b:15.2 occ:1.00 FE2 A:FES801 0.0 15.2 1.0 SG A:CYS84 2.2 6.4 1.0 SG A:CYS73 2.2 7.5 1.0 S1 A:FES801 2.2 15.2 1.0 S2 A:FES801 2.2 15.2 1.0 FE1 A:FES801 3.0 15.2 1.0 CB A:CYS84 3.3 6.4 1.0 CB A:CYS73 3.5 7.5 1.0 N A:CYS73 3.5 7.5 1.0 N A:CYS84 3.8 6.4 1.0 N A:TYR74 3.9 5.6 1.0 CA A:CYS73 3.9 7.5 1.0 CA A:CYS84 3.9 6.4 1.0 N A:ARG85 4.0 7.9 1.0 N A:TYR72 4.2 15.4 1.0 C A:CYS73 4.4 7.5 1.0 C A:CYS84 4.4 6.4 1.0 N A:MET86 4.5 15.4 1.0 O A:ALA81 4.5 7.4 1.0 SG A:CYS87 4.5 11.6 1.0 C A:TYR72 4.6 15.4 1.0 SG A:CYS101 4.7 7.5 1.0 CB A:TYR74 4.8 5.6 1.0 CA A:TYR72 4.9 15.4 1.0 N A:CYS87 4.9 11.6 1.0 CA A:TYR74 4.9 5.6 1.0 CA A:ARG71 4.9 9.7 1.0 CB A:CYS87 5.0 11.6 1.0 C A:ASN83 5.0 6.0 1.0

Iron binding site 3 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:9.8 occ:1.00 FE1 A:SF4802 0.0 9.8 1.0 SG A:CYS137 2.2 15.3 1.0 S2 A:SF4802 2.3 9.8 1.0 S3 A:SF4802 2.3 9.8 1.0 S4 A:SF4802 2.3 9.8 1.0 FE3 A:SF4802 2.7 9.8 1.0 FE2 A:SF4802 2.7 9.8 1.0 FE4 A:SF4802 2.7 9.8 1.0 CB A:CYS137 3.4 15.3 1.0 CA A:CYS137 3.6 15.3 1.0 NE2 A:GLN149 3.7 15.4 1.0 S1 A:SF4802 3.8 9.8 1.0 N A:CYS137 4.2 15.3 1.0 CG A:GLN149 4.3 15.4 1.0 CE C:MET411 4.4 8.6 1.0 CD A:GLN149 4.4 15.4 1.0 NE2 A:HIS133 4.5 6.9 1.0 CB A:CYS140 4.7 15.4 1.0 C A:ASP136 4.7 15.4 1.0 SG A:CYS146 4.8 15.4 1.0 SG A:CYS140 4.8 15.4 1.0 O A:ASP136 4.8 15.4 1.0 C A:CYS137 4.9 15.3 1.0 CD2 A:HIS133 5.0 6.9 1.0

Iron binding site 4 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:9.8 occ:1.00 FE2 A:SF4802 0.0 9.8 1.0 SG A:CYS146 2.2 15.4 1.0 S1 A:SF4802 2.3 9.8 1.0 S3 A:SF4802 2.3 9.8 1.0 S4 A:SF4802 2.3 9.8 1.0 FE1 A:SF4802 2.7 9.8 1.0 FE3 A:SF4802 2.7 9.8 1.0 FE4 A:SF4802 2.8 9.8 1.0 CB A:CYS146 3.0 15.4 1.0 S2 A:SF4802 3.9 9.8 1.0 CG A:GLN149 4.4 15.4 1.0 CG A:GLN142 4.4 7.6 1.0 CB A:GLN142 4.4 7.6 1.0 CA A:CYS146 4.5 15.4 1.0 O A:GLN142 4.6 7.6 1.0 CB A:LEU148 4.6 9.8 1.0 NE2 A:HIS133 4.7 6.9 1.0 SG A:CYS140 4.7 15.4 1.0 N A:GLN149 4.7 15.4 1.0 NE2 A:GLN149 4.7 15.4 1.0 CD A:GLN149 4.7 15.4 1.0 CB A:GLN149 4.8 15.4 1.0 C A:GLN142 4.8 7.6 1.0 SG A:CYS137 4.8 15.3 1.0 CG1 A:VAL239 4.9 5.0 1.0

