Iron in PDB 8e7s: III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6

All present enzymatic activity of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6:
7.1.1.8; 7.1.1.9;

The structure of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 also contains other interesting chemical elements:

Copper

(Cu)

6 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Iron atom in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 (pdb code 8e7s). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 14 binding sites of Iron where determined in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6, PDB code: 8e7s:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe301 b:176.7 occ:1.00 FE1 C:FES301 0.0 176.7 1.0 S2 C:FES301 2.2 176.7 1.0 S1 C:FES301 2.2 176.7 1.0 SG C:CYS178 2.2 163.7 1.0 SG C:CYS159 2.3 167.8 1.0 CB C:CYS178 2.5 163.7 1.0 FE2 C:FES301 2.7 176.7 1.0 CG C:HIS161 2.8 164.1 1.0 CB C:HIS161 2.9 164.1 1.0 OG C:SER183 3.0 167.7 1.0 ND1 C:HIS161 3.1 164.1 1.0 CD2 C:HIS161 3.3 164.1 1.0 CB C:SER183 3.3 167.7 1.0 CE1 C:HIS161 3.7 164.1 1.0 NE2 C:HIS161 3.8 164.1 1.0 N C:SER183 3.9 167.7 1.0 CA C:CYS178 4.0 163.7 1.0 CB C:CYS159 4.0 167.8 1.0 OH C:TYR185 4.0 154.2 1.0 CA C:SER183 4.2 167.7 1.0 CA C:HIS161 4.4 164.1 1.0 N C:HIS181 4.6 144.2 1.0 N C:GLY182 4.7 166.3 1.0 C C:CYS178 4.8 163.7 1.0 N C:CYS178 4.8 163.7 1.0 C C:GLY182 4.8 166.3 1.0 CZ C:TYR185 4.9 154.2 1.0 N C:LEU162 4.9 164.2 1.0 N C:HIS161 4.9 164.1 1.0 C C:HIS181 4.9 144.2 1.0

Iron binding site 2 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe301 b:176.7 occ:1.00 FE2 C:FES301 0.0 176.7 1.0 CE1 C:HIS161 2.0 164.1 1.0 S1 C:FES301 2.2 176.7 1.0 S2 C:FES301 2.2 176.7 1.0 NE2 C:HIS161 2.3 164.1 1.0 N C:HIS181 2.3 144.2 1.0 SG C:CYS178 2.4 163.7 1.0 ND1 C:HIS161 2.5 164.1 1.0 ND1 C:HIS181 2.6 144.2 1.0 FE1 C:FES301 2.7 176.7 1.0 CD2 C:HIS161 2.9 164.1 1.0 CA C:HIS181 3.0 144.2 1.0 CB C:HIS181 3.0 144.2 1.0 CG C:HIS161 3.0 164.1 1.0 CG C:HIS181 3.2 144.2 1.0 C C:CYS180 3.3 164.0 1.0 CB C:CYS180 3.4 164.0 1.0 C C:HIS181 3.4 144.2 1.0 CB C:CYS178 3.7 163.7 1.0 N C:GLY182 3.7 166.3 1.0 CA C:CYS180 3.8 164.0 1.0 CE1 C:HIS181 3.8 144.2 1.0 O C:HIS181 4.0 144.2 1.0 N C:CYS180 4.2 164.0 1.0 CB C:HIS161 4.2 164.1 1.0 O C:CYS180 4.3 164.0 1.0 CD2 C:HIS181 4.5 144.2 1.0 OG C:SER183 4.7 167.7 1.0 NE2 C:HIS181 4.7 144.2 1.0 SG C:CYS159 4.8 167.8 1.0 N C:SER183 4.8 167.7 1.0 SG C:CYS180 4.9 164.0 1.0 O C:CYS178 4.9 163.7 1.0 CA C:GLY182 4.9 166.3 1.0 SG C:CYS164 4.9 164.8 1.0 CA C:CYS178 5.0 163.7 1.0

