Iron in PDB 8d4t: Mammalian Civ with Gdn Bound
Enzymatic activity of Mammalian Civ with Gdn Bound
All present enzymatic activity of Mammalian Civ with Gdn Bound:
7.1.1.9;
Other elements in 8d4t:
The structure of Mammalian Civ with Gdn Bound also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Mammalian Civ with Gdn Bound
(pdb code 8d4t). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the
Mammalian Civ with Gdn Bound, PDB code: 8d4t:
Jump to Iron binding site number:
1;
2;
Iron binding site 1 out
of 2 in 8d4t
Go back to
Iron Binding Sites List in 8d4t
Iron binding site 1 out
of 2 in the Mammalian Civ with Gdn Bound
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Mammalian Civ with Gdn Bound within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
N:Fe604
b:19.7
occ:1.00
|
FE
|
N:HEA604
|
0.0
|
19.7
|
1.0
|
NE2
|
N:HIS61
|
2.0
|
16.2
|
1.0
|
NB
|
N:HEA604
|
2.0
|
22.7
|
1.0
|
NC
|
N:HEA604
|
2.0
|
23.2
|
1.0
|
NA
|
N:HEA604
|
2.0
|
22.9
|
1.0
|
ND
|
N:HEA604
|
2.0
|
23.7
|
1.0
|
NE2
|
N:HIS378
|
2.0
|
16.4
|
1.0
|
CE1
|
N:HIS378
|
2.8
|
18.7
|
1.0
|
HE1
|
N:HIS378
|
2.8
|
18.7
|
1.0
|
CE1
|
N:HIS61
|
2.9
|
21.6
|
1.0
|
C1B
|
N:HEA604
|
3.0
|
23.5
|
1.0
|
C4A
|
N:HEA604
|
3.0
|
23.7
|
1.0
|
C4C
|
N:HEA604
|
3.0
|
24.9
|
1.0
|
C4B
|
N:HEA604
|
3.0
|
23.6
|
1.0
|
C1C
|
N:HEA604
|
3.0
|
24.6
|
1.0
|
C4D
|
N:HEA604
|
3.0
|
24.9
|
1.0
|
C1A
|
N:HEA604
|
3.1
|
24.1
|
1.0
|
HE1
|
N:HIS61
|
3.1
|
21.6
|
1.0
|
CD2
|
N:HIS61
|
3.1
|
21.4
|
1.0
|
C1D
|
N:HEA604
|
3.1
|
24.1
|
1.0
|
CD2
|
N:HIS378
|
3.2
|
17.9
|
1.0
|
HD2
|
N:HIS61
|
3.3
|
21.4
|
1.0
|
CHB
|
N:HEA604
|
3.4
|
21.4
|
1.0
|
CHC
|
N:HEA604
|
3.4
|
23.5
|
1.0
|
CHA
|
N:HEA604
|
3.4
|
24.6
|
1.0
|
CHD
|
N:HEA604
|
3.4
|
22.9
|
1.0
|
HD2
|
N:HIS378
|
3.5
|
17.9
|
1.0
|
HE2
|
N:PHE377
|
3.9
|
21.8
|
1.0
|
ND1
|
N:HIS378
|
4.1
|
17.6
|
1.0
|
ND1
|
N:HIS61
|
4.1
|
16.9
|
1.0
|
CG
|
N:HIS61
|
4.1
|
19.0
|
1.0
|
CG
|
N:HIS378
|
4.2
|
15.3
|
1.0
|
C2B
|
N:HEA604
|
4.2
|
24.0
|
1.0
|
C2A
|
N:HEA604
|
4.3
|
21.3
|
1.0
|
C3B
|
N:HEA604
|
4.3
|
24.4
|
1.0
|
C3A
|
N:HEA604
|
4.3
|
23.5
|
1.0
|
C3C
|
N:HEA604
|
4.3
|
24.0
|
1.0
|
C3D
|
N:HEA604
|
4.3
|
22.2
|
1.0
|
C2C
|
N:HEA604
|
4.3
|
25.0
|
1.0
|
C2D
|
N:HEA604
|
4.3
|
23.6
|
1.0
|
HHB
|
N:HEA604
|
4.4
|
21.4
|
1.0
|
HHC
|
N:HEA604
|
4.4
|
23.5
|
1.0
|
HHA
|
N:HEA604
|
4.4
|
24.6
|
1.0
|
HHD
|
N:HEA604
|
4.4
|
22.9
|
1.0
|
HZ
|
N:PHE425
|
4.6
|
23.8
|
1.0
|
HE2
|
N:PHE425
|
4.7
|
20.0
|
1.0
|
HG3
|
N:MET65
|
4.7
|
26.5
|
1.0
|
CE2
