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Iron in PDB 8dwe: Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Enzymatic activity of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
All present enzymatic activity of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine:
3.2.2.31;
3.2.2.31;
Protein crystallography data
The structure of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine, PDB code: 8dwe
was solved by
L.P.Russelburg,
M.Demir,
S.S.David,
M.P.Horvath,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 73.12 / 2.20 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 48.63, 137.96, 74.49, 90, 101, 90 |
| R / Rfree (%) | 19.2 / 23.4 |
Other elements in 8dwe:
The structure of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine also contains other interesting chemical elements:
| Calcium | (Ca) | 4 atoms |
Iron Binding Sites:
The binding sites of Iron atom in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
(pdb code 8dwe). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 8 binding sites of Iron where determined in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine, PDB code: 8dwe:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Iron where determined in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine, PDB code: 8dwe:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Iron binding site 1 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 1 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 2 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 2 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 3 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 3 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 4 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 4 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 5 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 5 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 5 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 6 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 6 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 6 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 7 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 7 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 7 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Iron binding site 8 out of 8 in 8dwe
Go back to
Iron Binding Sites List in 8dwe
Iron binding site 8 out
of 8 in the Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 8 of Adenine Glycosylase Muty Variant E43Q in Complex with Dna Containing D(8-Oxo-G) Paired with Substrate Purine within 5.0Å range:
|
Reference:
L.P.Russelburg,
M.Demir,
K.Cedeno,
S.S.David,
M.P.Horvath.
Structural Basis For Base Engagement and Stereochemistry Revealed By Alteration of Catalytic Residue GLU43 in Dna Repair Glycosylase Muty To Be Published.
Page generated: Sat Aug 10 00:27:34 2024
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