Iron binding site 3 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ J:Fe404 b:34.1 occ:1.00 FE J:HEM404 0.0 34.1 1.0 ND J:HEM404 1.9 34.1 1.0 NA J:HEM404 1.9 34.1 1.0 NC J:HEM404 2.1 34.1 1.0 NB J:HEM404 2.1 34.1 1.0 NE2 J:HIS82 2.2 37.1 1.0 NE2 J:HIS183 2.5 54.5 1.0 C4D J:HEM404 2.8 34.1 1.0 C1D J:HEM404 2.9 34.1 1.0 CE1 J:HIS82 2.9 37.1 1.0 C1A J:HEM404 2.9 34.1 1.0 C4A J:HEM404 3.0 34.1 1.0 C4C J:HEM404 3.0 34.1 1.0 C1B J:HEM404 3.0 34.1 1.0 C4B J:HEM404 3.1 34.1 1.0 CE1 J:HIS183 3.1 54.5 1.0 C1C J:HEM404 3.1 34.1 1.0 CHA J:HEM404 3.2 34.1 1.0 CHD J:HEM404 3.4 34.1 1.0 CD2 J:HIS82 3.4 37.1 1.0 CHB J:HEM404 3.4 34.1 1.0 CHC J:HEM404 3.5 34.1 1.0 CD2 J:HIS183 3.7 54.5 1.0 C2A J:HEM404 4.1 34.1 1.0 C2D J:HEM404 4.1 34.1 1.0 ND1 J:HIS82 4.1 37.1 1.0 C3D J:HEM404 4.1 34.1 1.0 C3A J:HEM404 4.1 34.1 1.0 C3C J:HEM404 4.2 34.1 1.0 C2B J:HEM404 4.3 34.1 1.0 C2C J:HEM404 4.3 34.1 1.0 C3B J:HEM404 4.3 34.1 1.0 ND1 J:HIS183 4.4 54.5 1.0 CG J:HIS82 4.4 37.1 1.0 CG J:HIS183 4.7 54.5 1.0 CA J:GLY131 5.0 73.7 1.0

Iron binding site 4 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ J:Fe405 b:40.4 occ:1.00 FE J:HEM405 0.0 40.4 1.0 ND J:HEM405 1.9 40.4 1.0 NA J:HEM405 1.9 40.4 1.0 NC J:HEM405 2.1 40.4 1.0 NB J:HEM405 2.1 40.4 1.0 NE2 J:HIS197 2.3 44.9 1.0 NE2 J:HIS96 2.6 51.3 1.0 C4D J:HEM405 2.8 40.4 1.0 C1D J:HEM405 2.9 40.4 1.0 C1A J:HEM405 2.9 40.4 1.0 C4A J:HEM405 3.0 40.4 1.0 C4C J:HEM405 3.0 40.4 1.0 C1B J:HEM405 3.0 40.4 1.0 C4B J:HEM405 3.1 40.4 1.0 C1C J:HEM405 3.1 40.4 1.0 CHA J:HEM405 3.2 40.4 1.0 CD2 J:HIS197 3.3 44.9 1.0 CE1 J:HIS197 3.3 44.9 1.0 CHD J:HEM405 3.4 40.4 1.0 CHB J:HEM405 3.4 40.4 1.0 CD2 J:HIS96 3.5 51.3 1.0 CHC J:HEM405 3.5 40.4 1.0 CE1 J:HIS96 3.6 51.3 1.0 C2A J:HEM405 4.1 40.4 1.0 C2D J:HEM405 4.1 40.4 1.0 C3D J:HEM405 4.1 40.4 1.0 C3A J:HEM405 4.1 40.4 1.0 C3C J:HEM405 4.2 40.4 1.0 C2C J:HEM405 4.3 40.4 1.0 C2B J:HEM405 4.3 40.4 1.0 C3B J:HEM405 4.3 40.4 1.0 ND1 J:HIS197 4.4 44.9 1.0 CG J:HIS197 4.5 44.9 1.0 CG J:HIS96 4.7 51.3 1.0 ND1 J:HIS96 4.7 51.3 1.0

