Iron in PDB 8jai: Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1

All present enzymatic activity of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1:
1.16.3.1;

The structure of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1, PDB code: 8jai was solved by X.Chen, G.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	65.59 / 2.56
Space group	I 41 2 2 3
Cell size a, b, c (Å), α, β, γ (°)	301.66, 301.66, 316.99, 90, 90, 90
R / Rfree (%)	33.5 / 36.8

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 18;

Binding sites:

The binding sites of Iron atom in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 (pdb code 8jai). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 18 binding sites of Iron where determined in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1, PDB code: 8jai:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe201 b:30.9 occ:1.00 OE2 A:GLU27 1.6 63.8 1.0 ND1 A:HIS65 1.7 60.3 1.0 CE1 A:HIS65 2.1 61.7 1.0 CD A:GLU27 2.8 56.5 1.0 CG A:HIS65 3.0 58.5 1.0 OE2 A:GLU62 3.0 57.2 1.0 NE2 A:HIS65 3.4 72.5 1.0 OE1 A:GLU27 3.5 58.8 1.0 OE1 A:GLN141 3.7 59.3 1.0 CD2 A:HIS65 3.8 62.1 1.0 CB A:HIS65 3.8 56.5 1.0 CG A:GLU27 3.9 49.7 1.0 CD A:GLU62 4.0 50.9 1.0 OE1 A:GLU62 4.3 62.3 1.0 CG1 A:VAL110 4.6 51.3 1.0 CD1 A:TYR137 4.7 60.8 1.0 CD A:GLN141 4.7 54.2 1.0 CB A:GLU27 4.8 40.5 1.0

Iron binding site 2 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:30.9 occ:1.00 ND1 B:HIS65 1.9 54.1 1.0 CE1 B:HIS65 2.0 55.3 1.0 NE2 B:GLN141 2.4 49.4 1.0 OE2 B:GLU27 2.8 35.5 1.0 CG B:HIS65 3.2 51.1 1.0 OE2 B:GLU62 3.2 44.9 1.0 NE2 B:HIS65 3.2 72.5 1.0 CD B:GLN141 3.4 45.0 1.0 CD B:GLU27 3.6 36.3 1.0 CD2 B:HIS65 3.8 55.1 1.0 OE1 B:GLU27 3.8 42.7 1.0 OE1 B:GLU62 3.8 53.6 1.0 CD B:GLU62 3.9 40.7 1.0 OE1 B:GLN141 4.0 53.2 1.0 CB B:HIS65 4.1 41.6 1.0 CG1 B:VAL110 4.2 38.0 1.0 CG B:GLN141 4.5 45.0 1.0 CD2 B:TYR137 4.7 41.3 1.0 FE B:FE202 4.9 30.9 1.0 CE2 B:TYR137 4.9 43.2 1.0 CG B:GLU27 5.0 34.4 1.0

Iron binding site 3 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe202 b:30.9 occ:1.00 OE1 B:GLU62 1.8 53.6 1.0 OE2 B:GLU107 2.5 46.8 1.0 OE1 B:GLN58 2.6 61.6 1.0 CD B:GLU62 3.0 40.7 1.0 CD B:GLU107 3.5 51.0 1.0 CG B:GLU62 3.8 36.0 1.0 CD B:GLN58 3.8 54.2 1.0 OE2 B:GLU62 3.9 44.9 1.0 OE1 B:GLU107 3.9 53.6 1.0 CE2 B:TYR34 3.9 37.7 1.0 OE2 B:GLU61 4.2 72.5 1.0 OH B:TYR34 4.2 48.3 1.0 O B:GLN58 4.2 36.1 1.0 CZ B:TYR34 4.4 43.8 1.0 NE2 B:GLN58 4.6 57.2 1.0 CB B:GLN58 4.8 44.9 1.0 CD2 B:TYR34 4.8 33.0 1.0 NE2 B:GLN141 4.8 49.4 1.0 CG B:GLN58 4.8 42.0 1.0 CG B:GLU107 4.9 46.4 1.0 FE B:FE201 4.9 30.9 1.0 CB B:GLU61 5.0 53.8 1.0 CA B:GLN58 5.0 37.5 1.0

