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Atomistry » Iron » PDB 8ca4-8csp » 8cjn » |
Iron in PDB 8cjn: Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070Enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070
All present enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070:
1.14.16.4; Protein crystallography data
The structure of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070, PDB code: 8cjn
was solved by
A.Schuetz,
K.Mallow,
M.Nazare,
E.Specker,
U.Heinemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070
(pdb code 8cjn). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070, PDB code: 8cjn: Iron binding site 1 out of 1 in 8cjnGo back to Iron Binding Sites List in 8cjn
Iron binding site 1 out
of 1 in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor Km-06-070
Mono view Stereo pair view
Reference:
E.Specker,
R.Wesolowski,
A.Schutz,
S.Matthes,
K.Mallow,
M.Wasinska-Kalwa,
L.Winkler,
A.Oder,
N.Alenina,
D.Pleimes,
J.P.Von Kries,
U.Heinemann,
M.Bader,
M.Nazare.
Structure-Based Design of Xanthine-Imidazopyridines and -Imidazothiazoles As Highly Potent and in Vivo Efficacious Tryptophan Hydroxylase Inhibitors. J.Med.Chem. V. 66 14866 2023.
Page generated: Fri Aug 9 21:45:07 2024
ISSN: ISSN 0022-2623 PubMed: 37905925 DOI: 10.1021/ACS.JMEDCHEM.3C01454 |
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