Iron binding site 5 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ K:Fe601 b:196.6 occ:1.00 FE K:HEA601 0.0 196.6 1.0 NA K:HEA601 2.0 196.6 1.0 NC K:HEA601 2.1 196.6 1.0 NB K:HEA601 2.1 196.6 1.0 ND K:HEA601 2.1 196.6 1.0 NE2 K:HIS376 2.4 180.7 1.0 C1A K:HEA601 3.1 196.6 1.0 C4A K:HEA601 3.1 196.6 1.0 C1B K:HEA601 3.1 196.6 1.0 C1C K:HEA601 3.1 196.6 1.0 C1D K:HEA601 3.1 196.6 1.0 C4C K:HEA601 3.1 196.6 1.0 C4D K:HEA601 3.1 196.6 1.0 C4B K:HEA601 3.1 196.6 1.0 CD2 K:HIS376 3.3 180.7 1.0 CE1 K:HIS376 3.4 180.7 1.0 CHA K:HEA601 3.5 196.6 1.0 CHB K:HEA601 3.5 196.6 1.0 CHC K:HEA601 3.5 196.6 1.0 CHD K:HEA601 3.5 196.6 1.0 C3A K:HEA601 4.3 196.6 1.0 C2A K:HEA601 4.3 196.6 1.0 C3C K:HEA601 4.4 196.6 1.0 C2B K:HEA601 4.4 196.6 1.0 C2D K:HEA601 4.4 196.6 1.0 C2C K:HEA601 4.4 196.6 1.0 C3B K:HEA601 4.4 196.6 1.0 C3D K:HEA601 4.4 196.6 1.0 ND1 K:HIS376 4.5 180.7 1.0 CG K:HIS376 4.5 180.7 1.0

Iron binding site 6 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ K:Fe604 b:164.7 occ:1.00 FE K:HEA604 0.0 164.7 1.0 NA K:HEA604 2.0 164.7 1.0 ND K:HEA604 2.1 164.7 1.0 NC K:HEA604 2.1 164.7 1.0 NB K:HEA604 2.1 164.7 1.0 NE2 K:HIS62 2.2 180.0 1.0 NE2 K:HIS378 2.3 173.0 1.0 CE1 K:HIS62 2.7 180.0 1.0 C1A K:HEA604 3.1 164.7 1.0 C4A K:HEA604 3.1 164.7 1.0 CD2 K:HIS378 3.1 173.0 1.0 C1B K:HEA604 3.1 164.7 1.0 C1C K:HEA604 3.1 164.7 1.0 C1D K:HEA604 3.1 164.7 1.0 C4C K:HEA604 3.1 164.7 1.0 C4D K:HEA604 3.1 164.7 1.0 C4B K:HEA604 3.1 164.7 1.0 CD2 K:HIS62 3.4 180.0 1.0 CE1 K:HIS378 3.4 173.0 1.0 CHA K:HEA604 3.5 164.7 1.0 CHB K:HEA604 3.5 164.7 1.0 CHD K:HEA604 3.5 164.7 1.0 CHC K:HEA604 3.5 164.7 1.0 ND1 K:HIS62 3.9 180.0 1.0 CG K:HIS62 4.3 180.0 1.0 C3A K:HEA604 4.3 164.7 1.0 CG K:HIS378 4.3 173.0 1.0 C2A K:HEA604 4.3 164.7 1.0 C3C K:HEA604 4.4 164.7 1.0 C2B K:HEA604 4.4 164.7 1.0 C2D K:HEA604 4.4 164.7 1.0 C2C K:HEA604 4.4 164.7 1.0 C3D K:HEA604 4.4 164.7 1.0 C3B K:HEA604 4.4 164.7 1.0 ND1 K:HIS378 4.4 173.0 1.0