Iron binding site 5 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:9.8 occ:1.00 FE3 A:SF4802 0.0 9.8 1.0 NE2 A:HIS133 2.2 6.9 1.0 S4 A:SF4802 2.3 9.8 1.0 S2 A:SF4802 2.3 9.8 1.0 S1 A:SF4802 2.3 9.8 1.0 FE1 A:SF4802 2.7 9.8 1.0 FE2 A:SF4802 2.7 9.8 1.0 FE4 A:SF4802 2.7 9.8 1.0 CE1 A:HIS133 3.1 6.9 1.0 CD2 A:HIS133 3.2 6.9 1.0 S3 A:SF4802 3.9 9.8 1.0 ND1 A:HIS133 4.2 6.9 1.0 CG A:HIS133 4.3 6.9 1.0 CD2 A:LEU148 4.4 9.8 1.0 SG A:CYS146 4.5 15.4 1.0 SG A:CYS137 4.5 15.3 1.0 SG A:CYS140 4.6 15.4 1.0 CE C:MET411 4.7 8.6 1.0 CG1 A:VAL239 4.8 5.0 1.0 O A:PRO134 5.0 15.4 1.0 CG A:ARG186 5.0 6.5 1.0 CB A:VAL239 5.0 5.0 1.0

Iron binding site 6 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe802 b:9.8 occ:1.00 FE4 A:SF4802 0.0 9.8 1.0 SG A:CYS140 2.2 15.4 1.0 S3 A:SF4802 2.3 9.8 1.0 S2 A:SF4802 2.3 9.8 1.0 S1 A:SF4802 2.3 9.8 1.0 FE1 A:SF4802 2.7 9.8 1.0 FE3 A:SF4802 2.7 9.8 1.0 FE2 A:SF4802 2.8 9.8 1.0 CB A:CYS140 2.8 15.4 1.0 S4 A:SF4802 3.9 9.8 1.0 CB A:GLN142 4.1 7.6 1.0 O A:ASP136 4.3 15.4 1.0 CA A:CYS140 4.3 15.4 1.0 CA A:CYS137 4.5 15.3 1.0 N A:GLY240 4.6 6.3 1.0 C A:GLN142 4.7 7.6 1.0 SG A:CYS137 4.7 15.3 1.0 CD A:ARG186 4.7 6.5 1.0 N A:GLY143 4.7 6.9 1.0 SG A:CYS146 4.7 15.4 1.0 N A:GLN142 4.8 7.6 1.0 NE2 A:HIS133 4.8 6.9 1.0 CA A:GLN142 4.8 7.6 1.0 C A:ASP136 4.9 15.4 1.0 NE A:ARG186 4.9 6.5 1.0 C A:CYS140 4.9 15.4 1.0 CG A:GLN142 5.0 7.6 1.0

Iron binding site 7 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:14.1 occ:1.00 FE1 A:SF4803 0.0 14.1 1.0 SG A:CYS193 2.2 10.5 1.0 S2 A:SF4803 2.3 14.1 1.0 S3 A:SF4803 2.3 14.1 1.0 S4 A:SF4803 2.3 14.1 1.0 FE4 A:SF4803 2.7 14.1 1.0 FE3 A:SF4803 2.7 14.1 1.0 FE2 A:SF4803 2.7 14.1 1.0 CB A:CYS193 3.6 10.5 1.0 S1 A:SF4803 3.9 14.1 1.0 CG2 A:ILE217 4.1 9.5 1.0 N A:CYS193 4.1 10.5 1.0 CD1 A:LEU242 4.3 6.5 1.0 CA A:CYS193 4.5 10.5 1.0 CG1 A:ILE217 4.5 9.5 1.0 SG A:CYS190 4.6 13.3 1.0 SG A:CYS237 4.6 6.7 1.0 CB A:ILE217 4.6 9.5 1.0 SG A:CYS187 4.7 5.0 1.0 N A:ARG192 4.8 6.0 1.0 N A:THR191 4.9 15.4 1.0 CG A:LEU242 4.9 6.5 1.0