Iron binding site 4 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe201 b:30.9 occ:1.00 OE1 D:GLU140 1.9 73.7 1.0 CD1 D:TYR137 2.5 68.1 1.0 CD D:GLU140 2.7 79.2 1.0 CE1 D:TYR137 3.0 62.8 1.0 OE2 D:GLU140 3.3 86.4 1.0 CG D:GLU140 3.6 77.4 1.0 CG D:TYR137 3.7 68.5 1.0 O D:TYR137 3.8 63.0 1.0 CG D:GLN141 3.9 67.3 1.0 ND1 D:HIS65 3.9 72.3 1.0 CE1 D:HIS65 4.0 74.2 1.0 CB D:GLU140 4.0 75.0 1.0 CB D:TYR137 4.2 53.6 1.0 OE1 D:GLN141 4.2 56.2 1.0 CD1 D:LEU114 4.2 53.4 1.0 CG D:HIS65 4.3 71.5 1.0 NE2 D:HIS65 4.3 78.4 1.0 CD D:GLN141 4.3 57.2 1.0 CA D:TYR137 4.4 56.6 1.0 CZ D:TYR137 4.4 58.1 1.0 CD2 D:HIS65 4.5 75.3 1.0 C D:TYR137 4.6 62.4 1.0 CG1 D:VAL110 4.6 65.2 1.0 OE1 D:GLU27 4.6 54.2 1.0 OE2 D:GLU27 4.7 53.8 1.0 N D:GLN141 4.8 69.3 1.0 CD2 D:TYR137 4.9 71.7 1.0 CB D:HIS65 4.9 63.8 1.0

Iron binding site 5 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe201 b:30.9 occ:1.00 OE1 E:GLN58 1.8 61.6 1.0 OE2 E:GLU107 2.8 55.6 1.0 OE1 E:GLU62 2.8 63.2 1.0 CD E:GLN58 3.0 49.6 1.0 CE2 E:TYR34 3.2 43.9 1.0 FE E:FE202 3.3 30.9 1.0 CG E:GLU62 3.3 52.8 1.0 CD E:GLU62 3.4 53.2 1.0 CD E:GLU107 3.5 59.1 1.0 CG E:GLN58 3.7 40.4 1.0 CB E:GLN58 3.8 37.5 1.0 OH E:TYR34 3.8 49.4 1.0 CZ E:TYR34 3.8 47.7 1.0 O E:GLN58 4.0 41.4 1.0 CD2 E:TYR34 4.0 35.4 1.0 NE2 E:GLN58 4.1 38.0 1.0 OE1 E:GLU107 4.1 59.1 1.0 CG E:GLU107 4.4 49.5 1.0 CA E:GLN58 4.4 44.6 1.0 OE2 E:GLU62 4.5 56.3 1.0 C E:GLN58 4.6 47.0 1.0 CB E:GLU62 4.8 44.5 1.0 CE1 E:TYR34 5.0 38.0 1.0

Iron binding site 6 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe202 b:30.9 occ:1.00 OE1 E:GLU62 1.8 63.2 1.0 CD E:GLU62 2.5 53.2 1.0 CE1 E:HIS65 2.6 60.4 1.0 OE2 E:GLU62 2.8 56.3 1.0 OE1 E:GLU107 2.9 59.1 1.0 FE E:FE201 3.3 30.9 1.0 ND1 E:HIS65 3.4 42.2 1.0 NE2 E:HIS65 3.4 72.5 1.0 CD E:GLU107 3.5 59.1 1.0 NE2 E:GLN141 3.6 56.0 1.0 OE2 E:GLU107 3.6 55.6 1.0 CG E:GLU62 3.8 52.8 1.0 OE1 E:GLN141 3.9 56.8 1.0 OE1 E:GLN58 4.2 61.6 1.0 CD E:GLN141 4.2 48.6 1.0 CD2 E:HIS65 4.3 50.8 1.0 CG E:HIS65 4.3 53.1 1.0 OE1 E:GLU27 4.6 63.5 1.0 CG E:GLU107 4.8 49.5 1.0 OE2 E:GLU27 4.9 52.4 1.0

Iron binding site 7 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe201 b:30.9 occ:1.00 OE2 F:GLU27 2.5 58.2 1.0 ND1 F:HIS65 2.5 69.1 1.0 OE2 F:GLU62 3.0 63.1 1.0 CD F:GLU27 3.3 57.2 1.0 CE1 F:HIS65 3.3 73.1 1.0 CD F:GLU62 3.4 62.1 1.0 CG F:HIS65 3.4 63.5 1.0 OE1 F:GLU27 3.4 56.3 1.0 OE1 F:GLU62 3.4 66.4 1.0 CB F:HIS65 3.7 59.1 1.0 NE2 F:HIS65 4.4 72.5 1.0 NE2 F:GLN141 4.4 62.5 1.0 CD2 F:HIS65 4.4 69.6 1.0 CE1 F:TYR137 4.4 63.5 1.0 CG F:GLU62 4.5 56.4 1.0 CA F:GLU62 4.6 66.1 1.0 OE2 F:GLU107 4.6 65.0 1.0 CZ F:TYR137 4.6 63.1 1.0 OH F:TYR137 4.6 69.6 1.0 CG F:GLU27 4.7 54.2 1.0 OE1 F:GLU107 4.7 55.3 1.0