Iron binding site 7 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ L:Fe401 b:42.6 occ:1.00 FE L:HEM401 0.0 42.6 1.0 CE L:MET225 1.7 38.4 1.0 CE1 L:HIS105 1.9 34.5 1.0 ND L:HEM401 1.9 42.6 1.0 NA L:HEM401 2.0 42.6 1.0 NC L:HEM401 2.1 42.6 1.0 NB L:HEM401 2.1 42.6 1.0 NE2 L:HIS105 2.1 34.5 1.0 C4D L:HEM401 2.8 42.6 1.0 C1D L:HEM401 2.9 42.6 1.0 C1A L:HEM401 2.9 42.6 1.0 SD L:MET225 2.9 38.4 1.0 C4A L:HEM401 3.0 42.6 1.0 C4C L:HEM401 3.0 42.6 1.0 C1B L:HEM401 3.0 42.6 1.0 C4B L:HEM401 3.1 42.6 1.0 C1C L:HEM401 3.1 42.6 1.0 ND1 L:HIS105 3.2 34.5 1.0 CHA L:HEM401 3.3 42.6 1.0 CHD L:HEM401 3.4 42.6 1.0 CHB L:HEM401 3.4 42.6 1.0 CD2 L:HIS105 3.5 34.5 1.0 CHC L:HEM401 3.5 42.6 1.0 CG L:HIS105 4.0 34.5 1.0 C2A L:HEM401 4.1 42.6 1.0 C2D L:HEM401 4.1 42.6 1.0 C3D L:HEM401 4.1 42.6 1.0 C3A L:HEM401 4.1 42.6 1.0 CG L:MET225 4.2 38.4 1.0 C3C L:HEM401 4.2 42.6 1.0 C2B L:HEM401 4.3 42.6 1.0 C2C L:HEM401 4.3 42.6 1.0 C3B L:HEM401 4.3 42.6 1.0

Iron binding site 8 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ c:Fe301 b:189.6 occ:1.00 FE1 c:FES301 0.0 189.6 1.0 S2 c:FES301 2.2 189.6 1.0 S1 c:FES301 2.2 189.6 1.0 SG c:CYS178 2.3 163.0 1.0 SG c:CYS159 2.3 165.2 1.0 FE2 c:FES301 2.7 189.6 1.0 CB c:HIS161 3.1 168.8 1.0 ND1 c:HIS181 3.1 171.0 1.0 CG c:HIS161 3.1 168.8 1.0 ND1 c:HIS161 3.2 168.8 1.0 CE1 c:HIS181 3.4 171.0 1.0 CB c:CYS159 3.7 165.2 1.0 SG c:CYS180 3.7 177.0 1.0 CD2 c:HIS161 3.8 168.8 1.0 CB c:CYS178 3.8 163.0 1.0 CE1 c:HIS161 3.9 168.8 1.0 O c:CYS164 4.1 183.8 1.0 CG c:HIS181 4.1 171.0 1.0 NE2 c:HIS161 4.2 168.8 1.0 SG c:CYS164 4.3 183.8 1.0 OH c:TYR185 4.4 143.2 1.0 NE2 c:HIS181 4.4 171.0 1.0 N c:LEU162 4.5 178.8 1.0 CA c:HIS161 4.5 168.8 1.0 CB c:HIS181 4.8 171.0 1.0 CD2 c:HIS181 4.8 171.0 1.0 C c:HIS161 4.9 168.8 1.0 N c:HIS161 4.9 168.8 1.0 CA c:CYS159 5.0 165.2 1.0