Iron binding site 8 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:14.1 occ:1.00 FE2 A:SF4803 0.0 14.1 1.0 SG A:CYS187 2.2 5.0 1.0 S4 A:SF4803 2.3 14.1 1.0 S1 A:SF4803 2.3 14.1 1.0 S3 A:SF4803 2.3 14.1 1.0 FE3 A:SF4803 2.7 14.1 1.0 FE4 A:SF4803 2.7 14.1 1.0 FE1 A:SF4803 2.7 14.1 1.0 CB A:CYS187 3.4 5.0 1.0 CA A:CYS187 3.8 5.0 1.0 S2 A:SF4803 3.9 14.1 1.0 CG1 A:ILE217 4.1 9.5 1.0 N A:HIS189 4.1 7.2 1.0 N A:ILE188 4.3 15.4 1.0 C A:CYS187 4.5 5.0 1.0 CA A:HIS189 4.5 7.2 1.0 CB A:ILE217 4.6 9.5 1.0 CE A:MET184 4.6 9.0 1.0 N A:CYS190 4.8 13.3 1.0 SG A:CYS237 4.8 6.7 1.0 SG A:CYS190 4.8 13.3 1.0 SG A:CYS193 4.8 10.5 1.0 CG2 A:ILE217 4.9 9.5 1.0 CB A:ALA241 5.0 6.2 1.0

Iron binding site 9 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:14.1 occ:1.00 FE3 A:SF4803 0.0 14.1 1.0 SG A:CYS190 2.2 13.3 1.0 S4 A:SF4803 2.3 14.1 1.0 S1 A:SF4803 2.3 14.1 1.0 S2 A:SF4803 2.3 14.1 1.0 FE2 A:SF4803 2.7 14.1 1.0 FE4 A:SF4803 2.7 14.1 1.0 FE1 A:SF4803 2.7 14.1 1.0 N A:CYS190 3.6 13.3 1.0 CB A:CYS190 3.6 13.3 1.0 N A:THR191 3.7 15.4 1.0 S3 A:SF4803 3.8 14.1 1.0 CA A:CYS190 4.0 13.3 1.0 CD A:PRO238 4.2 6.0 1.0 N A:ARG192 4.2 6.0 1.0 C A:CYS190 4.3 13.3 1.0 SG A:CYS193 4.5 10.5 1.0 C A:HIS189 4.5 7.2 1.0 SG A:CYS237 4.6 6.7 1.0 CG A:PRO238 4.6 6.0 1.0 SG A:CYS187 4.6 5.0 1.0 N A:HIS189 4.6 7.2 1.0 CA A:THR191 4.6 15.4 1.0 CA A:HIS189 4.8 7.2 1.0 CB A:ARG192 4.9 6.0 1.0 C A:THR191 4.9 15.4 1.0 N A:CYS193 4.9 10.5 1.0

Iron binding site 10 out of 28 in the Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Cryoem Structure of Mitochondrial Complex I From Chaetomium Thermophilum (Inhibited By Ddm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe803 b:14.1 occ:1.00 FE4 A:SF4803 0.0 14.1 1.0 SG A:CYS237 2.2 6.7 1.0 S3 A:SF4803 2.3 14.1 1.0 S2 A:SF4803 2.3 14.1 1.0 S1 A:SF4803 2.3 14.1 1.0 FE1 A:SF4803 2.7 14.1 1.0 FE3 A:SF4803 2.7 14.1 1.0 FE2 A:SF4803 2.7 14.1 1.0 CB A:CYS237 3.7 6.7 1.0 S4 A:SF4803 3.8 14.1 1.0 CA A:CYS237 4.2 6.7 1.0 CD1 A:LEU242 4.3 6.5 1.0 CG A:LEU242 4.4 6.5 1.0 CD A:PRO238 4.4 6.0 1.0 CG2 A:VAL239 4.4 5.0 1.0 CB A:ALA241 4.4 6.2 1.0 SG A:CYS190 4.5 13.3 1.0 SG A:CYS193 4.6 10.5 1.0 SG A:CYS187 4.8 5.0 1.0

E.Laube, J.Meier-Credo, J.D.Langer, W.Kuhlbrandt. Conformational Changes in Mitochondrial Complex I of the Thermophilic Eukaryote Chaetomium Thermophilum. Sci Adv V. 8 C9952 2022.
ISSN: ESSN 2375-2548
PubMed: 36427319
DOI: 10.1126/SCIADV.ADC9952