Iron in PDB 8csu: Human Mitochondrial Small Subunit Assembly Intermediate (State C*)

The structure of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) also contains other interesting chemical elements:

Potassium	(K)	5 atoms
Magnesium	(Mg)	26 atoms
Zinc	(Zn)	1 atom

The binding sites of Iron atom in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*) (pdb code 8csu). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 8 binding sites of Iron where determined in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*), PDB code: 8csu:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Iron binding site 1 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ 7:Fe501 b:38.0 occ:1.00 FE1 7:SF4501 0.0 38.0 1.0 S2 7:SF4501 2.2 38.0 1.0 SG 7:CYS404 2.3 48.6 1.0 S4 7:SF4501 2.3 38.0 1.0 S3 7:SF4501 2.3 38.0 1.0 FE3 7:SF4501 2.7 38.0 1.0 FE4 7:SF4501 2.7 38.0 1.0 FE2 7:SF4501 2.7 38.0 1.0 CB 7:CYS404 3.1 48.6 1.0 S1 7:SF4501 3.9 38.0 1.0 NE2 7:HIS335 4.0 45.0 1.0 CD 7:PRO340 4.2 45.9 1.0 CG 7:PRO340 4.5 45.9 1.0 SG 7:CYS333 4.6 41.2 1.0 CA 7:CYS404 4.6 48.6 1.0 SG 7:CYS339 4.6 46.8 1.0 CG2 7:THR389 4.7 42.9 1.0 CD 7:PRO334 4.7 46.3 1.0 CB 7:CYS333 4.7 41.2 1.0 CA 7:CYS333 4.7 41.2 1.0 CD2 7:HIS335 4.8 45.0 1.0 CE1 7:HIS335 4.9 45.0 1.0 SG 7:CYS347 5.0 40.0 1.0

Iron binding site 2 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ 7:Fe501 b:38.0 occ:1.00 FE2 7:SF4501 0.0 38.0 1.0 S1 7:SF4501 2.2 38.0 1.0 SG 7:CYS347 2.3 40.0 1.0 S3 7:SF4501 2.3 38.0 1.0 S4 7:SF4501 2.3 38.0 1.0 FE4 7:SF4501 2.7 38.0 1.0 FE3 7:SF4501 2.7 38.0 1.0 FE1 7:SF4501 2.7 38.0 1.0 CB 7:CYS347 3.2 40.0 1.0 CG2 7:THR389 3.6 42.9 1.0 S2 7:SF4501 3.9 38.0 1.0 CB 7:THR389 4.4 42.9 1.0 CA 7:CYS347 4.6 40.0 1.0 SG 7:CYS404 4.8 48.6 1.0 SG 7:CYS339 4.8 46.8 1.0 CB 7:CYS404 4.8 48.6 1.0 CG 7:PRO332 4.8 38.6 1.0 SG 7:CYS333 4.9 41.2 1.0

Iron binding site 3 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ 7:Fe501 b:38.0 occ:1.00 FE3 7:SF4501 0.0 38.0 1.0 S4 7:SF4501 2.2 38.0 1.0 SG 7:CYS333 2.3 41.2 1.0 S1 7:SF4501 2.3 38.0 1.0 S2 7:SF4501 2.3 38.0 1.0 FE1 7:SF4501 2.7 38.0 1.0 FE4 7:SF4501 2.7 38.0 1.0 FE2 7:SF4501 2.7 38.0 1.0 CB 7:CYS333 3.3 41.2 1.0 CA 7:CYS333 3.6 41.2 1.0 N 7:CYS333 3.9 41.2 1.0 S3 7:SF4501 3.9 38.0 1.0 CG 7:PRO332 4.2 38.6 1.0 CE 7:MET307 4.3 46.5 1.0 C 7:PRO332 4.5 38.6 1.0 SG 7:CYS347 4.6 40.0 1.0 CD 7:PRO332 4.7 38.6 1.0 SG 7:CYS404 4.7 48.6 1.0 SG 7:CYS339 4.8 46.8 1.0 O 7:PRO332 4.9 38.6 1.0 CB 7:PRO332 5.0 38.6 1.0

Iron binding site 4 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ 7:Fe501 b:38.0 occ:1.00 FE4 7:SF4501 0.0 38.0 1.0 S3 7:SF4501 2.3 38.0 1.0 SG 7:CYS339 2.3 46.8 1.0 S1 7:SF4501 2.3 38.0 1.0 S2 7:SF4501 2.3 38.0 1.0 FE1 7:SF4501 2.7 38.0 1.0 FE2 7:SF4501 2.7 38.0 1.0 FE3 7:SF4501 2.7 38.0 1.0 CB 7:CYS339 3.5 46.8 1.0 CE 7:MET307 3.6 46.5 1.0 S4 7:SF4501 3.9 38.0 1.0 CD 7:PRO340 4.1 45.9 1.0 CB 7:CYS347 4.2 40.0 1.0 CA 7:CYS339 4.2 46.8 1.0 NE2 7:HIS303 4.3 43.8 1.0 SG 7:CYS347 4.3 40.0 1.0 SG 7:CYS333 4.5 41.2 1.0 N 7:PRO340 4.7 45.9 1.0 SG 7:CYS404 4.7 48.6 1.0 CG 7:PRO340 4.8 45.9 1.0 C 7:CYS339 4.8 46.8 1.0 CB 7:GLN341 4.9 51.4 1.0 N 7:GLN341 4.9 51.4 1.0