Iron binding site 9 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ c:Fe301 b:189.6 occ:1.00 FE2 c:FES301 0.0 189.6 1.0 CE1 c:HIS161 1.6 168.8 1.0 ND1 c:HIS161 1.8 168.8 1.0 CE1 c:HIS181 1.9 171.0 1.0 ND1 c:HIS181 2.1 171.0 1.0 S1 c:FES301 2.2 189.6 1.0 S2 c:FES301 2.2 189.6 1.0 NE2 c:HIS181 2.2 171.0 1.0 NE2 c:HIS161 2.2 168.8 1.0 CG c:HIS181 2.5 171.0 1.0 CG c:HIS161 2.5 168.8 1.0 CD2 c:HIS181 2.5 171.0 1.0 FE1 c:FES301 2.7 189.6 1.0 CD2 c:HIS161 2.7 168.8 1.0 CB c:HIS181 3.6 171.0 1.0 CB c:HIS161 3.7 168.8 1.0 SG c:CYS180 4.5 177.0 1.0 SG c:CYS178 4.5 163.0 1.0 N c:LEU162 4.6 178.8 1.0 CB c:LEU162 4.6 178.8 1.0 CD1 c:LEU162 4.6 178.8 1.0 SG c:CYS164 4.7 183.8 1.0 CA c:HIS181 4.8 171.0 1.0 CA c:HIS161 4.9 168.8 1.0 C c:HIS161 4.9 168.8 1.0 N c:HIS181 4.9 171.0 1.0 SG c:CYS159 4.9 165.2 1.0

Iron binding site 10 out of 14 in the III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of III2IV2 Respiratory Supercomplex From Saccharomyces Cerevisiae with 4 Bound UQ6 within 5.0Å range: probe atom residue distance (Å) B Occ j:Fe403 b:36.9 occ:1.00 FE j:HEM403 0.0 36.9 1.0 ND j:HEM403 1.9 36.9 1.0 NA j:HEM403 2.0 36.9 1.0 NC j:HEM403 2.1 36.9 1.0 NB j:HEM403 2.1 36.9 1.0 CE1 j:HIS82 2.1 32.0 1.0 NE2 j:HIS82 2.2 32.0 1.0 NE2 j:HIS183 2.4 54.5 1.0 C4D j:HEM403 2.8 36.9 1.0 C1D j:HEM403 2.9 36.9 1.0 C1A j:HEM403 2.9 36.9 1.0 C4A j:HEM403 3.0 36.9 1.0 CE1 j:HIS183 3.0 54.5 1.0 C4C j:HEM403 3.0 36.9 1.0 C1B j:HEM403 3.0 36.9 1.0 C4B j:HEM403 3.1 36.9 1.0 C1C j:HEM403 3.1 36.9 1.0 CHA j:HEM403 3.2 36.9 1.0 CHD j:HEM403 3.4 36.9 1.0 ND1 j:HIS82 3.4 32.0 1.0 CHB j:HEM403 3.4 36.9 1.0 CHC j:HEM403 3.5 36.9 1.0 CD2 j:HIS82 3.5 32.0 1.0 CD2 j:HIS183 3.6 54.5 1.0 C2A j:HEM403 4.1 36.9 1.0 C2D j:HEM403 4.1 36.9 1.0 CG j:HIS82 4.1 32.0 1.0 C3D j:HEM403 4.1 36.9 1.0 C3A j:HEM403 4.1 36.9 1.0 C3C j:HEM403 4.2 36.9 1.0 ND1 j:HIS183 4.3 54.5 1.0 C2B j:HEM403 4.3 36.9 1.0 C2C j:HEM403 4.3 36.9 1.0 C3B j:HEM403 4.3 36.9 1.0 CG j:HIS183 4.6 54.5 1.0

C.F.Hryc, V.K.P.S.Mallampalli, E.I.Bovshik, S.Azinas, G.Fan, I.I.Serysheva, G.C.Sparagna, M.L.Baker, E.Mileykovskaya, W.Dowhan. Structural Insights Into Cardiolipin Replacement By Phosphatidylglycerol in A Cardiolipin-Lacking Yeast Respiratory Supercomplex. Nat Commun V. 14 2783 2023.
ISSN: ESSN 2041-1723
PubMed: 37188665
DOI: 10.1038/S41467-023-38441-5