|
N:PHE377
|
4.8
|
21.8
|
1.0
|
HD1
|
N:HIS378
|
4.8
|
17.6
|
1.0
|
HB2
|
N:SER34
|
4.8
|
26.2
|
1.0
|
HD1
|
N:HIS61
|
4.9
|
16.9
|
1.0
|
HD12
|
N:ILE37
|
5.0
|
22.5
|
1.0
|
HB3
|
N:SER34
|
5.0
|
26.2
|
1.0
|
|
Iron binding site 2 out
of 2 in 8d4t
Go back to
Iron Binding Sites List in 8d4t
Iron binding site 2 out
of 2 in the Mammalian Civ with Gdn Bound
Mono view
Stereo pair view
|
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Mammalian Civ with Gdn Bound within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
N:Fe605
b:19.3
occ:1.00
|
FE
|
N:HEA605
|
0.0
|
19.3
|
1.0
|
NA
|
N:HEA605
|
2.0
|
19.8
|
1.0
|
NC
|
N:HEA605
|
2.1
|
19.0
|
1.0
|
ND
|
N:HEA605
|
2.1
|
18.1
|
1.0
|
NB
|
N:HEA605
|
2.1
|
18.5
|
1.0
|
NE2
|
N:HIS376
|
2.3
|
20.8
|
1.0
|
C1A
|
N:HEA605
|
3.0
|
18.5
|
1.0
|
C4A
|
N:HEA605
|
3.0
|
18.8
|
1.0
|
C1C
|
N:HEA605
|
3.1
|
19.3
|
1.0
|
C4C
|
N:HEA605
|
3.1
|
20.5
|
1.0
|
C4D
|
N:HEA605
|
3.1
|
18.4
|
1.0
|
C1D
|
N:HEA605
|
3.1
|
21.1
|
1.0
|
C4B
|
N:HEA605
|
3.1
|
22.5
|
1.0
|
C1B
|
N:HEA605
|
3.1
|
20.7
|
1.0
|
CD2
|
N:HIS376
|
3.2
|
20.8
|
1.0
|
CE1
|
N:HIS376
|
3.3
|
22.1
|
1.0
|
HD2
|
N:HIS376
|
3.4
|
20.8
|
1.0
|
HE1
|
N:HIS376
|
3.4
|
22.1
|
1.0
|
CHA
|
N:HEA605
|
3.5
|
17.6
|
1.0
|
CHB
|
N:HEA605
|
3.5
|
19.0
|
1.0
|
CHC
|
N:HEA605
|
3.5
|
20.6
|
1.0
|
CHD
|
N:HEA605
|
3.5
|
21.2
|
1.0
|
C3A
|
N:HEA605
|
4.2
|
17.8
|
1.0
|
HG21
|
N:VAL243
|
4.2
|
18.2
|
1.0
|
C2A
|
N:HEA605
|
4.2
|
18.3
|
1.0
|
HE1
|
N:HIS240
|
4.3
|
21.7
|
1.0
|
HHA
|
N:HEA605
|
4.4
|
17.6
|
1.0
|
C3C
|
N:HEA605
|
4.4
|
21.4
|
1.0
|
CG
|
N:HIS376
|
4.4
|
20.6
|
1.0
|
HHB
|
N:HEA605
|
4.4
|
19.0
|
1.0
|
C2C
|
N:HEA605
|
4.4
|
20.4
|
1.0
|
HHC
|
N:HEA605
|
4.4
|
20.6
|
1.0
|
ND1
|
N:HIS376
|
4.4
|
19.4
|
1.0
|
C3D
|
N:HEA605
|
4.4
|
17.1
|
1.0
|
HHD
|
N:HEA605
|
4.4
|
21.2
|
1.0
|
C2D
|
N:HEA605
|
4.5
|
18.1
|
1.0
|
C2B
|
N:HEA605
|
4.5
|
18.2
|
1.0
|
C3B
|
N:HEA605
|
4.5
|
18.9
|
1.0
|
HG21
|
N:VAL380
|
4.5
|
22.4
|
1.0
|
HA3
|
N:GLY355
|
4.5
|
22.1
|
1.0
|
HE1
|
N:HIS291
|
4.7
|
23.9
|
1.0
|
HA2
|
N:GLY355
|
4.7
|
22.1
|
1.0
|
HB3
|
N:PHE377
|
4.7
|
21.5
|
1.0
|
CU
|
N:CU601
|
4.9
|
21.0
|
1.0
|
HG11
|
N:VAL243
|
4.9
|
17.1
|
1.0
|
|
Reference:
J.M.Di Trani,
A.Moe,
D.Riepl,
P.Saura,
V.R.I.Kaila,
P.Brzezinski,
J.L.Rubinstein.
Structural Basis of Mammalian Complex IV Inhibition By Steroids. Proc.Natl.Acad.Sci.Usa V. 119 28119 2022.
ISSN: ESSN 1091-6490
PubMed: 35858451
DOI: 10.1073/PNAS.2205228119
Page generated: Fri Aug 9 23:15:24 2024
|