Iron binding site 8 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ G:Fe201 b:30.9 occ:1.00 ND1 G:HIS65 1.8 76.1 1.0 OE2 G:GLU62 2.1 65.8 1.0 CE1 G:HIS65 2.1 71.9 1.0 CG G:HIS65 3.2 67.1 1.0 OE1 G:GLN141 3.2 57.5 1.0 CD G:GLU62 3.2 58.1 1.0 NE2 G:HIS65 3.4 72.5 1.0 OE1 G:GLU62 3.6 63.0 1.0 CD2 G:HIS65 3.9 67.3 1.0 OE1 G:GLU27 4.0 63.5 1.0 CB G:HIS65 4.0 65.3 1.0 CD G:GLN141 4.3 55.2 1.0 CG G:GLU62 4.5 59.7 1.0 O G:GLU61 4.5 70.3 1.0 OE2 G:GLU27 4.6 68.8 1.0 CD2 G:TYR137 4.7 56.0 1.0 CD G:GLU27 4.8 65.8 1.0 CG G:GLU140 5.0 78.0 1.0

Iron binding site 9 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ H:Fe201 b:30.9 occ:1.00 OE1 H:GLN141 1.9 65.8 1.0 OE2 H:GLU62 2.1 51.1 1.0 CD H:GLN141 2.8 65.5 1.0 CD H:GLU62 3.0 56.2 1.0 OE1 H:GLU27 3.0 46.1 1.0 OE2 H:GLU27 3.1 53.1 1.0 NE2 H:GLN141 3.2 63.3 1.0 OE1 H:GLU62 3.2 51.1 1.0 CD H:GLU27 3.4 42.1 1.0 CD2 H:HIS65 3.5 57.0 1.0 CG H:HIS65 3.8 57.6 1.0 NE2 H:HIS65 3.8 72.5 1.0 CG H:GLN141 4.0 62.5 1.0 OE2 H:GLU107 4.1 54.1 1.0 ND1 H:HIS65 4.2 68.4 1.0 CE1 H:HIS65 4.2 65.6 1.0 CB H:HIS65 4.3 47.5 1.0 CG H:GLU62 4.4 46.0 1.0 CG1 H:VAL110 4.5 58.3 1.0 CB H:GLU62 4.8 50.4 1.0 OE1 H:GLU107 4.8 61.5 1.0 CD2 H:TYR137 4.9 44.6 1.0 CG H:GLU27 4.9 42.4 1.0 CD H:GLU107 4.9 59.1 1.0 CE2 H:TYR137 5.0 51.8 1.0

Iron binding site 10 out of 18 in the Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Crystal Structure of Human H-Ferritin Variant 123F Assembling in Solution 1 within 5.0Å range: probe atom residue distance (Å) B Occ I:Fe201 b:30.9 occ:1.00 OE2 I:GLU27 1.8 59.5 1.0 OE1 I:GLU27 2.0 60.2 1.0 CD I:GLU27 2.1 52.9 1.0 NE2 I:GLN141 2.6 59.4 1.0 ND1 I:HIS65 3.4 63.9 1.0 CG1 I:VAL110 3.5 44.0 1.0 CG I:GLU27 3.5 53.5 1.0 CD1 I:TYR137 3.7 59.6 1.0 OE2 I:GLU62 3.7 54.1 1.0 CD I:GLN141 3.8 61.0 1.0 CE1 I:TYR137 3.9 69.0 1.0 OE1 I:GLU62 4.0 56.1 1.0 CE1 I:HIS65 4.2 65.8 1.0 CD I:GLU62 4.2 59.9 1.0 CG I:HIS65 4.4 56.9 1.0 CB I:GLU27 4.4 55.9 1.0 OE1 I:GLN141 4.5 53.2 1.0 CB I:HIS65 4.5 52.2 1.0 CD1 I:LEU114 4.6 47.8 1.0 CG I:TYR137 4.8 62.5 1.0 CB I:VAL110 4.8 55.8 1.0 CG I:GLN141 4.9 63.5 1.0 CD2 I:LEU114 5.0 58.2 1.0

X.Chen, T.Zhang, H.Liu, J.Zang, C.Lv, M.Du, G.Zhao. Shape-Anisotropic Assembly of Protein Nanocages with Identical Building Blocks By Designed Intermolecular Pi-Pi Interactions. Adv Sci V. 10 05398 2023.
ISSN: ESSN 2198-3844
PubMed: 37870198
DOI: 10.1002/ADVS.202305398