Iron binding site 5 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe201 b:88.4 occ:1.00 FE1 P:FES201 0.0 88.4 1.0 S2 P:FES201 2.2 88.4 1.0 S1 P:FES201 2.2 88.4 1.0 SG P:CYS100 2.3 47.9 1.0 SG P:CYS65 2.3 52.9 1.0 FE2 P:FES201 2.7 88.4 1.0 CB P:CYS100 3.2 47.9 1.0 CB P:CYS65 3.7 52.9 1.0 SG P:CYS68 4.2 54.7 1.0 CB P:CYS68 4.2 54.7 1.0 N P:CYS65 4.3 52.9 1.0 N P:CYS100 4.4 47.9 1.0 CB P:LYS103 4.4 44.7 1.0 CA P:CYS100 4.4 47.9 1.0 CA P:CYS68 4.5 54.7 1.0 CE P:LYS103 4.6 44.7 1.0 SG E:CYS105 4.6 76.6 1.0 CA P:CYS65 4.6 52.9 1.0 N P:CYS68 4.8 54.7 1.0

Iron binding site 6 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe201 b:88.4 occ:1.00 FE2 P:FES201 0.0 88.4 1.0 S1 P:FES201 2.2 88.4 1.0 S2 P:FES201 2.2 88.4 1.0 SG E:CYS105 2.3 76.6 1.0 SG P:CYS68 2.3 54.7 1.0 FE1 P:FES201 2.7 88.4 1.0 CB E:CYS105 3.0 76.6 1.0 CB P:CYS68 3.5 54.7 1.0 CA E:GLY107 4.1 68.8 1.0 N E:GLY107 4.1 68.8 1.0 CA P:CYS68 4.2 54.7 1.0 SG P:CYS65 4.3 52.9 1.0 CA E:CYS105 4.4 76.6 1.0 SG P:CYS100 4.5 47.9 1.0 C E:CYS105 4.6 76.6 1.0 C E:GLY107 4.7 68.8 1.0 O E:CYS105 4.9 76.6 1.0 O E:GLY107 5.0 68.8 1.0

Iron binding site 7 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ T:Fe201 b:65.9 occ:1.00 FE1 T:FES201 0.0 65.9 1.0 S2 T:FES201 2.2 65.9 1.0 S1 T:FES201 2.2 65.9 1.0 SG T:CYS149 2.3 41.5 1.0 SG M:CYS26 2.3 37.0 1.0 FE2 T:FES201 2.7 65.9 1.0 CB T:CYS149 3.6 41.5 1.0 CB M:CYS26 3.8 37.0 1.0 SG T:CYS141 4.0 38.9 1.0 CA T:CYS149 4.3 41.5 1.0 N M:CYS26 4.3 37.0 1.0 C M:GLY25 4.5 31.9 1.0 CD T:PRO150 4.5 39.1 1.0 CA M:CYS26 4.7 37.0 1.0 CA M:GLY25 4.7 31.9 1.0 SG T:CYS139 4.7 39.7 1.0 O M:GLY25 4.9 31.9 1.0

Iron binding site 8 out of 8 in the Human Mitochondrial Small Subunit Assembly Intermediate (State C*)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Human Mitochondrial Small Subunit Assembly Intermediate (State C*) within 5.0Å range: probe atom residue distance (Å) B Occ T:Fe201 b:65.9 occ:1.00 FE2 T:FES201 0.0 65.9 1.0 S2 T:FES201 2.2 65.9 1.0 S1 T:FES201 2.2 65.9 1.0 SG T:CYS141 2.3 38.9 1.0 SG T:CYS139 2.3 39.7 1.0 CB T:CYS139 2.6 39.7 1.0 FE1 T:FES201 2.7 65.9 1.0 CB T:CYS141 3.4 38.9 1.0 CA T:CYS139 4.1 39.7 1.0 SG T:CYS149 4.3 41.5 1.0 N T:CYS141 4.3 38.9 1.0 CA T:CYS141 4.4 38.9 1.0 CB T:CYS149 4.6 41.5 1.0 CA M:GLY25 4.6 31.9 1.0 C T:CYS139 4.6 39.7 1.0 SG M:CYS26 4.7 37.0 1.0 N T:CYS139 4.9 39.7 1.0 N T:ILE140 4.9 33.5 1.0

N.J.Harper, C.Burnside, S.Klinge. Principles of Mitoribosomal Small Subunit Assembly in Eukaryotes. Nature 2022.
ISSN: ESSN 1476-4687
PubMed: 36482135
DOI: 10.1038/S41586-022-05621-0